CAS 102625-64-9

Sulfeto de pantoprazol

Descrição:

Sulfeto de pantoprazol, com o número CAS 102625-64-9, é um composto químico que é um derivado do pantoprazol, um inibidor da bomba de prótons comumente usado para tratar a doença do refluxo gastroesofágico (DRGE) e outras condições relacionadas ao excesso de ácido estomacal. Este composto é caracterizado pelo seu grupo funcional sulfinila, que contribui para suas propriedades farmacológicas. Sulfeto de pantoprazol é tipicamente um sólido cristalino branco a off-white, exibindo baixa solubilidade em água, mas maior solubilidade em solventes orgânicos. É conhecido por sua estabilidade em condições ácidas, o que é essencial para sua função na inibição da secreção de ácido gástrico. O composto opera ligando-se irreversivelmente à bomba de prótons na mucosa do estômago, reduzindo assim a produção de ácido. Sua farmacocinética envolve rápida absorção e metabolismo, principalmente no fígado, levando a seus metabólitos ativos. Assim como muitos produtos farmacêuticos, a segurança e a eficácia são primordiais, e Sulfeto de pantoprazol está sujeito a escrutínio regulatório para garantir que atenda aos padrões de saúde para uso terapêutico.

Fórmula: C₁₆H₁₅F₂N₃O₃S

InChI: InChI=1/C16H15F2N3O3S/c1-22-13-5-6-19-12(14(13)23-2)8-25-16-20-10-4-3-9(24-15(17)18)7-11(10)21-16/h3-7,15H,8H2,1-2H3,(H,20,21)

Chave InChI: InChIKey=UKILEIRWOYBGEJ-UHFFFAOYSA-N

SMILES: S(CC1=C(OC)C(OC)=CC=N1)C=2NC=3C(N2)=CC(OC(F)F)=CC3

Sinónimos:

• 1H-Benzimidazole, 5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-
• 1H-Benzimidazole, 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-
• 5-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridyl)methyl]thio]-1H-benzimidazole
• 5-(Difluoromethoxy)-2-{[( 3,4 Dimethoxypyridin-2-yl) methyl] thio}-1H-benzimidazolee
• 5-Difluoromethoxy-2-[(3,4-methoxy-2-pyridinylmethyl thio)-1H-benzimidozole
• 5-Diflyoromethoxy-2-[(3,4-dimethoxy-2-pyridinyl)methyl]thio-1H-benzimidazole
• 6-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-1H-benzimidazole
• 6-(difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole
• H 258/28
• Pantoprazole sulfide
• Pantoprazole thioether
• 5-Difluoromethoxy-2-{[(3,4-dimethoxy-2-pyridinyl)methyl]thio}-1H-benzimidazole
• 5-(Difluoromethoxy)-2[[(3,4-dimethoxy-2-pyridinyl)methyl]-thio]-1H-benzimidazole
• 5-(Difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]sulphanyl}-1H-benzimidazole
• 5-DIFLUOROMETHOXY-2-[(3,4-DIMETHOXY-2-PYRIDINYL)METHYL] THIO-1H-BENZIMIDAZOLE =98%
• 5-(Difluoromethoxy)-2-{[3,4-di
• 5-(DIFLUOROMETHOXY)-2-{[3,4-DIMETHOXY-2-PYRIDINYL)METHYL]THIO}IH-BENZIMIDAZOLE
• 5-DIFLUORMETHOXY-2[(3,4-DIMETHOXY-2-PRIDIXY)METHYLTHIO]-1H-BENZIMIDAZOLE
• 5-(Difluoromethoxy)-2-{[(3,4-dimethoxy-2-pyridinyl)-methyl]-thio}-1H-benzim
• 5-Difluoromethoxy-2-(((3,4-Dimethoxy-2-pyridinyl)methyl)thio)-1H-Benzimidazole (Pantaprazole intermediate)
• 5-Difluoromethoxy-2-{[(3,4-dim
• 5-(DIFLUOROMETHOXY)-2-[[3,4-DIMETHOXY-2-PYRIDINYL)-METHYL]-THIO]-1H-BENZIMIDAZOLE (PANTOPRAZOLE SULPHIDE COMPOUND)
• 5-Difluoromethoxy-2-(3,4-dimethoxy-pyridin-2-ylmethylsulfanyl)-1H-benzoimidazole
• 5-(Difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]thio}-1H-benzimidazole

Pantoprazole Sulfide

CAS: 102625-64-9

Fórmula: C₁₆H₁₅F₂N₃O₃S

Pureza: >98.0%(T)(HPLC)

Cor e Forma: Light orange to Light red powder to crystal

Peso molecular: 367.37

Ref: 3B-P2066

Pantoprazole Related Compound B (5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-1H-benzimidazole)

CAS: 102625-64-9

Compounds containing an unfused pyridine ring in the structure, nesoi

Fórmula: C₁₆H₁₅F₂N₃O₃S

Cor e Forma: Off-White Light Brown Crystalline Powder

Peso molecular: 367.08022

Ref: 45-1494910

1H-Benzimidazole, 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-

CAS: 102625-64-9

Fórmula: C₁₆H₁₅F₂N₃O₃S

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 367.3704

Ref: IN-DA0007YM

Pantoprazole EP Impurity B (Pantoprazole USP Related Compound B, Pantoprazole Sulfide)

CAS: 102625-64-9

Fórmula: C₁₆H₁₅F₂N₃O₃S

Cor e Forma: Off-White Solid

Peso molecular: 367.37

Ref: 4Z-P-0111

5-(Difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]thio}-1H-benzimidazole

CAS: 102625-64-9

5-(Difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]thio}-1H-benzimidazole

Pureza: 98%

Peso molecular: 367.37g/mol

Ref: 54-PC3237

Pantoprazole EP Impurity B

Produto Controlado

CAS: 102625-64-9

Fórmula: C₁₆H₁₅F₂N₃O₃S

Cor e Forma: Neat

Peso molecular: 367.37

Ref: 86-MM0099.03

Pantoprazole Sulfide

CAS: 102625-64-9

Pantoprazole sulfide, a metabolite of pantoprazole, is formed by CYP2C19 and CYP3A4 enzymes.

Fórmula: C₁₆H₁₅F₂N₃O₃S

Cor e Forma: Solid

Peso molecular: 367.37

Ref: TM-T37247

Pantoprazole EP Impurity B-d6 (Pantoprazole USP Related Compound B-d6, Pantoprazole Sulfide-d6)

CAS: 102625-64-9

Fórmula: C₁₆H₉D₆F₂N₃O₃S

Peso molecular: 373.41

Ref: 4Z-P-0185

5-Difluoromethoxy-2-[(3,4-dimethoxy-2-pyridinyl)methyl]thio-1H-benzimidazole

CAS: 102625-64-9

Pureza: 95.0%

Peso molecular: 367.3699951171875

Ref: 10-F049541

Pantoprazole EP Impurity B

CAS: 102625-64-9

Fórmula: C₁₆H₁₅F₂N₃O₃S

Peso molecular: 367.37

Ref: ST-EA-CP-P15002

Pantoprazole Sulfide

CAS: 102625-64-9

Impurity Pantoprazole EP Impurity B/ Pantoprazole USP Related Compound B
Applications Pantoprazole Sulfide (Pantoprazole EP Impurity B) is a metabolite of Pantoprazole (P183000), an antiulcerative, gastric pump inhibitor.

Fórmula: C₁₆H₁₅F₂N₃O₃S

Cor e Forma: Neat

Peso molecular: 367.37

Ref: TR-P183020

Pantoprazole sulphide

CAS: 102625-64-9

Pantoprazole sulphide is a benzimidazole derivative that has been synthesized in an asymmetric synthesis. The purified compound was characterized by its nmr spectra, which showed the presence of the carboethoxy group and the chromatographic method. The compound belongs to a family of inhibitors known as benzimidazole derivatives and has shown inhibitory activity against a number of bacterial species including Staphylococcus aureus, Clostridium perfringens, and Mycobacterium tuberculosis. Pantoprazole sulphide has been used as an inhibitor to treat gastric acid pump disorders such as Zollinger-Ellison syndrome. It is also used for treating pathological conditions such as duodenal ulcers or gastroesophageal reflux disease.

Fórmula: C₁₆H₁₅F₂N₃O₃S

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 367.37 g/mol

Ref: 3D-ID57911