CAS 108321-42-2

Sulfato de geneticina

Descrição:

Sulfato de geneticina, também conhecido como G418, é um antibiótico aminoglicosídeo que é utilizado principalmente em biologia molecular para a seleção de células geneticamente modificadas. É eficaz contra uma ampla gama de bactérias e é particularmente conhecido por sua capacidade de inibir a síntese de proteínas ao se ligar à subunidade ribossômica 30S. Este composto é frequentemente utilizado em cultura celular para selecionar células que foram transfectadas com plasmídeos contendo um marcador genético para resistência ao Geneticin. A forma sulfato aumenta sua solubilidade em soluções aquosas, tornando-o adequado para aplicações laboratoriais. O Geneticin é tipicamente utilizado em concentrações que variam dependendo do tipo celular e das condições experimentais. É importante manusear Sulfato de geneticina com cuidado, pois pode ser tóxico para células não resistentes. Além disso, devido às suas propriedades antibióticas, é crucial considerar os efeitos potenciais na flora microbiana em montagens experimentais. No geral, Sulfato de geneticina é uma ferramenta valiosa na engenharia genética e na pesquisa em biologia celular.

Fórmula: C₂₀H₄₀N₄O₁₀·2H₂O₄S

InChI: InChI=1S/C20H40N4O10.H2O4S/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19;1-5(2,3)4/h6-19,24-30H,4-5,21-23H2,1-3H3;(H2,1,2,3,4)/t6-,7+,8-,9-,10-,11+,12+,13-,14-,15-,16+,17-,18-,19-,20+;/m1./s1

Chave InChI: InChIKey=QNQZPJLBGRQFDD-ZMSORURPSA-N

SMILES: O([C@@H]1[C@@H](O)[C@H](O[C@H]2O[C@]([C@@H](C)O)([C@@H](O)[C@H](O)[C@H]2N)[H])[C@@H](N)C[C@H]1N)[C@@H]3[C@H](O)[C@@H](NC)[C@@](C)(O)CO3.S(=O)(=O)(O)O

Sinónimos:

• (2R,3S,4R,5R,6S)-5-amino-6-[(1S,2R,4S,6R)-4,6-diamino-3-[(3R,4R,5R)-3,5-dihydroxy-5-methyl-4-methylamino-tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]-2-(1-hydroxyethyl)tetrahydropyran-3,4-diol
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-amino-2,7-dideoxy-<smallcap>D</smallcap>-glycero-α-<smallcap>D</smallcap>-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-<smallcap>L</span>-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2)
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-amino-2,7-dideoxy-<smallcap>D</smallcap>-glycero-α-<smallcap>D</smallcap>-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-<smallcap>L</span>-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2) (salt)
• ANTIBIOTIC G-418 Sulfate
• G-418 Sulfate
• G-418 Sulphate
• G418 Disulfate Cell Culture Tested
• G418 Disulfate Plant Cell Culture Tested
• G418 Solution
• G418 Sulfate
• Geneticin sulfate
• Sulfuric Acid
• D-Streptamine, O-2-amino-2,7-dideoxy-D-glycero-α-D-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2)

G418 disulfate, Cell Culture Reagent

CAS: 108321-42-2

G418 disulfate, cell culture reagent, 108321-42-2, is an aminoglycoside antibiotic structurally related to gentamicin B1. Learn more at Thermo Fisher Scientific.

Fórmula: C₂₀H₄₄N₄O₁₈S₂

Cor e Forma: White, Powder

Peso molecular: 692.70

Ref: 02-J62671

G418 disulfate, 50mg/ml solution

CAS: 108321-42-2

G418 disulfate, 108321-42-2, is an aminoglycoside antibiotic structurally related to gentamicin B1 suitable for cell culture. Learn more at Thermo Fisher Scientific.

Fórmula: C₂₀H₄₄N₄O₁₈S₂

Cor e Forma: Liquid, Clear colorless

Peso molecular: 692.70

Ref: 02-J63871

G 418 Disulfate Salt

CAS: 108321-42-2

Fórmula: C₂₀H₄₄N₄O₁₈S₂

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 692.7094

Ref: IN-DA00HB58

G-418 Disulphate

CAS: 108321-42-2

G-418 Disulphate

Fórmula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Pureza: 99.9%

Cor e Forma: solid

Peso molecular: 692.71g/mol

Ref: 54-BIG0175

G-418 Sulphate solution 50mg/ml

CAS: 108321-42-2

G-418 Sulphate solution 50mg/ml

Cor e Forma: Solution

Peso molecular: 594.63088g/mol

Ref: 54-BIG0176

G418 disulphate salt

CAS: 108321-42-2

Fórmula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Pureza: ≥ 720μg/mg

Cor e Forma: White to almost white powder

Peso molecular: 692.71

Ref: 7W-GA2946

G418 disulphate salt, 10% solution in water

CAS: 108321-42-2

Fórmula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Cor e Forma: Clear, colourless liquid

Peso molecular: 692.71

Ref: 7W-GP6404

G-418 disulfate

CAS: 108321-42-2

G-418 disulfate

Pureza: ≥98%

Peso molecular: 692.71g/mol

Ref: 54-BUP18758

G-418.Sulfate Solid

CAS: 108321-42-2

M01801 - G-418.Sulfate Solid

Fórmula: C₂₀H₄₄N₄O₁₈S₂

Pureza: >90.0%(HPLC)(N)

Cor e Forma: Solid

Peso molecular: 692.7

Ref: 10-M01801

Geneticin Disulfate

CAS: 108321-42-2

Fórmula: C₂₀H₄₀N₄O₁₀·2H₂O₄S

Peso molecular: 496.56 2*98.07

Ref: 4Z-G-215001

G-418 disulfate

CAS: 108321-42-2

G-418 disulfate (Geneticin sulfate) is an aminoglycoside antibiotic, which blocks polypeptide synthesis by inhibiting the elongation step in cells.

Fórmula: C₂₀H₄₀N₄O₁₀·2H₂O₄S

Pureza: 98% - 99.9%

Cor e Forma: White To Off-White Powder

Peso molecular: 692.71

Ref: TM-T6512

Geneticin sulfate

CAS: 108321-42-2

Geneticin is very efficient against gram-negative bacteria, however it is not applied for treating infections due to high renal toxicity. Geneticin and its resistance genes found application in the selection of transgenic cell lines including yeasts such as P. pastoris and S. serevisiae, other eukaryotic cell lines such as CHO or HEK293, but also plant cells and bacterial cells.

Fórmula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Pureza: Min. 98 Area-%

Cor e Forma: White Powder

Peso molecular: 692.71 g/mol

Ref: 3D-AG11347

G418 Disulfate

CAS: 108321-42-2, 49863-47-0

Fórmula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Pureza: >90.0%(HPLC)(N)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 692.70

Ref: 3B-G0349

G-418 Sulphate (Geneticin) for tissue culture

CAS: 108321-42-2

Fórmula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Cor e Forma: White to off-white, Crystalline powder, Clear to slightly hazy, Colourless to pale yellow

Peso molecular: 692.70

Ref: SR-87858

G-418 Sulphate (Geneticin) extrapure

CAS: 108321-42-2

Fórmula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Cor e Forma: White to off-white, Crystalline powder, Clear to slightly hazy, Colourless to pale yellow

Peso molecular: 692.70

Ref: SR-58327

G-418.Sulfate, Sterile-Filtered Solution

CAS: 108321-42-2

M01802 - G-418.Sulfate, Sterile-Filtered Solution

Fórmula: C₂₀H₄₄N₄O₁₈S₂

Pureza: >90.0%(HPLC)(N)

Cor e Forma: Liquid

Peso molecular: 692.7

Ref: 10-M01802

Geneticin Disulfate Salt

CAS: 108321-42-2

Fórmula: C₂₀H₄₀N₄O₁₀·2H₂O₄S

Cor e Forma: White To Off-White

Peso molecular: 692.71

Ref: TR-G360580

Geneticin Disulfate (G418), Antibiotic for Culture Media Use Only

CAS: 108321-42-2

Geneticin is very efficient against gram-negative bacteria, however it is not applied for treating infections due to high renal toxicity. Geneticin and its resistance genes found application in the selection of transgenic cell lines including yeasts such as P. pastoris and S. serevisiae, other eukaryotic cell lines such as CHO or HEK293, but also plant cells and bacterial cells.

Fórmula: C₂₀H₄₄N₄O₁₈S₂

Pureza: Min. 97.0 Area-%

Peso molecular: 692.71 g/mol

Ref: 3D-G-2400

Geneticin Disulfate Salt

CAS: 108321-42-2

Fórmula: C₂₀H₄₀N₄O₁₀(H₂SO₄)

Peso molecular: 496.56 : 2(98.07)

Ref: ST-EA-CP-G33036