CAS 102772-66-7

Piridínio, 1-[[(6R,7R)-7-[[(2Z)-2-(2-amino-4-tiazolil)-2-[[2-(1,1-dimetiletoxil)-1,1-dimetil-2-oxoetoxi]imino]acetil]amino]-2-carboxi-8-oxo-5-tia-1-azabiciclo[4.2.0]oct-2-en-3-il]metil]-, sal interna

Descrição:

Piridínio, 1-[[(6R,7R)-7-[[(2Z)-2-(2-amino-4-tiazolil)-2-[[2-(1,1-dimetiletoxil)-1,1-dimetil-2-oxoetoxi]imino]acetil]amino]-2-carboxi-8-oxo-5-tia-1-azabiciclo[4.2.0]oct-2-en-3-il]metil]-, sal interna, identificado pelo número CAS 102772-66-7, é um composto orgânico complexo caracterizado por sua intrincada estrutura molecular, que inclui um moiety de piridínio e múltiplos grupos funcionais como tiazol, ácido carboxílico e funcionalidades de amida. Este composto é tipicamente solúvel em solventes polares devido à sua natureza iônica, que surge da formação de sal interno. Sua estrutura sugere uma potencial atividade biológica, possivelmente como agente antimicrobiano ou terapêutico, dada a presença de tiazol e derivados de aminoácidos. A estereoquímica indicada pela configuração (6R,7R) pode influenciar suas interações biológicas e farmacocinética. No geral, este composto exemplifica a diversidade da química orgânica sintética, particularmente no design de moléculas com potenciais aplicações farmacêuticas.

Fórmula: C₂₆H₃₀N₆O₇S₂

InChI: InChI=1S/C26H30N6O7S2/c1-25(2,3)38-23(37)26(4,5)39-30-16(15-13-41-24(27)28-15)19(33)29-17-20(34)32-18(22(35)36)14(12-40-21(17)32)11-31-9-7-6-8-10-31/h6-10,13,17,21H,11-12H2,1-5H3,(H3-,27,28,29,33,35,36)/b30-16-/t17-,21-/m1/s1

Chave InChI: InChIKey=KRTGQDGIPNXUGP-ZLQBWVSZSA-N

SMILES: C([O-])(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC(C(OC(C)(C)C)=O)(C)C)/C3=CSC(N)=N3)=O)C2=O)(SCC1C[N+]=4C=CC=CC4)[H]

Sinónimos:

• Pyridinium, 1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)[[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt
• Pyridinium, 1-[[(6R,7R)-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-[[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt
• Ceftazidime tert-butyl ester
• Pyridinium, 1-[[7-[[(2-amino-4-thiazolyl)[[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt, [6R-[6α,7β(Z)]]-
• 1-[[(6R,7R)-7-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-[[2-(1,1-diMethylethoxy)-1,1-diMethyl-2-oxoethoxy]iMino]acetyl]aMino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]Methyl]pyridiniuM Inner Salt
• Ceftazidime Impurity E (EP) (Ceftazidime t-Butyl Ester )
• Ceftazidime Ep Impurity E
• CeftazidiMe t-Butyl Ester
• Ceftazidime N-2 Intermediate
• Ceftazidime impurity 5/Ceftazidime EP Impurity E/(6R,7R)-7-[[(2Z)-2-(2-aminothiazol-4-yl)-2-[[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]imino]acetyl]amino]-8-oxo-3-[(1-pyridinio)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• Ceftazidime Impurity 5(Ceftazidime EP Impurity E)
• (6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(((1-(tert-butoxy)-2-methyl-1-oxopropan-2-yl)oxy)imino)acetamido)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• Ceftazidime Impurity D(EP)

Ceftazidime T-Butyl Ester

CAS: 102772-66-7

Ceftazidime T-Butyl Ester

Pureza: 99%

Peso molecular: 602.68g/mol

Ref: 54-OR1027176

Ceftazidime EP Impurity E

CAS: 102772-66-7

Fórmula: C₂₆H₃₀N₆O₇S₂

Cor e Forma: White To Off-White Solid

Peso molecular: 602.68

Ref: 4Z-C-10504

Ceftazidime t-Butyl Ester

Produto Controlado

CAS: 102772-66-7

Impurity Ceftazidime EP Impurity E
Applications Ceftazidime t-Butyl Ester (Ceftazidime EP Impurity E) Ceftazidime t-Butyl ester is an impurity of Ceftazidime (C244100). Ceftazidime impurity C.
References Miyake, A., et al.: Antimicrob. Agents Chemother., 486, 182 (1989), Seibert, G., et al.: Arzneim.-Forsch., 33, 1084 (1983),

Fórmula: C₂₆H₃₀N₆O₇S₂

Cor e Forma: Neat

Peso molecular: 602.68

Ref: TR-C244115

Ceftazidime t-butyl ester

CAS: 102772-66-7

Ceftazidime t-butyl ester is a prodrug of ceftazidime. It is a crystalline, stable form of the drug that can be dissolved in an organic solvent. Ceftazidime t-butyl ester has an average UV detection wavelength with a linear range of 200-600 nm and can be detected at a wavelength of 220 nm. This drug is used to treat infections caused by bacteria, including those that are resistant to other antibiotics, such as penicillin or ampicillin. Ceftazidime t-butyl ester has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex.

Fórmula: C₂₆H₃₀N₆O₇S₂

Pureza: Min. 95%

Peso molecular: 602.68 g/mol

Ref: 3D-IC19872

Ceftazidime EP Impurity E

CAS: 102772-66-7

Fórmula: C₂₆H₃₀N₆O₇S₂

Peso molecular: 602.68

Ref: ST-EA-CP-C12005