CAS 109806-71-5

2-[4-[(4-clorofenil)-fenilmetil]piperazin-1-il]etanol

Descrição:

2-[4-[(4-clorofenil)-fenilmetil]piperazin-1-il]etanol, com o número CAS 109806-71-5, é um composto químico que pertence à classe de derivados de piperazina. Esta substância apresenta um anel de piperazina, que é um anel de seis membros contendo dois átomos de nitrogênio, e é substituído por um grupo fenilmetila e um grupo 4-clorofenila. A presença do grupo hidroxila (-OH) na parte de etanol da molécula contribui para sua potencial solubilidade em solventes polares. Este composto é frequentemente estudado por suas propriedades farmacológicas, particularmente no contexto da neurofarmacologia, uma vez que os derivados de piperazina são conhecidos por exibirem várias atividades biológicas, incluindo efeitos antipsicóticos e ansiolíticos. A substituição clorofenílica pode influenciar sua interação com alvos biológicos, potencialmente aumentando sua eficácia ou alterando seu perfil farmacocinético. No geral, as características estruturais deste composto sugerem que ele pode ter implicações significativas na química medicinal e no desenvolvimento de medicamentos.

Fórmula: C₁₉H₂₅Cl₃N₂O

InChI: InChI=1S/C19H23ClN2O/c20-18-8-6-17(7-9-18)19(16-4-2-1-3-5-16)22-12-10-21(11-13-22)14-15-23/h1-9,19,23H,10-15H2

Chave InChI: InChIKey=ZJQSBXXYLQGZBR-UHFFFAOYSA-N

SMILES: C(N1CCN(CCO)CC1)(C2=CC=C(Cl)C=C2)C3=CC=CC=C3

Sinónimos:

• 1-Piperazineethanol, 4-(p-chloro-α-phenylbenzyl)-
• 1-Piperazineethanol, 4-[(4-chlorophenyl)phenylmethyl]-
• 2-[4-{4-Chlorophenyl} Phenylmethyl]-1-Piperazinylethanol
• 2-{4-[(4-CHLORO-PHENYL)-PHENYL-METHYL]-piperazin-1-YL}-ETHANOL
• 2-{4-[(4-Chlorophenyl)(phenyl)methyl]-1-piperazinyl}ethanol
• 4-[(4-Chlorophenyl)phenylmethyl]-1-piperazine
• 4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol
• Cetirizine ethanol
• Cetirizine impurity G
• Unii-Pgv947X9B1
• 2-[4-[(4-Chlorophenyl)phenylmethyl]piperazin-1-yl]ethanol
• Cetirizine Impurity 15 Monomer （Cetirizine EP Impurity G Monomer ）
• 4-[(4-Chlorophenyl)phenylMethyl]-(4-hydroxy-1-piperidinyl)-1-butanone
• 2-[4-{Chlorophenyl}Phenylmethyl]-1-
• Levocetirizine Impurity G
• 4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol
• Cetirizine -EP-Imp-G
• Levocetirizine Impurity 6
• Cetirizine EP Impurity G Hydrochloride

Cetirizine EP Impurity G (Cetirizine USP Related Compound G (Free Form), Levocetirizine EP Impurity H)

CAS: 109806-71-5

Fórmula: C₁₉H₂₃ClN₂O

Cor e Forma: Pale Yellow Semi-Solid (Low M P )

Peso molecular: 330.86

Ref: 4Z-C-2012

4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol

CAS: 109806-71-5

Stability Very Hygroscopic
Applications 4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol is used in the synthesis of antifungal triazole and imidazole derivatives. Impurity of an intermediate in the formation of Cetrizine.
References Rezaei, Z. et al.: Archiv. Pharm., 344, 658 (2011)

Fórmula: C₁₉H₂₃ClN₂O

Cor e Forma: White To Off-White

Peso molecular: 330.85

Ref: TR-C377565

2-[4-[(4-CHLOROPHENYL)-PHENYLMETHYL]PIPERAZIN-1-YL]ETHANOL

CAS: 109806-71-5

Fórmula: C₁₉H₂₅Cl₃N₂O

Pureza: 95.0%

Peso molecular: 403.77

Ref: 10-F540017

4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol-d4

Produto Controlado

CAS: 109806-71-5

Fórmula: C₁₉H₁₉D₄ClN₂O

Cor e Forma: Neat

Peso molecular: 334.88

Ref: TR-C377567

4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride

CAS: 109806-71-5

4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride is a cholinergic drug that is used to treat allergic rhinitis in children and adults. It has been shown to be well tolerated in pediatric patients and geriatric patients, as well as being an innovative, labile, and biopharmaceutical compound. 4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride is not metabolized by the liver and does not have significant side effects. It has a low potential for abuse because of its low solubility in water. It is an antihistamine that blocks the action of histamine at H1 receptors on smooth muscle cells in the nose, which helps reduce nasal congestion and sneezing.

Fórmula: C₁₉H₂₃ClN₂O·2HCl

Pureza: Min. 95%

Peso molecular: 403.77 g/mol

Ref: 3D-FC53582