CAS 1063331-94-1

NS13001

CAS: 1063331-94-1

NS13001, an oral SK channel modulator, shows promise for SCA2 therapy; EC50: 1.8 µM (SK2), 0.14 µM (SK3).

Fórmula: C₁₇H₁₆ClN₇

Pureza: 99.55%

Cor e Forma: Solid

Peso molecular: 353.81

Ref: TM-T16345

N-(4-Chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine

CAS: 1063331-94-1

Fórmula: C₁₇H₁₆ClN₇

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 353.8088

Ref: IN-DA0096LO

NS13001

CAS: 1063331-94-1

NS13001

Pureza: ≥98%

Peso molecular: 353.81g/mol

Ref: 54-BUP05712

N-(4-Chlorophenyl)-2-(3,5-Dimethyl-1H-Pyrazol-1-Yl)-9-Methyl-9H-Purin-6-Amine

CAS: 1063331-94-1

N-(4-Chlorophenyl)-2-(3,5-Dimethyl-1H-Pyrazol-1-Yl)-9-Methyl-9H-Purin-6-Amine

Pureza: 95%

Peso molecular: 353.81g/mol

Ref: 54-OR1025830

N-(4-Chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine

CAS: 1063331-94-1

Fórmula: C₁₇H₁₆ClN₇

Pureza: 95%

Peso molecular: 353.81

Ref: 10-F498455

N-(4-Chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine

Produto Controlado

CAS: 1063331-94-1

Fórmula: C₁₇H₁₆ClN₇

Cor e Forma: Neat

Peso molecular: 353.809

Ref: TR-N110535

NS13001

CAS: 1063331-94-1

NS13001 is a small molecule that has been shown to induce apoptotic cell death in leukemia cells. It binds to the cytochrome p450 protein, which is an important regulator of intracellular calcium. NS13001 binds to calmodulin and alters calcium signaling, leading to the activation of pro-apoptotic genes. This drug also increases the cytosolic calcium concentration by activating the ryanodine receptor, which results in cerebellar Purkinje neurons degeneration. NS13001 has been shown to be effective against lymphocytic leukemia cells that express activated caspase 3 and microglia cells.

Fórmula: C₁₇H₁₆ClN₇

Pureza: Min. 95%

Peso molecular: 353.81 g/mol

Ref: 3D-NSB33194