CAS 1011641-78-3

D34-919

Sinónimos:

• D34-919

D34-919

CAS: 1011641-78-3

D34-919 is a potent inhibitor of the ALDH1A3-PKM2 interaction, effectively inhibiting the ALDH1A3-mediated tetramerization enhancement of PKM2. Treatment mediated by D34-919 both in vitro and in vivo enhances and restores apoptosis and sensitivity in glioblastoma (GBM) cells induced by radiochemotherapy.

Fórmula: C₂₂H₂₇N₅OS

Peso molecular: 409.55

Ref: TM-T201370