CAS 10592-13-9: Doxiciclina hidroclorídrica

Descrição: Doxiciclina hidroclorídrica é um antibiótico de amplo espectro pertencente à classe das tetraciclinas, utilizado principalmente para tratar várias infecções bacterianas, incluindo infecções do trato respiratório, infecções do trato urinário e certas condições de pele. É caracterizado por sua capacidade de inibir a síntese de proteínas nas bactérias, ligando-se à subunidade ribossomal 30S, impedindo assim o crescimento e a reprodução dos microrganismos. Este composto é tipicamente administrado por via oral ou intravenosa e é conhecido por sua boa biodisponibilidade e penetração nos tecidos. Doxiciclina hidroclorídrica também é utilizado no tratamento da acne e como medida profilática contra a malária. Em termos de propriedades físicas, é um pó cristalino amarelado que é solúvel em água e exibe estabilidade sob uma variedade de condições de pH. No entanto, é sensível à luz e deve ser armazenado em um local fresco e seco para manter sua eficácia. Os efeitos colaterais podem incluir distúrbios gastrointestinais, fotossensibilidade e potenciais efeitos no desenvolvimento de ossos e dentes em crianças.

Fórmula: C₂₂H₂₄N₂O₈·ClH

InChI: InChI=1S/C22H24N2O8.ClH/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;/h4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31);1H/t7-,10+,14+,15-,17-,22-;/m0./s1

Chave InChI: InChIKey=RUYHIJHUVHIMIR-CVHRZJFOSA-N

SMILES: Cl.O=C(N)C=1C(=O)C2(O)C(O)=C3C(=O)C=4C(O)=CC=CC4C(C)C3C(O)C2C(C1O)N(C)C

Sinónimos:

• (1S,3Z,4aS,11R,11aR,12S,12aR)-3-[amino(hydroxy)methylidene]-4a,6,7,12-tetrahydroxy-N,N,11-trimethyl-2,4,5-trioxo-1,2,3,4,4a,5,11,11a,12,12a-decahydrotetracen-1-aminium chloride
• (2E,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione - ethanol (2:1) dihydrochloride hydrate
• (2Z,4S,4aR,5S,5aR,6R)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
• (2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione - ethanol (2:1) dihydrochloride hydrate
• (4S,4Ar,5S,5Ar,6R,12As)-4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,5,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-2-Naphthacenecarboxamide Hydrochloride
• (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide-ethanol hydrochloride hydrate (2:1:2:1)
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride (1:1), (4S,4aR,5S,5aR,6R,12aS)-
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aR,5S,5aR,6R,12aS)-
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, [4S-(4α,4aα,5α,5aα,6α,12aα)]-
• 2-Naphthacenecarboxamide, 4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride
• 4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,5,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-2-Na
• 4-(Dimethylamino)-3,5,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-1,4,4A,5,5A,6,11,12A-Octahydrotetracene-2-Carboxamide
• 4-(Dimethylamino)-3,5,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-1,4,4A,5,5A,6,11,12A-Octahydrotetracene-2-Carboxamide-Ethanol (2:1) Dihydrochloride Hydrate
• 6-Deoxyoxytetracycline hydrochloride
• 6-Desoxy-5-hydroxytetracycline hydrochloride
• Deoxy-5-hydroxytetracycline hydrochloride
• Deoxyoxytetracycline hydrochloride
• Doxycycline Hyclate
• Doxycycline Hyclate Monohydrate
• Doxycycline Hydrate
• Doxycycline Hydrochlocide
• Doxycycline Hydrochloride
• Doxycycline Hydrochloride Anhydrous
• Doxycycline Hydrochloride Hemiethanolate Hemihydrate
• Doxycycline hyclate COS
• Doxylin
• Farcodoxin
• Idocyklin
• Vibramycin hyclate
• Vibramycin hydrochloride
• α-6-Deoxy-5-hydroxytetracycline hydrochloride

Doxycycline Hyclate

CAS: 10592-13-924390-14-5 564-25-0

• Fórmula: C₂₂H₂₄N₂O₈C₂H₆O·HClH₂O
• Pureza: >97.0%(HPLC)
• Cor e Forma: Light yellow to Amber to Dark green powder to crystal
• Peso molecular: 512.94

Doxycycline hydrochloride, 20 mg/ml in distilled water, sterile-filtered

CAS: 10592-13-9

Doxycycline hydrochloride, is used to eliminate Borrelia burgdorferi and Anaplasma phagocytophilum in rodent reservoirs and …

• Cor e Forma: Clear pale yellow, Liquid

Doxycycline hydrochloride

CAS: 10592-13-9

Inhibits angiogenesis and reduces lung metastases by inhibiting matrix metalloproteinases.Doxycycline hydrochloride is an antibiotic used …

• Fórmula: C₂₂H₂₄N₂O₈•HCl
• Cor e Forma: Powder, Yellow
• Peso molecular: 480.9

2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride,(4S,4aR,5S,5aR,6R,12aS)-

CAS: 10592-13-9

• Fórmula: C₂₂H₂₅ClN₂O₈
• Pureza: 95%
• Cor e Forma: Solid
• Peso molecular: 480.8955

Doxycycline hydrochloride

CAS: 10592-13-9

• Fórmula: C₂₂H₂₄N₂O₈·ClH
• Cor e Forma: Powder
• Peso molecular: 480.90g/mol

Doxycycline hydrochloride

CAS: 10592-13-9

• Pureza: ≥98%
• Peso molecular: 480.9g/mol

Doxycycline HCl

CAS: 10592-13-9

• Fórmula: C₂₂H₂₄N₂O₈·HCl
• Peso molecular: 444.45 36.46

Doxycycline hydrochloride

CAS: 10592-13-9

Doxycycline hydrochloride (Hyclate) is a synthetic tetracycline derivative with similar antimicrobial activity.

• Fórmula: C₂₂H₂₄N₂O₈·HCl
• Pureza: 98.77%
• Cor e Forma: Yellow Hygroscopic Crystalline Powder
• Peso molecular: 480.9

Doxycycline hydrochloride

CAS: 10592-13-9

• Fórmula: C₂₂H₂₄N₂O₈·HCl
• Pureza: 95.0 - 102.0 % (dried basis)
• Cor e Forma: Yellow crystalline powder
• Peso molecular: 480.90

Doxycycline hydrochloride

CAS: 10592-13-9

• Pureza: 98%
• Peso molecular: 480.896

(4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride

CAS: 10592-13-9

• Pureza: 98.0%
• Cor e Forma: Solid
• Peso molecular: 480.12994344

Doxycycline HCl

CAS: 10592-13-9

Antibiotic; anti-protozoal; anti-helmintic; protein synthesis inhibitor

• Fórmula: C₂₂H₂₄N₂O₈·HCl
• Pureza: Min. 95%
• Peso molecular: 480.9 g/mol