CAS 1022895-92-6

Cilastatin Impurity 28

CAS: 1022895-92-6

Fórmula: C₁₅H₂₄ClNO₃

Peso molecular: 301.81

Ref: 4Z-C-136043

(2Z)​-7-​Chloro-​2-​[[[(1R)​-​2,​2-​dimethylcyclopropyl]​carbonyl]​amino]​-2-heptenoic Acid Ethyl Ester

Produto Controlado

CAS: 1022895-92-6, 1022895-93-7, 877758-94-6

Applications (2Z)​-7-​Chloro-​2-​[[[(1R)​-​2,​2-​dimethylcyclopropyl]​carbonyl]​amino]​-2-heptenoic Acid Ethyl Ester is an intermediate in the synthesis of (R,R)-Cilastatin (C441120), which is a derivative of Cilastatin (C441100), prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct.
References Finlay, K.R., et al.: Invest. Ophthalmol. Visual Sci., 24, 1147 (1983), Norrby, S.R., et al.: Antimicrob. Agents Chemother., 23, 300 (1983), Washburn, D.E., et al.: J. Antimicrob. Chemother., 12, 39 (1983),

Fórmula: C₁₅H₂₄ClNO₃

Cor e Forma: Neat

Peso molecular: 301.809

Ref: TR-C472205