CAS 1093978-89-2

2H-1-Benzazepin-2-ona,6-fluoro-1,3,4,5-tetrahidro-3-[4-[3-metoxi-4-(4-metil-1H-imidazol-1-il)fenil]-1H-1,2,3-triazol-1-il]-1-(2,2,2-trifluoroetil)-

Descrição:

2H-1-Benzazepina-2-ona, 6-fluoro-1,3,4,5-tetrahidro-3-[4-[3-metoxi-4-(4-metil-1H-imidazol-1-il)fenil]-1H-1,2,3-triazol-1-il]-1-(2,2,2-trifluoroetil)-, identificado pelo número CAS 1093978-89-2, é um composto orgânico complexo caracterizado por sua estrutura multicíclica, que inclui um núcleo de benzazepina fundido com um moiety de triazol e imidazol. A presença de um átomo de flúor e um grupo trifluoroetil sugere aplicações potenciais em química medicinal, particularmente no desenvolvimento de fármacos com atividade biológica ou seletividade aprimoradas. Os substituintes metoxi e metila podem influenciar a solubilidade e lipofilicidade do composto, afetando suas propriedades farmacocinéticas. Além disso, a disposição intrincada dos grupos funcionais indica potencial para diversas interações com alvos biológicos, tornando-o um candidato para investigação adicional na descoberta de fármacos. No geral, este composto exemplifica a complexidade frequentemente encontrada na química orgânica sintética moderna, particularmente no contexto do design de moléculas para uso terapêutico.

Fórmula: C₂₅H₂₂F₄N₆O₂

Sinónimos:

• 6-fluoro-3-[4-[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]triazol-1-yl]-1-(2,2,2-trifluoroethyl)-4,5-dihydro-3H-1-benzazepin-2-one
• 2H-1-benzazepin-2-one, 6-fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl]-1-(2,2,2-trifluoroethyl)-
• 2H-1-Benzazepin-2-one 6-fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl]-1-(2,2,2-trifluoroethyl)-
• 6-Fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl]-1-(2,2,2-trifluoroethyl)-2H-1-Benzazepin-2-one
• gaMMa-secretase Modulator 2
• 6-fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl]-1-(2,2,2-trifluoroethyl)-2H-1-Benzazepin-2-on
• Merck gamma-secretase modulator
• gamma secretase modulator 2,gammasecretase modulator 2
• 6-Fluoro-1,3,4,5-tetrahydro-3-[4-[3-Methoxy-4-(4-Methyl-1H-iMidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-
• Merck γ-secretase Modulator

6-Fluoro-1,3,4 ,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1 ,2,3-triazol-1-yl]-1-(2-trifluoroethyl)-2H-1-benzazepin-2-one

CAS: 1093978-89-2

6-Fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-- 1,2,3-triazol-1yl]-1-(2trifluoroethyl)-2H-1benzazepin-2one (6FTH) is an anticancer drug that belongs to the class of benzothiazole derivatives. It has been shown to have potent antiangiogenic and antiproliferative properties in preclinical studies. 6FTH has been shown to be effective against colon cancer and breast cancer cells in vitro. It also inhibits the growth of squamous cell carcinoma cells by downregulating the expression of proteins involved in tumorigenesis. The compound has been found to be safe when used as an adjuvant to a combination therapy containing cisplatin

Fórmula: C₂₅H₂₂F₄N₆O₂

Pureza: Min. 98 Area-%

Cor e Forma: Powder

Peso molecular: 514.48 g/mol

Ref: 3D-FB151723

6-Fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl]-1-(2,2,2-trifluoroethyl)-2H-1-benzazepin-2-one

Produto Controlado

CAS: 1093978-89-2

Fórmula: C₂₅H₂₂F₄N₆O₂

Cor e Forma: Neat

Peso molecular: 514.475

Ref: TR-F257310

γ-secretase modulator 2

CAS: 1093978-89-2

Gamma-secretase modulator 2 selectively targets Alzheimer's by reducing Aβ(1-42), aiding in prevention and treatment.

Fórmula: C₂₅H₂₂F₄N₆O₂

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 514.47

Ref: TM-T11359