CAS 109358-47-6

N-[(1,1-Dimetiletoxicarbonil)-L-leucil-L-lisil-N-(4-metil-2-oxo-2H-1-benzopiran-7-il)-L-argininamida

Descrição:

N-[(1,1-Dimetiletoxicarbonil)-L-leucil-L-lisil-N-(4-metil-2-oxo-2H-1-benzopiran-7-il)-L-argininamida, com número CAS 109358-47-6, é um composto sintético caracterizado por sua estrutura complexa, que inclui múltiplos resíduos de aminoácidos e um moiety de benzopirano. Este composto apresenta um grupo protetor de dimetiletoxicarbonilo, que é comumente usado na síntese de peptídeos para proteger o grupo amino dos aminoácidos. A presença de L-leucina, L-lisina e L-arginina indica que é um derivado de peptídeo, potencialmente exibindo atividade biológica. O componente de benzopirano sugere propriedades farmacológicas potenciais, uma vez que compostos dessa classe estão frequentemente associados a efeitos antioxidantes e anti-inflamatórios. A estrutura molecular geral implica que pode interagir com sistemas biológicos, possivelmente influenciando a síntese de proteínas ou a atividade enzimática. Sua solubilidade, estabilidade e reatividade dependeriam das condições específicas, como pH e solvente, tornando-o um candidato para mais pesquisas em química medicinal e desenvolvimento de medicamentos.

Fórmula: C₃₃H₅₂N₈O₇

InChI: InChI=1S/C33H52N8O7/c1-19(2)16-25(41-32(46)48-33(4,5)6)30(45)40-23(10-7-8-14-34)29(44)39-24(11-9-15-37-31(35)36)28(43)38-21-12-13-22-20(3)17-27(42)47-26(22)18-21/h12-13,17-19,23-25H,7-11,14-16,34H2,1-6H3,(H,38,43)(H,39,44)(H,40,45)(H,41,46)(H4,35,36,37)/t23-,24-,25-/m0/s1

Chave InChI: InChIKey=RRHPIUJOSIJECH-SDHOMARFSA-N

SMILES: CC=1C=2C(=CC(NC([C@@H](NC([C@@H](NC([C@@H](NC(OC(C)(C)C)=O)CC(C)C)=O)CCCCN)=O)CCCNC(=N)N)=O)=CC2)OC(=O)C1

Sinónimos:

• <span class="text-smallcaps">L</smallcap>-Argininamide, N-[(1,1-dimethylethoxy)carbonyl]-<smallcap>L</smallcap>-leucyl-<smallcap>L</span>-lysyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
• Boc-Leu-Lys-Arg-AMC
• Boc-Leu-Lys-Arg-Amc Hydrochloride Salt
• N-[(1,1-Dimethylethoxy)carbonyl]-<span class="text-smallcaps">L</smallcap>-leucyl-<smallcap>L</smallcap>-lysyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-<smallcap>L</span>-argininamide
• L-Argininamide, N-[(1,1-dimethylethoxy)carbonyl]-L-leucyl-L-lysyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
• N-[(1,1-Dimethylethoxy)carbonyl]-L-leucyl-L-lysyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-argininamide

Boc-Leu-Lys-Arg-AMC

CAS: 109358-47-6

Boc-LKR-AMC, a good substrate for the Kex2 endoprotease (kexin, previously known as proteinase yscF), a membrane-bound, calcium-dependent serine protease from yeast α-cells.

Fórmula: C₃₃H₅₂N₈O₇

Pureza: 98.4%

Cor e Forma: White Crystalline Powder

Peso molecular: 672.83

Ref: 01-4017091

Boc-Leu-Lys-Arg-AMC

CAS: 109358-47-6

Boc-Leu-Lys-Arg-AMC is an inhibitor of the human erythrocyte receptor for thrombin. It has shown activity in a number of other protein interactions, such as with the human receptor for epidermal growth factor (EGF) and the human receptor for insulin-like growth factor II. Boc-Leu-Lys-Arg-AMC is used as a research tool to study the function of proteins, including ion channels and receptors. This compound is also used as an antibody in immunological studies that examine protein interactions. Boc-Leu-Lys-Arg-AMC can be purchased in high purity and at a reasonable price from our store.

Fórmula: C₃₃H₅₂N₈O₇

Pureza: Min. 95%

Peso molecular: 672.82 g/mol

Ref: 3D-MLK-3141-V

Boc-Leu-Lys-Arg-AMC hydrochloride salt

CAS: 109358-47-6

Boc-Leu-Lys-Arg-AMC is a synthetic substrate that has been used in a number of clinical studies to identify the serine proteases that are involved in autoimmune diseases. It is a synthetic peptide composed of the amino acid sequence found in soybean trypsin. The peptide was shown to have high salt tolerance and was able to be hydrolyzed by polyclonal antibodies with specificity for amyloid protein, suggesting it may be useful as a biochemical marker for Alzheimer's disease. Boc-Leu-Lys-Arg-AMC has also been shown to be an efficient substrate for collagenase, which is an enzyme that breaks down collagen and causes tissue damage. This property makes this compound useful as a proteolytic agent for the removal of unwanted scar tissue or other lesions from diseased organs. Boc-Leu-Lys-Arg-AMC also has an optimum pH level of 7.5 and is active against influenza

Fórmula: C₃₃H₅₂N₈O₇

Pureza: Min. 95%

Peso molecular: 672.82 g/mol

Ref: 3D-FB110554