CAS 1082744-20-4

PF 04447943

CAS: 1082744-20-4

Fórmula: C₂₀H₂₅N₇O₂

Pureza: 98.74%

Peso molecular: 395.4582

Ref: IN-DA008TIW

PF-04447943

CAS: 1082744-20-4

PF-04447943

Pureza: ≥98%

Peso molecular: 395.46g/mol

Ref: 54-BUP12883

PF 04447943

CAS: 1082744-20-4

PF 04447943 is a small-molecule, orally bioavailable drug with potential for the treatment of inflammatory bowel disease (IBD). PF 04447943 is a potent inhibitor of TNF-α, which is involved in the pathogenesis of IBD. This compound has been shown to have statistically significant efficacy in wild-type mice and to have low expression in human nuclear DNA. The onset latency of this drug is approximately one week. PF 04447943 inhibits NF-κB and other signal pathways that are involved in the inflammatory response. It also inhibits glutamate dehydrogenase and has shown activity against natural compounds in vitro.

Fórmula: C₂₀H₂₅N₇O₂

Pureza: Min. 95%

Peso molecular: 395.46 g/mol

Ref: 3D-HTB74420

PF-04447943

CAS: 1082744-20-4

PF-04447943, a selective PDE9A inhibitor (IC50=12nM), may aid sickle cell anemia research with its anti-inflammatory properties.

Fórmula: C₂₀H₂₅N₇O₂

Pureza: 99.36% - 99.59%

Cor e Forma: Solid

Peso molecular: 395.46

Ref: TM-T16478