CAS 103213-32-7

N-[(9H-Fluoren-9-ilmetoxi)carbonil]-S-(trifenilmetil)-L-cisteína

Descrição:

N-[(9H-Fluoren-9-ilmetoxi)carbonil]-S-(trifenilmetil)-L-cisteína, comumente referido como Fmoc-Cys(Trt)-OH, é um derivado do aminoácido cisteína, modificado para uso na síntese de peptídeos. Este composto apresenta um grupo protetor fluorenilmetoxicarbonila (Fmoc), que é amplamente utilizado na síntese de peptídeos em fase sólida devido à sua estabilidade em condições básicas e facilidade de remoção em condições ácidas. O grupo triphenylmethyl (Trt) serve como um grupo protetor para a cadeia lateral tiol da cisteína, proporcionando estabilidade e evitando reações indesejadas durante a síntese. A presença desses grupos protetores permite a deproteção seletiva em estágios específicos da montagem de peptídeos. Fmoc-Cys(Trt)-OH é tipicamente um sólido branco a off-white e é solúvel em solventes orgânicos como dimetilformamida (DMF) e dimetilsulfóxido (DMSO). Sua aplicação é principalmente na síntese de peptídeos e proteínas, particularmente aqueles que requerem a incorporação de resíduos de cisteína, que são cruciais para a formação de ligações dissulfeto e manutenção da integridade estrutural nas proteínas.

Fórmula: C₃₇H₃₁NO₄S

InChI: InChI=1S/C37H31NO4S/c39-35(40)34(38-36(41)42-24-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33)25-43-37(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28/h1-23,33-34H,24-25H2,(H,38,41)(H,39,40)/t34-/m0/s1

Chave InChI: InChIKey=KLBPUVPNPAJWHZ-UMSFTDKQSA-N

SMILES: C(SC[C@H](NC(OCC1C=2C(C=3C1=CC=CC3)=CC=CC2)=O)C(O)=O)(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6

Sinónimos:

• (2R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-tritylsulfanylpropanoic acid
• (2R)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-(tritylsulfanyl)propanoate
• (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-(tritylsulfanyl)propanoate
• 2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-(tritylthio)propanoic acid
• 3: PN: US20040265921 PAGE: 4 claimed protein
• <span class="text-smallcaps">L</span>-Cysteine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)-
• Fmoc-Cys(Trt)-OH
• Fmoc-L-Cys(Trt)-OH
• Fmoc-L-Cysteine(Trityl)
• N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-trityl-<span class="text-smallcaps">L</span>-cysteine
• N-(9-Fluorenyl Methoxy Carbonyl)-S-Trityl-L-Cysteine
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)-<span class="text-smallcaps">L</span>-cysteine
• N-[(9H-fluoren-9-ylmethoxy)carbonyl]-S-trityl-D-cysteine
• N-[(9H-fluoren-9-ylmethoxy)carbonyl]-S-trityl-L-cysteine
• N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-trityl-L-cysteine
• L-Cysteine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)-

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)-L-cysteine

CAS: 103213-32-7

Fórmula: C₃₇H₃₁NO₄S

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 585.72

Ref: 3B-F0652

N-Fmoc-S-trityl-L-cysteine, 95%

CAS: 103213-32-7

It is potentially useful for proteomics studies, and solid phase peptide synthesis techniques. Cysteine is versatile amino acid involved with many biological processes, including the formation of disulfide bonds - a critical component of protein structure. This compound could be useful as an unusual

Fórmula: C₃₇H₃₁NO₄S

Pureza: 95%

Cor e Forma: White to pale cream, Powder

Peso molecular: 585.71

Ref: 02-H27363

Fmoc-Cys(Trt)-OH

CAS: 103213-32-7

Standard derivative for Fmoc-SPPS. Educt for obtaining S-alkylated cysteines via thiol-ene reaction.

Fórmula: C₃₇H₃₁NO₄S

Pureza: 99.9421%

Cor e Forma: White

Peso molecular: 585.72

Ref: 01-4007272

Fmoc-Cys(Trt)-OH

CAS: 103213-32-7

Fórmula: C₃₇H₃₁NO₄S

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 585.7113

Ref: IN-DA0038CZ

Fmoc-Cys(Trt)-OH

CAS: 103213-32-7

Fórmula: C₃₇H₃₁NO₄S

Pureza: ≥ 99.0%

Cor e Forma: White to almost white powder

Peso molecular: 585.71

Ref: 7W-GM8515

S-Trityl-L-cysteine, N-FMOC protected

CAS: 103213-32-7

S-Trityl-L-cysteine, N-FMOC protected

Fórmula: C₃₇H₃₁NO₄S

Pureza: 98%

Cor e Forma: white solid

Peso molecular: 585.71g/mol

Ref: 54-OR0492

Fmoc-Cys(Trt)-OH

CAS: 103213-32-7

Fmoc-Cys(Trt)-OH, with catalog number T67555 and CAS number 103213-32-7, is a valuable organic compound for life sciences research.

Fórmula: C₃₇H₃₁NO₄S

Cor e Forma: Solid

Peso molecular: 585.72

Ref: TM-T67555

Fmoc-Cys(Trt)-OH

CAS: 103213-32-7

M03395 - Fmoc-Cys(Trt)-OH

Fórmula: C₃₇H₃₁NO₄S

Pureza: 97%

Cor e Forma: Solid, Powder or Crystalline Powder

Peso molecular: 585.72

Ref: 10-M03395

S-Trityl-N-Fomc_L-Cysteine

CAS: 103213-32-7

Fórmula: C₃₇H₃₁NO₄S

Peso molecular: 585.72

Ref: 4Z-C-7721

Fmoc-Cys(Trt)-OH

CAS: 103213-32-7

Fmoc-Cys(Trt)-OH is a cyclic peptide that has potent antitumor activity. It binds to albumin and inhibits protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. Fmoc-Cys(Trt)-OH has been shown to be effective against cancer cells in vitro and in vivo. Fmoc-Cys(Trt)-OH also binds the plasma glucose, which may be due to its ability to impede insulin release from the pancreas. This compound is synthesized by a stepwise light-induced solid-phase synthesis with trifluoroacetic acid as a solvent.

Fórmula: C₃₇H₃₁NO₄S

Pureza: Min. 98 Area-%

Cor e Forma: White Powder

Peso molecular: 585.71 g/mol

Ref: 3D-FF15783

Fmoc-Cys(Trt)-OH

CAS: 103213-32-7

Fmoc-Cys(Trt)-OH is a chemical compound that has been shown to have potent antitumor activity in mice. It is synthesized by the stepwise addition of amino acids to the resin-bound Cys residue in the presence of trifluoroacetic acid and a coupling agent such as EDC. This reaction produces a functional protein with an amide bond. The acetylcholine receptor binding properties of Fmoc-Cys(Trt)-OH are due to its ability to form a disulfide bond with cysteine residues on the receptor.

Fórmula: C₃₇H₃₁NO₄S

Pureza: Min. 98.0 Area-%

Peso molecular: 585.71 g/mol

Ref: 3D-FLC-1718-PI

N-(((9H-Fluoren-9-yl)Methoxy)Carbonyl)-S-Trityl-L-Cysteine-S34

Produto Controlado

CAS: 103213-32-7

Fórmula: C₃₇H₃₁NO₄₃₄S

Cor e Forma: Neat

Peso molecular: 587.61

Ref: TR-F403955

S-Trityl-N-Fomc_L-Cysteine-34S

CAS: 103213-32-7

Fórmula: SC₃₇H₃₁NO₄

Peso molecular: 587.63

Ref: 4Z-C-7722