CAS 108050-54-0

tilmicosina

Descrição:

tilmicosina é um antibiótico macrolídeo semissintético usado principalmente na medicina veterinária, particularmente para o tratamento de infecções respiratórias em gado, como bovinos e suínos. É derivado da fermentação da bactéria *Streptomyces fradiae*. tilmicosina exibe um amplo espectro de atividade contra várias bactérias Gram-positivas e algumas bactérias Gram-negativas, tornando-o eficaz no combate a infecções causadas por patógenos como *Mycoplasma* e *Pasteurella*. O composto atua inibindo a síntese de proteínas bacterianas, impedindo assim o crescimento e a reprodução das bactérias. tilmicosina é tipicamente administrado por injeção ou em formulações de ração, e é conhecido por sua longa meia-vida, permitindo uma dosagem menos frequente. No entanto, é importante notar que tilmicosina pode ser tóxico para certas espécies animais, particularmente cavalos e humanos, levando a potenciais preocupações de segurança. Assim como com todos os antibióticos, o uso de tilmicosina deve ser gerenciado cuidadosamente para prevenir o desenvolvimento de resistência a antibióticos.

Fórmula: C₄₆H₈₀N₂O₁₃

InChI: InChI=1/C46H80N2O13/c1-13-36-33(24-57-46-44(56-12)43(55-11)40(53)31(8)59-46)19-25(2)14-15-34(49)28(5)20-32(16-17-48-22-26(3)18-27(4)23-48)42(29(6)35(50)21-37(51)60-36)61-45-41(54)38(47(9)10)39(52)30(7)58-45/h14-15,19,26-33,35-36,38-46,50,52-54H,13,16-18,20-24H2,1-12H3/b15-14+,25-19+/t26-,27+,28-,29+,30-,31-,32+,33-,35-,36-,38+,39-,40-,41-,42-,43-,44-,45+,46-/m1/s1

Chave InChI: InChIKey=JTSDBFGMPLKDCD-XVFHVFLVSA-N

SMILES: O([C@H]1[C@@H](CCN2C[C@@H](C)C[C@@H](C)C2)C[C@@H](C)C(=O)/C=C/C(/C)=C/[C@H](CO[C@H]3[C@H](OC)[C@H](OC)[C@H](O)[C@@H](C)O3)[C@@H](CC)OC(=O)C[C@@H](O)[C@@H]1C)[C@H]4[C@H](O)[C@@H](N(C)C)[C@H](O)[C@@H](C)O4

Sinónimos:

• 20-Deoxo-20-(3,5-Dimethyl-1-Piperidinyl)Desmycosin
• 4^A-O-De(2,6-dideoxy-3-C-methyl-α-<span class="text-smallcaps">L</span>-ribo-hexopyranosyl)-20-deoxo-20-[(3R,5S)-3,5-dimethyl-1-piperidinyl]tylosin
• 4A-O-De(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-20-deoxo-20-[(3R,5S)-3,5-dimethyl-1-piperidinyl]tylosin
• Antibiotic EL 870
• El 870
• Ly 177370
• Micotil
• Micotil 300
• Oxacyclohexadecane, tylosin deriv.
• Provitil
• Pulmotil
• Tilmicosin, Vetranal
• Tilmicosin  base
• Tylmicosine
• Tylosin, 4^A-O-de(2,6-dideoxy-3-C-methyl-α-<span class="text-smallcaps">L</span>-ribo-hexopyranosyl)-20-deoxo-20-[(3R,5S)-3,5-dimethyl-1-piperidinyl]-
• Tylosin, 4A-O-de(2,6-dideoxy-3-C-methyl-.alpha.-L-ribo-hexopyranosyl)-20-deoxo-20-(3R,5S)-3,5-dimethyl-1-piperidinyl-
• [(2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-{[3,6-dideoxy-3-(dimethylamino)-beta-D-glucopyranosyl]oxy}-11-{2-[(3R,5S)-3,5-dimethylpiperidin-1-yl]ethyl}-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxooxacyclohexadeca-4,6-dien-3-yl]methyl 6-deoxy-2,3-di-O-methyl-beta-D-allopyranoside
• cis-Tilmicosin
• Tylosin, 4A-O-de(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-20-deoxo-20-[(3R,5S)-3,5-dimethyl-1-piperidinyl]-
• (11Z,13Z)-6-{[4-(diMethylaMino)-3,5-dihydroxy-6-Methyloxan-2-yl]oxy}-7-[2-(3,5-diMethylpiperidin-1-yl)ethyl]-16-ethyl-4-hydroxy-15-{[(5-hydroxy-3,4-diMethoxy-6-Methyloxan-2-yl)oxy]Methyl}-5,9,13-triMethyl-1-oxacyclohexadeca-11,13-diene-2,10-dione
• 20-Deoxy-20-(3,5-diMethylpiperidin-1-yl)-desMycosin, EL-870
• 20%Tilmicosin
• Tilmicosin,20-Deoxo-20-(3,5-dimethyl-1-piperidinyl)desmycosin
• TILMICOSIN
• 4'-O-De(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-20-deoxo-20-(3,5-dimethyl-1-piperidinyl)tyrosine [antibiotic]
• Tilmicosine
• Tilmicosin (250 mg)

Tilmicosin

CAS: 108050-54-0

Antibiotics nesoi

Fórmula: C₄₆H₈₀N₂O₁₃

Cor e Forma: White Off-White Powder

Peso molecular: 868.56604

Ref: 45-1667370

Tilmicosin

CAS: 108050-54-0

Tilmicosin (EL-870), a macrolide antibiotic, treats bovine and ovine respiratory diseases in animals.

Fórmula: C₄₆H₈₀N₂O₁₃

Pureza: 97.84% - 99.5%

Cor e Forma: Solid

Peso molecular: 869.13

Ref: TM-T0777

Tilmicosin

CAS: 108050-54-0

Fórmula: C₄₆H₈₀N₂O₁₃

Pureza: ≥ 85.0% (anhydrous basis)

Cor e Forma: White to off-white powder

Peso molecular: 869.13

Ref: 7W-GP6895

Tilmicosin, 10mM (in DMSO)

CAS: 108050-54-0

Tilmicosin, 10mM (in DMSO)

Pureza: ≥95%

Peso molecular: 869.13g/mol

Ref: 54-BUP19943

Tilmicosin

CAS: 108050-54-0

Tilmicosin

Pureza: ≥98%

Peso molecular: 869.13g/mol

Ref: 54-BUP18452

Tilmicosin 100 µg/mL in Acetonitrile

CAS: 108050-54-0

Fórmula: C₄₆H₈₀N₂O₁₃

Cor e Forma: Single Solution

Peso molecular: 869.13

Ref: 04-A17582000AL-100

Tilmicosin

Produto Controlado

CAS: 108050-54-0

Fórmula: C₄₆H₈₀N₂O₁₃

Cor e Forma: Neat

Peso molecular: 869.13

Ref: 04-C17582000

Tilmicosin

CAS: 108050-54-0

Fórmula: C₄₆H₈₀N₂O₁₃

Cor e Forma: White To Off-White Solid

Peso molecular: 869.15

Ref: 4Z-T-193001

Tilmicosin, 85%

CAS: 108050-54-0

Applications Macrolide antibiotic structurally related to tylosin. Antibacterial.
References Debono, M., et al.: J. Antibiot., 42, 1253 (1989), Ose, E.E., et al.: Vet. Rec., 123, 367 (1988), Morck, D.W., et al.: J. Am. Vet. Med. Assoc., 202, 273 (1993),

Fórmula: C₄₆H₈₀N₂O₁₃

Pureza: 85%

Cor e Forma: White To Off-White

Peso molecular: 869.13

Ref: TR-T440500

Tilmicosin-d3

Produto Controlado

CAS: 108050-54-0

Applications Tilmicosin-d3 is the labeled analogue of Tilmicosin (T440500), a macrolide antibiotic structurally related to tylosin. Antibacterial.
References Debono, M., et al.: J. Antibiot., 42, 1253 (1989); Ose, E.E., et al.: Vet. Rec., 123, 367 (1988); Morck, D.W., et al.: J. Am. Vet. Med. Assoc., 202, 273 (1993)

Fórmula: C₄₆H₇₇D₃N₂O₁₃

Cor e Forma: White To Off-White

Peso molecular: 872.15

Ref: TR-T440502

Tilmicosin - Bio-X ™

CAS: 108050-54-0

Tilmicosin is a macrolide antibiotic that is used in veterinary medicine. It is used to treat bovine respiratory disease and inhibits bacterial growth by binding to the 50S ribosomal subunit of the bacteria resulting in reduced protein synthesis.

Fórmula: C₄₆H₈₀N₂O₁₃

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 869.13 g/mol

Ref: 3D-BT166387

Tilmicosin

CAS: 108050-54-0

Tilmicosin is a macrolide antibiotic with action on bacterial protein synthesis inhibition and is used for treating respiratory infections in cattle and sheep.

Fórmula: C₄₆H₈₀N₂O₁₃

Pureza: Min. 85 Area-%

Cor e Forma: White Powder

Peso molecular: 869.13 g/mol

Ref: 3D-AD31127