CAS 10212-20-1

4-Amino-1-[(2R,3R,4R,5R)-3-flúor-4-hidroxi-5-(hidroximetil)oxolan-2-il]pirimidin-2-ona

Descrição:

4-Amino-1-[(2R,3R,4R,5R)-3-flúor-4-hidroxi-5-(hidroximetil)oxolan-2-il]pirimidin-2-ona, com número CAS 10212-20-1, é um composto químico caracterizado por sua estrutura de moiety de pirimidina e açúcar. Este composto apresenta um grupo amino na posição 4 do anel de pirimidina, o que contribui para sua potencial atividade biológica. A presença de um átomo de flúor e grupos hidroxila no moiety de açúcar aumenta sua solubilidade e reatividade, tornando-o de interesse na química medicinal, particularmente no desenvolvimento de agentes antivirais ou anticancerígenos. A estereoquímica indicada pela configuração (2R,3R,4R,5R) sugere arranjos espaciais específicos que podem influenciar as interações do composto com alvos biológicos. Além disso, o grupo hidroximetila pode desempenhar um papel na ligação de hidrogênio, afetando ainda mais suas propriedades farmacológicas. No geral, este composto exemplifica a complexidade e diversidade das estruturas químicas que podem ser exploradas para aplicações terapêuticas.

Fórmula: C₉H₁₂FN₃O₄

InChI: InChI=1/C9H12FN3O4/c10-6-7(15)4(3-14)17-8(6)13-2-1-5(11)12-9(13)16/h1-2,4,6-8,14-15H,3H2,(H2,11,12,16)/t4-,6?,7-,8-/m1/s1

Chave InChI: InChIKey=NVZFZMCNALTPBY-XVFCMESISA-N

SMILES: F[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)N=C(N)C=C2

Sinónimos:

• 2'-Deoxy-2'-Fluorocytidine
• 2'-Deoxy-2'-fluoro-D-cytidine
• 2'-Fc
• 2'-Fluoro-2'-Deoxycytidine
• 2'-Fluoro-D-Cytidine
• 2′-Fluoro-2′-deoxy-β-<span class="text-smallcaps">D</span>-ribofuranosylcytosine
• 4-Amino-1-((2R,3R,4R,5R)-3-Fluoro-4-Hydroxy-5-Hydroxymethyl-Tetrahydro-Furan-2-Yl)-1H-Pyrimidin-2-One
• 4-Amino-1-[3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
• 4-amino-1-(2-deoxy-2-fluoropentofuranosyl)pyrimidin-2(1H)-one
• Cytidine, 2′-deoxy-2′-fluoro-
• NSC 529432
• 2′-Fluoro-2′-deoxy-β-D-ribofuranosylcytosine
• 2'-DEOXY-2'-FLUOROCYTIDINE(2'-FLUORO-2'-DEOXYCYTIDINE, 2'-FC)
• 2'-Deoxy-2'-fluorocytidine Hydrate
• 2''-DEOXY-2''-FLUOROCYTIDINE,99+%
• RO-8013
• 2'-FdC
• 4-amino-1-[(2r,3r,4r,5r)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
• 1-(2-Fluoro-2-deoxy-β-D-arabinofuranosyl)cytosine

2'-Deoxy-2'-fluorocytidine

CAS: 10212-20-1

Fórmula: C₉H₁₂FN₃O₄

Pureza: >98.0%(T)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 245.21

Ref: 3B-D3614

2'-Fluoro-2'-deoxycytidine, 99%

CAS: 10212-20-1

2'-Fluoro-2'-deoxycytidine is a potent inhibitor of the subgenomic hepatitis C virus replicon in Huh-7 cells. 2'-Fluoro-2'-deoxycytidine has been shown to inhibit Borna Disease virus replication and spread. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product

Fórmula: C₉H₁₂FN₃O₄

Pureza: 99%

Peso molecular: 245.21

Ref: 02-J65632

Cytidine, 2'-deoxy-2'-fluoro-

CAS: 10212-20-1

Fórmula: C₉H₁₂FN₃O₄

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 245.2077

Ref: IN-DA0006OP

2'-Deoxy-2'-fluorocytidine

CAS: 10212-20-1

2'-Deoxy-2'-fluorocytidine

Pureza: ≥98%

Peso molecular: 245.21g/mol

Ref: 54-BUP17473

4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

CAS: 10212-20-1

4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

Pureza: 98%

Peso molecular: 245.21g/mol

Ref: 54-PC105247

2''-Fluoro-2''-deoxycytidine

CAS: 10212-20-1

Fórmula: C₉H₁₂FN₃O₄

Pureza: ≥ 98.0%

Cor e Forma: White to off-white powder

Peso molecular: 245.21

Ref: 7W-GE0680

2’-Deoxy-2’-fluoro Cytidine

CAS: 10212-20-1

Fórmula: C₉H₁₂FN₃O₄

Peso molecular: 245.21

Ref: 4Z-C-4512

2'-Deoxy-2'-fluorocytidine

CAS: 10212-20-1

2'-Deoxy-2'-fluorocytidine is an nucleoside analog and inhibits of Crimean-Congo hemorrhagic fever virus (CCHFV) replication potently.

Fórmula: C₉H₁₂FN₃O₄

Pureza: 99.90%

Cor e Forma: White Or Almost White Crystalline Powder

Peso molecular: 245.21

Ref: TM-T38238

2'-Deoxy-2'-fluorocytidine

CAS: 10212-20-1

2'-Deoxy-2'-fluorocytidine is a nucleoside analog with the potential as an Crimean-Congo hemorrhagic fever virus antiviral

Fórmula: C₉H₁₂FN₃O₄

Pureza: Min. 98 Area-%

Cor e Forma: White Off-White Powder

Peso molecular: 245.21 g/mol

Ref: 3D-ND06189

2′-Deoxy-2′-fluorocytidine

CAS: 10212-20-1

Fórmula: C₉H₁₂FN₃O₄

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 245.21

Ref: 10-F211882

2’-Deoxy-2’-fluoro Cytidine

Produto Controlado

CAS: 10212-20-1

Applications 2'-Deoxy-2'-fluorocytidine is a potent inhibitor of the subgenomic hepatitis C virus replicon in Huh-7 cells. 2'-Deoxy-2'-fluorocytidine has been shown to inhibit Borna Disease virus replication and spread.
References Stuyver, L.J. et al.: Antimicrob. Agents Chemother., 48, 651 (2004); Bajramovic, J.J. et al.: Antiomicrob. Agents Chemother., 48, 1422 (2004);

Fórmula: C₉H₁₂FN₃O₄

Cor e Forma: Neat

Peso molecular: 245.21

Ref: TR-D232945

2\'-Deoxy-2\'-fluoro Cytidine

CAS: 10212-20-1

Fórmula: C₉H₁₂FN₃O₄

Peso molecular: 245.21

Ref: ST-EA-CP-C151034