CAS 108930-17-2

H 7 di-hidrocloreto

Descrição:

H7 di-hidrocloreto, com o número CAS 108930-17-2, é um composto químico que tipicamente exibe características associadas à sua estrutura molecular e grupos funcionais. Como um sal di-hidrocloreto, é provável que seja um sólido cristalino estável à temperatura ambiente, solúvel em água e outros solventes polares devido à presença de íons cloreto. O composto pode exibir propriedades básicas, uma vez que é derivado de uma base que foi protonada por ácido clorídrico. Suas interações moleculares podem incluir ligações de hidrogênio, o que pode influenciar sua solubilidade e reatividade. H7 di-hidrocloreto pode ser utilizado em várias aplicações, incluindo formulações farmacêuticas, onde pode servir como um ingrediente ativo ou um agente estabilizante. As fichas de dados de segurança normalmente indicariam precauções de manuseio, como acontece com muitas substâncias químicas, para mitigar os riscos associados à exposição. No geral, as características específicas do H7 di-hidrocloreto dependeriam de sua estrutura molecular precisa e do contexto de seu uso.

Fórmula: C₁₄H₁₇N₃O₂S·2ClH

InChI: InChI=1S/C14H17N3O2S.2ClH/c1-11-9-16-7-8-17(11)20(18,19)14-4-2-3-12-10-15-6-5-13(12)14;;/h2-6,10-11,16H,7-9H2,1H3;2*1H

Chave InChI: InChIKey=OARGPFMFRLLKPF-UHFFFAOYSA-N

SMILES: S(=O)(=O)(C=1C2=C(C=CC1)C=NC=C2)N3C(C)CNCC3.Cl

Sinónimos:

• (+/-)-1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine 2Hcl
• (+/-)-1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine Dihydrochloride
• (+/-)-1-(5-Isoquinolinesulphonyl)-2-Methylpiperazine Dihydrochloride
• (-)-1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine, Di-Hcl Salt
• (3R)-4-(isoquinolin-5-ylsulfonyl)-3-methylpiperazin-1-ium
• (3S)-4-(isoquinolin-5-ylsulfonyl)-3-methylpiperazin-1-ium
• 1-(5-Isoquinolinylsulfonyl)-2-Methyl-Piperazine Dihydrochloride
• 5-[(2-Methylpiperazin-1-Yl)Sulfonyl]Isoquinoline Dihydrochloride
• 5-[(2-Methylpiperazin-1-Yl)Sulfonyl]Isoquinoline Hydrochloride
• H-7
• Isoquinoline, 5-[(2-methyl-1-piperazinyl)sulfonyl]-, hydrochloride (1:2)
• Piperazine, 1-(5-isoquinolinylsulfonyl)-2-methyl-, dihydrochloride

H-7 dihydrochloride

CAS: 108930-17-2

Protein kinase inhibitor. Inhibits cyclic nucleotide dependent protein kinase (PKA) and protein kinase C This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa A

Fórmula: C₁₄H₁₇N₃O₂S•2HCl

Peso molecular: 364.29

Ref: 02-J61697

Protein kinase inhibitor H-7 2HCl

CAS: 108930-17-2

Fórmula: C₁₄H₁₉Cl₂N₃O₂S

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 364.2906

Ref: IN-DA007TT5

Protein kinase inhibitor H-7 dihydrochloride

CAS: 108930-17-2

Protein kinase inhibitor H-7 dihydrochloride

Pureza: ≥98%

Peso molecular: 364.29g/mol

Ref: 54-BUP06296

H-7 dihydrochloride

CAS: 108930-17-2

Fórmula: C₁₄H₁₇N₃O₂S₂HCl

Peso molecular: 364.29

Ref: 7W-GK5980

Protein kinase inhibitor H-7 dihydrochloride

CAS: 108930-17-2

Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor.

Fórmula: C₁₄H₁₉Cl₂N₃O₂S

Pureza: 99.54%

Cor e Forma: White Crystalline Solid

Peso molecular: 364.29

Ref: TM-T22831

1-(5-Isoquinolinesulfonyl)-2-methylpiperazine Dihydrochloride

Produto Controlado

CAS: 108930-17-2

Applications A selective inhibitor of protein kinase C or cyclic-nucleotide-dependent protein kinases.
References Hidaka, H. and Kawamoto, S.: Biochem. and Biophys. Res. Comm., 125, 1, 258 (1984)

Fórmula: C₁₄H₁₇N₃O₂S·2ClH

Cor e Forma: Neat

Peso molecular: 364.29

Ref: TR-I885000

H-7 dihydrochloride

CAS: 108930-17-2

H-7 is a cytostatic agent that inhibits the activation of transcription by inhibiting the synthesis of DNA and RNA. H-7 has shown to be an effective inhibitor of epidermal growth factor and α subunit, which are involved in the proliferation of cancer cells. In addition, H-7 can inhibit calcium ion influx into the cell, which may cause cell death. This drug also has potent inducers effects on primary cells, such as HL-60 cells, and induces apoptosis in carcinoma cell lines. H-7 is not an inhibitor of cyclase activity but enhances it when added with guanine nucleotide binding proteins (G proteins) activators such as forskolin. This leads to increased levels of cyclic AMP. As a result, H-7 inhibits protein synthesis and activates cytosolic calcium channels.

Fórmula: C₁₄H₁₇N₃O₂S·2HCl

Pureza: Min. 95%

Peso molecular: 364.29 g/mol

Ref: 3D-IEA93017