CAS 102040-03-9

Tubeimoside I

Descrição:

Tubeimoside I é um composto natural classificado como uma saponina triterpenoide, extraído principalmente da espécie vegetal *Tubersis* da família Liliaceae. É conhecido por sua complexa estrutura molecular, que tipicamente inclui uma espinha dorsal semelhante a um esteroide com vários moieties de açúcar anexados, contribuindo para sua atividade biológica. Tubeimoside I exibe uma gama de propriedades farmacológicas, incluindo efeitos anti-inflamatórios, anti-tumorais e imunomoduladores, tornando-se um assunto de interesse na química medicinal e farmacologia. O composto tem sido estudado por suas potenciais aplicações terapêuticas, particularmente no tratamento do câncer e na modulação do sistema imunológico. Seu mecanismo de ação muitas vezes envolve a indução de apoptose em células cancerosas e a inibição de citocinas pró-inflamatórias. Além disso, a solubilidade e estabilidade de Tubeimoside I em sistemas biológicos são fatores importantes que influenciam sua biodisponibilidade e eficácia. À medida que a pesquisa avança, mais insights sobre sua farmacocinética e potenciais efeitos colaterais são essenciais para avaliar sua segurança e eficácia em aplicações clínicas.

Fórmula: C₆₃H₉₈O₂₉

InChI: InChI=1/C65H102O29/c1-27-45-47(90-51-42(79)36(73)30(70)23-84-51)44(81)53(86-27)91-48-37(74)31(71)24-85-54(48)94-56(82)65-17-15-57(2,3)25-62(65,8)34-12-14-64(10)61(7)20-29(69)50(59(5,26-67)33(61)11-13-63(64,9)60(34,6)16-18-65)93-55-49(40(77)38(75)32(22-66)87-55)92-52-43(80)39(76)41(78)46(89-52)28(68)19-58(4,83)21-35(72)88-45/h12,27,29-33,36-55,66-67,69-71,73-81,83H,11,13-26H2,1-10H3/t27-,29-,30+,31+,32+,33+,36-,37-,38+,39-,40-,41+,42+,43+,44+,45-,46-,47-,48+,49+,50-,51-,52-,53-,54-,55-,58-,59-,60+,61-,62-,63-,64+,65+/m0/s1

Chave InChI: InChIKey=MCPFEAJYKIXPQF-DXZAWUHFSA-N

SMILES: O=C1[C@]23[C@](C=4[C@@](C)(CC2)[C@@]5(C)[C@](CC4)([C@]6(C)[C@@](CC5)([C@@](CO)(C)[C@]([C@@H](O)C6)(O[C@]7([C@](O[C@]8([C@H](O)[C@@H](O)[C@](CO8)(OC(=O)C[C@](C)(O)CC(=O)O[C@@]9([C@@H](O[C@H]%10[C@H](O)[C@@H](O)[C@H](O)CO%10)[C@@H](O)[C@](O[C@]%11([C@](O1)(OC[C@H](O)[C@@H]%11O)[H])[H])(O[C@H]9C)[H])[H])[H])[H])([C@@H](O)[C@H](O)[C@@H](CO)O7)[H])[H])[H])[H])[H])(CC(C)(C)CC3)[H]

Sinónimos:

• (1S,4S,7R,8S,9R,11S,13S,14S,18S,21R,22R,23S,24R,25R,27R,28S,29S,30R,32R,34R,35S,37S,38S,41R,42R,46S,53S,54R,56S,57R)-7,8,18,22,23,24,28,29,35,57-decahydroxy-30,54-bis(hydroxymethyl)-13,18,37,41,42,46,48,48,53,54-decamethyl-56-{[(2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl]oxy}-3,5,10,12,15,26,31,33,55-nonaoxadecacyclo[39.9.3.2~11,14~.1~21,25~.1~34,38~.0~1,46~.0~4,9~.0~27,32~.0~37,42~.0~45,53~]heptapentacont-44-ene-2,16,20-trione (non-preferred name)
• Lobatoside H
• Olean-12-en-28-oic acid, 3-[[2-O-[4-O-(4-carboxy-3-hydroxy-3-methyl-1-oxobutyl)-α-<span class="text-smallcaps">L</smallcap>-arabinopyranosyl]-β-<smallcap>D</smallcap>-glucopyranosyl]oxy]-2,23-dihydroxy-, 28-(O-β-<smallcap>D</smallcap>-xylopyranosyl-(1→3)-O-6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl-(1→2)-α-<smallcap>L</span>-arabinopyranosyl) ester, intramol. ester, [2β,3β(S),4α]-
• Olean-12-en-28-oic acid, 3-[[2-O-[4-O-[(3S)-4-carboxy-3-hydroxy-3-methyl-1-oxobutyl]-α-<span class="text-smallcaps">L</smallcap>-arabinopyranosyl]-β-<smallcap>D</smallcap>-glucopyranosyl]oxy]-2,23-dihydroxy-, 28-(O-β-<smallcap>D</smallcap>-xylopyranosyl-(1→3)-O-6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl-(1→2)-α-<smallcap>L</span>-arabinopyranosyl) ester, intramol. 4′′(3)→4′′(28)-ester, (2β,3β,4α)-
• Tubeimoside 1
• Tubeimoside I
• Tubelmosidea
• Tubemoside A
• Tuberimoside 1
• hydroxy-3-methyl-1-oxobutyl)-α-L-arabinopyra
• nosyl]-β-D-glucopyranosyl]oxy]-2,23-dihydroxy-,28-(O-β-D-xylopyranosyl-(1→3)-O-6-deoxy-α-L-mannopyranosyl-(1→2)-α-L-arabinopyranosyl)ester, intramol. ester, [2β,3β(S),4α]-
• Olean-12-en-28-oic acid, 3-[[2-O-[4-O-(4-carboxy-3-hydroxy-3-methyl-1-oxobutyl)-α-L-arabinopyranosyl]-β-D-glucopyranosyl]oxy]-2,23-dihydroxy-, 28-(O-β-D-xylopyranosyl-(1→3)-O-6-deoxy-α-L-mannopyranosyl-(1→2)-α-L-arabinopyranosyl) ester, intramol. ester, [2β,3β(S),4α]-
• Olean-12-en-28-oic acid, 3-[[2-O-[4-O-[(3S)-4-carboxy-3-hydroxy-3-methyl-1-oxobutyl]-α-L-arabinopyranosyl]-β-D-glucopyranosyl]oxy]-2,23-dihydroxy-, 28-(O-β-D-xylopyranosyl-(1→3)-O-6-deoxy-α-L-mannopyranosyl-(1→2)-α-L-arabinopyranosyl) ester, intramol. 4′′(3)→4′′(28)-ester, (2β,3β,4α)-
• Tubeimoside A
• TubeimosideⅠ
• TUBEIMOSIDE I (RG)
• 2)-a-L-arabinopyranosyl) ester, intramo
• Olean-12-en-28-oicacid, 3-[[2-O-[4-O-[(3S)-4-carboxy-3-hydroxy-3-methyl-1-oxobutyl]-a-L-arabinopyranosyl]-b-D-glucopyranosyl]oxy]-2,23-dihydroxy-,28-(O-b-D-xylopyranosyl-(1&reg
• Tubeimoside Ⅰ,HPLC≥98%
• 3)-O-6-deoxy-a-L-mannopyranosyl-(1&reg
• Olean-12-en-28-oicacid, 3-[[2-O-[4-O-(4-carboxy-3-

Olean-12-en-28-oic acid, 3-[[2-O-[4-O-[(3S)-4-carboxy-3-hydroxy-3-methyl-1-oxobutyl]-α-L-arabinopyranosyl]-β-D-glucopyranosyl]oxy]-2,23-dihydroxy-, 28-(O-β-D-xylopyranosyl-(1→3)-O-6-deoxy-α-L-mannopyranosyl-(1→2)-α-L-arabinopyranosyl) ester, intramol. 4''(3)→4''(28)-ester, (2β,3β,4α)-

CAS: 102040-03-9

Fórmula: C₆₃H₉₈O₂₉

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 1319.4348

Ref: IN-DA0006G7

Tubeimoside I

CAS: 102040-03-9

Tubeimoside I

Pureza: ≥98%

Peso molecular: 1319.43g/mol

Ref: 54-BUP00154

Tubeimoside

CAS: 102040-03-9

Fórmula: C₆₃H₉₈O₂₉

Peso molecular: 1319.43

Ref: 7W-GC0143

Tubeimoside I

CAS: 102040-03-9

Fórmula: C₆₃H₉₈O₂₉

Pureza: 95%~99%

Peso molecular: 1319.45

Ref: BP-BP1415

Tubeimoside I

CAS: 102040-03-9

Tubeimoside I (Tubeimoside-1)(Lobatoside-H) is an extract from Chinese herbal medicine Bolbostemma paniculatum (MAXIM).

Fórmula: C₆₃H₉₈O₂₉

Pureza: 98.89% - 99.94%

Cor e Forma: Solid

Peso molecular: 1319.43

Ref: TM-T2715

Tubeimoside i

CAS: 102040-03-9

Natural glycoside

Fórmula: C₆₃H₉₈O₂₉

Pureza: ≥ 95.0 % (HPLC)

Peso molecular: 1319.46

Ref: 5G-80550

Tubeimoside A

Produto Controlado

CAS: 102040-03-9

Applications Tubeimoside A is an extract of tubeimoside, the bulb of Bolbostemma paniculatum, and is used in traditional Chinese medicine to treat tumors and to detoxify.
References Xu, Y. et al.: Chin. J. Canc. Res., 25, 312 (2013); Zhao, H. et al.: Chin. Sci. Bull., 33, 878 (2013);

Fórmula: C₆₃H₉₈O₂₉

Cor e Forma: Neat

Peso molecular: 1319.43

Ref: TR-T897030

Tubeimoside

CAS: 102040-03-9

Tubeimoside is a saponin-based compound, which is derived from the tuber of the Bolbostemma paniculatum plant, a member of the Cucurbitaceae family. Known for its unique mode of action, Tubeimoside exerts its effects by disrupting cellular membranes and inducing apoptosis in cancer cells. This mechanism makes it a potent agent in targeting malignant cells, primarily by activating caspase pathways and generating reactive oxygen species (ROS) that lead to programmed cell death.

Fórmula: C₆₃H₉₈O₂₉

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 1,319.48 g/mol

Ref: 3D-OT08921