CAS 101-31-5

(-)-Atropina

Descrição:

(-)-Atropina é um alcaloide tropano derivado de plantas da família Solanaceae, particularmente da beladona (Atropa belladonna) e outras espécies relacionadas. É caracterizado por sua natureza quiral, existindo como um único enantiômero, que é a forma (-), conhecida por sua atividade farmacológica. A atropina é uma amina terciária com uma fórmula molecular de C17H23NO3 e um peso molecular de aproximadamente 289,37 g/mol. É um sólido cristalino incolor a amarelo pálido que é solúvel em solventes orgânicos como álcool e clorofórmio, mas tem solubilidade limitada em água. A atropina atua principalmente como um agente anticolinérgico, bloqueando a ação da acetilcolina nos receptores muscarínicos, o que leva a efeitos como aumento da frequência cardíaca, dilatação das pupilas e redução das secreções. É usada clinicamente para tratar bradicardia, como antídoto para envenenamento por organofosforados e para induzir midríase durante exames oftalmológicos. Devido aos seus efeitos potentes, a atropina deve ser usada com cautela, pois pode causar efeitos colaterais como boca seca, visão turva e taquicardia.

Fórmula: C₁₇H₂₃NO₃

InChI: InChI=1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16-/m1/s1

Chave InChI: InChIKey=RKUNBYITZUJHSG-FXUDXRNXSA-N

SMILES: O(C([C@H](CO)C1=CC=CC=C1)=O)[C@@H]2C[C@]3(N(C)[C@@](C2)(CC3)[H])[H]

Sinónimos:

• (-)-Atropine
• (1R,5S)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl (2S)-3-hydroxy-2-phenylpropanoate
• (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl (2S)-3-hydroxy-2-phenylpropanoate
• (S)-(-)-Hyoscyamine
• (S)-Atropine
• 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropan-3α-ol, (-)-tropate (ester)
• 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropan-3α-yl (-)-tropate
• 1αH,5αH-Tropan-3α-ol, (-)-tropate (ester)
• 1αH,5αH-Tropan-3α-yl (-)-tropate
• 8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl 3-Hydroxy-2-Phenylpropanoate
• 8-methyl-8-azabicyclo[3.2.1]oct-3-yl (2S)-3-hydroxy-2-phenylpropanoate
• <span class="text-smallcaps">L</span>-Hyoscyamin
• <span class="text-smallcaps">L</span>-Hyoscyamine
• Benzeneacetic acid, α-(hydroxymethyl)-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, (αS)-
• Benzeneacetic acid, α-(hydroxymethyl)-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, [3(S)-endo]-
• Cystospaz
• Daturine
• Duboisine
• Hiosciamina
• Hyoscyamin
• L-Hyoscyamin
• L-Hyoscyamine
• L-Hyoscyamine free base
• Tropic acid, 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-tropan-3α-yl ester, (-)-
• l-Atropine
• l-Tropine tropate

L-Hyoscyamine

CAS: 101-31-5

L-Hyoscyamine analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Fórmula: C₁₇H₂₃NO₃

Pureza: (HPLC) ≥90%

Cor e Forma: Powder

Peso molecular: 289.38

Ref: 11-0669

Hyoscine Hydrobromide EP impurity A

CAS: 101-31-5

Fórmula: C₁₇H₂₃NO₃

Peso molecular: 289.4

Ref: ST-EA-CP-H16001

Hyoscyamine

CAS: 101-31-5

Cor e Forma: Neat

Ref: 61-FOR1699.00

(-)-Atropine

CAS: 101-31-5

Fórmula: C₁₇H₂₃NO₃

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 289.3694

Ref: IN-DA0003FJ

L-Hyoscyamine

CAS: 101-31-5

L-Hyoscyamine (Daturine) functions as a non-selective, competitive antagonist of muscarinic receptors, thereby inhibiting the parasympathetic activities.

Fórmula: C₁₇H₂₃NO₃

Pureza: 99.71% - 99.81%

Cor e Forma: White Crystalline Powder

Peso molecular: 289.37

Ref: TM-T0962

Scopolamine EP Impurity D (Hyoscine Hydrobromide EP Impurity A, Hyoscyamine, L-Atropine )

CAS: 101-31-5

Fórmula: C₁₇H₂₃NO₃

Cor e Forma: White To Off-White Solid

Peso molecular: 289.38

Ref: 4Z-S-0121

Hyoscyamine

CAS: 101-31-5

Fórmula: C₁₇H₂₃NO₃

Peso molecular: 289.38

Ref: 7W-GY3235

Hyoscyamine

CAS: 101-31-5

Fórmula: C₁₇H₂₃NO₃

Pureza: 95%~99%

Peso molecular: 289.375

Ref: BP-BP0749

Hyoscyamine

Produto Controlado

CAS: 101-31-5

Fórmula: C₁₇H₂₃NO₃

Cor e Forma: Neat

Peso molecular: 289.37

Ref: 04-C14270500

Hyoscyamine

Produto Controlado

CAS: 101-31-5

Fórmula: C₁₇H₂₃NO₃

Cor e Forma: Neat

Peso molecular: 289.37

Ref: 86-MM1699.00

L-Atropine-d5

CAS: 101-31-5

Fórmula: C₁₇H₁₈D₅NO₃

Peso molecular: 294.41

Ref: 4Z-A-151028

(-)-Hycosamine-d3

Produto Controlado

CAS: 101-31-5

Applications (-)-Hycosamine-d3, is the labeled analogue of (-)-Hycosamine (H674300), a natural compound that has inhibitory activity against cholinesterases.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Brunhofer, G. et al.: Bioorg. Med. Chem., 20, 6669 (2012);

Fórmula: C₁₇D₃H₂₀NO₃

Cor e Forma: Off-White

Peso molecular: 292.39

Ref: TR-H674302

(-)-Hycosamine

Produto Controlado

CAS: 101-31-5

Applications (-)-Hycosamine is a natural compound that has inhibitory activity against cholinesterases.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Brunhofer, G., et al.: Bioorg. Med. Chem., 20, 6669 (2012);

Fórmula: C₁₇H₂₃NO₃

Cor e Forma: Neat

Peso molecular: 289.37

Ref: TR-H674300

Hyoscyamine

CAS: 101-31-5

Hyoscyamine is a tropane alkaloid that is found in plants of the Solanaceae family, such as henbane and jimson weed. It has been used for centuries to treat gastrointestinal disorders, spastic colon, urinary incontinence, and other conditions. The drug works by inhibiting the release of acetylcholine from nerve endings at synapses in the brain and along the gastrointestinal tract. Inhibition of acetylcholine release leads to an increase in parasympathetic activity which results in decreased motility and increased secretions. Hyoscyamine inhibits epoxidase activity, which may be associated with its anti-inflammatory properties. This drug also has transcriptional regulation effects on genes related to growth, development, and reproduction; it inhibits the synthesis of proteins that regulate cell growth and division. Scopolamine is a derivative of hyoscyamine that has been used as a sedative or preoperative medication to reduce saliva production and decrease bronchial

Fórmula: C₁₇H₂₃NO₃

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 289.37 g/mol

Ref: 3D-FH36337

Scopolamine EP Impurity D (Hyoscine Hydrobromide EP Impurity A, Hyoscyamine, L-Atropine )

CAS: 101-31-5

Fórmula: C₁₇H₂₃NO₃

Peso molecular: 289.38

Ref: ST-EA-CP-S114019