CAS 105826-92-4

cloridrato de tropisetrona

Descrição:

cloridrato de tropisetrona é um composto químico utilizado principalmente como antiemético, particularmente na prevenção de náuseas e vômitos associados à quimioterapia e à cirurgia. Pertence à classe de antagonistas do receptor de serotonina 5-HT3, que funcionam bloqueando a ação da serotonina nesses receptores no sistema nervoso central e no trato gastrointestinal. Essa ação ajuda a mitigar as sensações de náusea e vômito. O composto é tipicamente apresentado como um pó cristalino branco a off-white, solúvel em água e metanol, o que facilita sua formulação em várias preparações farmacêuticas. Sua estrutura molecular inclui um anel de piperidina, contribuindo para sua atividade farmacológica. cloridrato de tropisetrona é administrado por via oral ou intravenosa, dependendo do cenário clínico, e geralmente é bem tolerado, embora os efeitos colaterais possam incluir dor de cabeça, constipação ou tontura. Assim como qualquer medicamento, é essencial usá-lo sob supervisão médica para garantir segurança e eficácia.

Fórmula: C₁₇H₂₀N₂O₂·ClH

InChI: InChI=1/C17H20N2O2.ClH/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16;/h2-5,10-13,18H,6-9H2,1H3;1H/t11-,12+,13+;

Chave InChI: InChIKey=XIEGSJAEZIGKSA-LUNMCBQDNA-N

SMILES: C(O[C@H]1C[C@@]2(N(C)[C@](C1)(CC2)[H])[H])(=O)C=3C=4C(NC3)=CC=CC4.Cl

Sinónimos:

• (1R,5S)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-indole-3-carboxylate hydrochloride (1:1)
• 1H-Indole-3-carboxylic acid, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrochloride (1:1)
• 1H-Indole-3-carboxylic acid, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, monohydrochloride
• 1H-Indole-3-carboxylic acid, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, monohydrochloride, endo-
• 8-methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-indole-3-carboxylate hydrochloride (1:1)
• Novaban
• Sdz-Ics 930
• Tropiserton Hydrochloride
• Tropisetron HCl
• 3-TROPANYLINDOLE-3-CARBOXYLATE HYDROCHLORIDE
• 3-Tropanylindole-3-carboxylate monohydrochloride, ICS-205,930, Navoban, 1H-Indole-3-carboxylic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester monohydrochloride
• Tropisetron monohydrochloride
• TROPISETRON HYDROCHLORIDE
• TROPISETRON HYDROCHLORIDE 98.5-101.5%
• 1H-Indole-3-carboxylic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrochloride
• (3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-INDOLE-3-CARBOXYLIC ACID ESTER MONOHYDROCHLORIDE

3-Tropanylindole-3-carboxylate hydrochloride

CAS: 105826-92-4

A selective 5-HT3 serotonin receptor antagonist

Fórmula: C₁₇H₂₀N₂O₂•HCl

Peso molecular: 320.82

Ref: 02-J62807

Tropisetron Hydrochloride

CAS: 105826-92-4

Cor e Forma: Neat

Ref: 61-FOR0763.00

TROPISETRON HYDROCHLORIDE CRS

CAS: 105826-92-4

TROPISETRON HYDROCHLORIDE CRS

Fórmula: C₁₇H₂₀N₂O₂

Cor e Forma: White. Powder.

Peso molecular: 284.3529

Ref: 41-Y0000616

(1R,3R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 1H-indole-3-carboxylate hydrochloride

CAS: 105826-92-4

Fórmula: C₁₇H₂₁ClN₂O₂

Pureza: %

Cor e Forma: Solid

Peso molecular: 320.8138

Ref: IN-DA003V99

Tropisetron hydrochloride

CAS: 105826-92-4

Tropisetron hydrochloride (Tropisetron HCl) is a selective, competitive serotonin 5-HT3 receptor antagonist, with antinauseant and antiemetic activities.

Fórmula: C₁₇H₂₁ClN₂O₂

Pureza: 99.72% - 99.83%

Cor e Forma: Solid

Peso molecular: 320.82

Ref: TM-T1173

Tropisetron hydrochloride

CAS: 105826-92-4

Fórmula: C₁₇H₂₀N₂O₂HCl

Peso molecular: 320.82

Ref: 7W-GP5100

Endo-8-Methyl-8-Azabicyclo[3.2.1]Octan-3-yl 1H-Indole-3-Carboxylate Hydrochloride

CAS: 105826-92-4

Endo-8-Methyl-8-Azabicyclo[3.2.1]Octan-3-yl 1H-Indole-3-Carboxylate Hydrochloride

Pureza: 98%

Peso molecular: 320.81g/mol

Ref: 54-OR1013106

Tropisetron hydrochloride

CAS: 105826-92-4

Tropisetron hydrochloride

Pureza: ≥98%

Peso molecular: 320.82g/mol

Ref: 54-BUP13722

Tropisetron HCl

CAS: 105826-92-4

Fórmula: C₁₇H₂₀N₂O₂·HCl

Cor e Forma: White To Off-White Solid

Peso molecular: 284.36 36.46

Ref: 4Z-T-124005

Tropisetron Hydrochloride

Produto Controlado

CAS: 105826-92-4

Fórmula: C₁₇H₂₀N₂O₂·ClH

Cor e Forma: Neat

Peso molecular: 320.81

Ref: 86-MM0763.00

Tropisetron Hydrochloride

CAS: 105826-92-4, 89565-68-4

Fórmula: C₁₇H₂₀N₂O₂·HCl

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 320.82

Ref: 3B-T2743

Tropisetron-d5

Produto Controlado

CAS: 105826-92-4

Applications Tropisetron-d5, is the labeled analogue of Tropisetron Hydrochloride (T892700), which is specific serotonin (5-HT3) receptor antagonist. It is also an antiemetic.
References Richardson, B.P., et al.: Nature, 316, 126 (1985), Williams, F.M., et al.: J. Cardiovasc. Pharmacol., 7, 550 (1985), Waeber, C., et al.: Neuroscience, 31, 393 (1989), Seynaeve, C., et al.: Anti-Cancer Drugs, 2, 343 (1991), Fischer, V., et al.: Dug Metab. Dispos., 20, 603 (1992),

Fórmula: C₁₇H₁₅D₅N₂O₂

Cor e Forma: Neat

Peso molecular: 289.38

Ref: TR-T892702

Tropisetron hydrochloride

CAS: 105826-92-4

5-HT3 receptor antagonist; alpha-7 nicotinic acetylcholine receptor partial agonist

Fórmula: C₁₇H₂₀N₂O₂•HCl

Pureza: Min. 95%

Peso molecular: 320.81 g/mol

Ref: 3D-FT28617

Tropisetron hydrochloride

CAS: 105826-92-4

Pureza: ≥98%

Peso molecular: 320.8200073

Ref: 10-F862915

Tropisetron Hydrochloride

Produto Controlado

CAS: 105826-92-4

Stability Hygroscopic
Applications Specific serotonin (5-HT3) receptor antagonist. Antiemetic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Richardson, B.P., et al.: Nature, 316, 126 (1985), Williams, F.M., et al.: J. Cardiovasc. Pharmacol., 7, 550 (1985), Waeber, C., et al.: Neuroscience, 31, 393 (1989), Seynaeve, C., et al.: Anti-Cancer Drugs, 2, 343 (1991), Fischer, V., et al.: Dug Metab. Dispos., 20, 603 (1992),

Fórmula: C₁₇H₂₀N₂O₂·ClH

Cor e Forma: White

Peso molecular: 320.81

Ref: TR-T892700

Tropisetron Hydrochloride

CAS: 105826-92-4

Fórmula: C₁₇H₂₀N₂O₂HCl

Peso molecular: 284.36 : 36.46

Ref: ST-EA-CP-T194001