CAS 10246-75-0

hidroxizina pamoato

Descrição:

hidroxizina pamoato é um medicamento utilizado principalmente por suas propriedades anti-histamínicas e ansiolíticas. É uma forma salina de hidroxizina, que é um anti-histamínico que pode aliviar os sintomas de alergias, ansiedade e náuseas. O sal pamoato melhora sua solubilidade e biodisponibilidade. hidroxizina pamoato é tipicamente administrado por via oral e é conhecido por seus efeitos sedativos, tornando-o útil no tratamento de transtornos de ansiedade e como pré-medicação para procedimentos cirúrgicos. O composto apresenta um peso molecular relativamente alto e é caracterizado por sua capacidade de atravessar a barreira hematoencefálica, contribuindo para seus efeitos no sistema nervoso central. É importante notar que hidroxizina pamoato pode causar efeitos colaterais como sonolência, boca seca e tontura. Assim como qualquer medicamento, deve ser usado sob a orientação de um profissional de saúde, considerando possíveis interações com outros medicamentos e fatores individuais do paciente.

Fórmula: C₂₃H₁₆O₆·C₂₁H₂₇ClN₂O₂

InChI: InChI=1S/C23H16O6.C21H27ClN2O2/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25/h1-10,24-25H,11H2,(H,26,27)(H,28,29);1-9,21,25H,10-17H2

Chave InChI: InChIKey=ASDOKGIIKXGMNB-UHFFFAOYSA-N

SMILES: C(C=1C2=C(C=C(C(O)=O)C1O)C=CC=C2)C=3C4=C(C=C(C(O)=O)C3O)C=CC=C4.C(N1CCN(CCOCCO)CC1)(C2=CC=C(Cl)C=C2)C3=CC=CC=C3

Sinónimos:

• 1-(p-Chloro-α-phenylbenzyl)-4-(2-hydroxyethoxyethyl)piperazine, pamoate
• 2-(2-(4-((4-Chlorophenyl)(Phenyl)Methyl)Piperazin-1-Yl)Ethoxy)Ethanol 4,4′-Methylenebis(3-Hydroxy-2-Naphthoate)
• 2-(2-{4-[(4-Chlorophenyl)(Phenyl)Methyl]Piperazin-1-Yl}Ethoxy)Ethanol
• 2-Naphthalenecarboxylic acid, 4,4′-methylenebis[3-hydroxy-, compd. with 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]ethanol (1:1)
• 2-Naphthoic acid, 4,4′-methylenebis[3-hydroxy-, compd. with 2-[2-[4-(p-chloro-α-phenylbenzyl)-1-piperazinyl]ethoxy]ethanol (1:1)
• 2-Naphthoic acid, 4,4′-methylenebis[3-hydroxy-, hydroxyzine salt
• 4,4'-Methanediylbis(3-Hydroxynaphthalene-2-Carboxylic Acid) - 2-(2-{4-[(4-Chlorophenyl)(Phenyl)Methyl]Piperazin-1-Yl}Ethoxy)Ethanol (1:1)
• Atarax P
• Equipose
• Ethanol, 2-[2-[4-(p-chloro-α-phenylbenzyl)-1-piperazinyl]ethoxy]-, 4,4′-methylenebis[3-hydroxy-2-naphthoate] (1:1) (salt)
• Ethanol, 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, 4,4′-methylenebis[3-hydroxy-2-naphthalenecarboxylate] (1:1)
• Hydroxyzine Embonate
• Hydroxyzyne pamoate
• Masmoran
• Paxisitil
• Paxistil
• Vistaril

Hydroxyzine Pamoate

CAS: 10246-75-0

Cor e Forma: Neat

Ref: 61-FOR3107.00

Hydroxyzine Pamoate

CAS: 10246-75-0

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

Fórmula: C₂₁H₂₇ClN₂O₂·C₂₃H₁₆O₆

Cor e Forma: Light Yellow Powder

Peso molecular: 763.27

Ref: 45-1334006

Hydroxyzine pamoate

CAS: 10246-75-0

Fórmula: C₄₄H₄₃ClN₂O₈

Pureza: 96%

Cor e Forma: Solid

Peso molecular: 763.2738

Ref: IN-DA007FBV

Hydroxyzine Pamoate

CAS: 10246-75-0

Hydroxyzine Pamoate (Bobsule) is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria and histamine-mediated pruritus.

Fórmula: C₄₄H₄₃ClN₂O₈

Pureza: 99.49%

Cor e Forma: Solid

Peso molecular: 763.27

Ref: TM-T0053

Hydroxyzine Pamoate

CAS: 10246-75-0

Hydroxyzine Pamoate

Pureza: ≥98%

Peso molecular: 763.27g/mol

Ref: 54-BUP15032

Hydroxyzine Pamoate

Produto Controlado

CAS: 10246-75-0

Fórmula: C₂₃H₁₆O₆·C₂₁H₂₇ClN₂O₂

Cor e Forma: Neat

Peso molecular: 763.27

Ref: 86-MM3107.00

Hydroxyzine pamoate

Produto Controlado

CAS: 10246-75-0

Hydroxyzine pamoate is a drug that belongs to the group of H1 antagonists. It is used for the treatment of allergic reactions, bowel disease, and infectious diseases. Hydroxyzine pamoate has been shown to have a low potency in animals and humans, with a high incidence of side effects. This drug may act by competing with histamine at the receptor sites on mast cells or basophils. The matrix effect of this drug is unclear. Hydroxyzine pamoate has been shown to inhibit protein synthesis in some bacteria and can be used as an analytical method for detecting histamine in human blood samples.

Fórmula: C₄₄H₄₃ClN₂O₈

Pureza: Min. 95%

Cor e Forma: White To Light (Or Pale) Yellow Solid

Peso molecular: 763.27 g/mol

Ref: 3D-FH171674

Hydroxyzine Pamoate

CAS: 10246-75-0

Applications Hydroxyzine Pamoate is an H1 receptor antagonist. Anxiolytic. Antihistaminic.
References De Bruyn, T. et al.: Mol. Pharm., 83, 1257 (2013); Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Tsau, J., et al.: Anal. Profiles Drug Subs., 7, 319 (1978)

Fórmula: C₂₃H₁₆O₆·C₂₁H₂₇ClN₂O₂

Cor e Forma: Neat

Peso molecular: 763.27

Ref: TR-H996505

Hydroxyzine Pamoate

CAS: 10246-75-0

Fórmula: C₂₁H₂₇ClN₂O₂C₂₃H₁₆O₆

Peso molecular: 374.9 : 388.4

Ref: ST-EA-CP-H11010