CAS 1094873-17-2

(R)-JNJ-31020028

CAS: 1094873-17-2

(R)-JNJ-31020028: High-affinity, selective brain-penetrant Y2 receptor antagonist; pIC50: human 8.07, rat 8.22, mouse 8.21.

Fórmula: C₃₄H₃₆FN₅O₂

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 565.68

Ref: TM-T12623

JNJ 31020028

CAS: 1094873-17-2

JNJ 31020028 is a research tool used in cell biology and pharmacology. It has been shown to bind to the activator protein-1 (AP-1) transcription factor, which regulates proinflammatory cytokines, such as tumor necrosis factor-alpha (TNF-α). JNJ 31020028 inhibits AP-1 activity by binding to the double zinc finger motif of the DNA binding domain and blocking its interaction with DNA. This agent also binds to the TGFβ receptor and blocks TGFβ signaling.

Fórmula: C₃₄H₃₆FN₅O₂

Pureza: Min. 95%

Peso molecular: 565.7 g/mol

Ref: 3D-UTB87317