CAS 109838-85-9

(R)-2,5-dihidro-3,6-dimetoxi-2-isopropilpirazina

Descrição:

(R)-2,5-dihidro-3,6-dimetoxi-2-isopropilpirazina é um composto químico caracterizado por sua estrutura única de anel de pirazina, que contribui para suas propriedades aromáticas. Este composto apresenta dois grupos metóxi (-OCH3) nas posições 3 e 6, aumentando sua solubilidade e reatividade. A presença de um grupo isopropílico na posição 2 adiciona ao seu volume estérico, influenciando suas interações e aplicações potenciais. Como uma molécula quiral, ela existe em duas formas enantioméricas, sendo a configuração (R) de particular interesse em vários campos, incluindo a química de sabores e fragrâncias, devido aos seus atributos sensoriais distintos. O composto é tipicamente sintetizado através de reações orgânicas específicas que permitem a introdução seletiva de grupos funcionais. Suas aplicações podem se estender à indústria alimentícia, onde pode ser utilizado como agente aromatizante, bem como no desenvolvimento de fragrâncias. No geral, (R)-2,5-dihidro-3,6-dimetoxi-2-isopropilpirazina é notável por suas características estruturais e potencial utilidade em várias aplicações químicas.

Fórmula: C₉H₁₆N₂O₂

InChI: InChI=1/C9H16N2O2/c1-6(2)8-9(13-4)10-5-7(11-8)12-3/h6,8H,5H2,1-4H3/t8-/m1/s1

SMILES: CC(C)[C@@H]1C(=NCC(=N1)OC)OC

Sinónimos:

• (R)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine
• (R)-2-Isopropyl-3,6-dimethoxy-2,5-dihydropyrazine
• (2R)-3,6-dimethoxy-2-(propan-2-yl)-2,5-dihydropyrazine
• (2R)-2,5-Dihydro-2-isopropyl-3,6-dimethoxypyrazine
• 2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine
• (2R)-(-)-2,5-DIHYDRO-3,6-DIMETHOXY-2-ISOPROPYLPYRAZINE
• (2R)-2,5-Dihydro-3,6-dimethoxy-2-(1-methylethyl)pyrazine
• BISLACTIMETHER
• (2R)-(-)-2,5-DIHYDRO-3,6-DIMETHOXY-2-ISOPROPYLPYRAZINE, 98+%
• (2R)-3,6-DIMETHOXY-2-(1-METHYLETHYL)-2,5-DIHYDROPYRAZINE
• (R)-2,5-DIMETHOXY-3-ISOPROPYL-3,6-DIHYDROPYRAZINE
• zR{-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine
• SCHOELLKOPF-HARTWIG-REAGENT
• (2R)-(-)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine (aka (R )-Schollkopf reagent)
• (R)-2,5-DIHYDRO-3,6-DIMETHOXY-2-ISOPROPYLPIPERAZINE
• (-)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine
• (R)-Schollkopf Reagent
• Pyrazine, 2,5-dihydro-3,6-dimethoxy-2-(1-methylethyl)-, (2R)-(9CI)

(R)-3-Isopropyl-2,5-dimethoxy-3,6-dihydropyrazine, 98%

CAS: 109838-85-9

(R)-3-Isopropyl-2,5-dimethoxy-3,6-dihydropyrazineChiral auxiliary for the synthesis of -amino acids. It is an inhibitor with antitumor activity. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer

Fórmula: C₉H₁₆N₂O₂

Pureza: 98%

Cor e Forma: Colorless to yellow to orang, Liquid

Peso molecular: 184.24

Ref: 02-H56077

(R)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine

CAS: 109838-85-9

Fórmula: C₉H₁₆N₂O₂

Pureza: 96%

Cor e Forma: Liquid

Peso molecular: 184.2355

Ref: IN-DA0032ER

(R)-3-Isopropyl-2,5-dimethoxy-3,6-dihydropyrazine

CAS: 109838-85-9

(R)-3-Isopropyl-2,5-dimethoxy-3,6-dihydropyrazine

Fórmula: C₉H₁₆N₂O₂

Pureza: 99%

Cor e Forma: colourless to light yellow liquid

Peso molecular: 184.24g/mol

Ref: 54-OR925455

(R)-2-Isopropyl-3,6-dimethoxy-2,5-dihydropyrazine

CAS: 109838-85-9

Fórmula: C₉H₁₆N₂O₂

Pureza: >95.0%(GC)

Cor e Forma: Colorless to Yellow clear liquid

Peso molecular: 184.24

Ref: 3B-D3256

(R)-2-Isopropyl-3,6-dimethoxy-2,5-dihydropyrazine

CAS: 109838-85-9

Pureza: 98%

Peso molecular: 184.238998413086

Ref: 10-F790908

(R)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine

CAS: 109838-85-9

(R)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine and its enantiomer (S)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine are also known as Schöllkopf chiral auxiliaries or Schöllkopf reagents, and are used to produce optically pure α-amino acids via asymmetric synthesis. The Schöllkopf reagent can be deprotonated at the prochiral α-carbon, and the resulting enolate is trapped with electrophiles to yield adducts with high (typically > 95% d.e.) diastereoselectivity. The enolate is essentially planar, and the steric bulk of the isopropyl group directs the incoming electrophile to attack from the opposite face, yielding trans adducts. A wide range of electrophiles including alkyl halides, alkyl sulfonates, acyl chlorides, aldehydes, ketones, epoxides, thioketones and enones can be used. Hydrolysis, typically under mild acidic conditions, yields the non-substituted amino acid with high (typically > 95 e.e.) enantiopurity.

Fórmula: C₉H₁₆N₂O₂

Pureza: Min. 98%

Cor e Forma: Colorless Yellow Clear Liquid

Peso molecular: 184.24 g/mol

Ref: 3D-FD04039

(R)-2-Isopropyl-3,6-dimethoxy-2,5-dihydropyrazine (>85% Purity)

Produto Controlado

CAS: 109838-85-9

Stability Moisture Sensitive
Applications An inhibitor with antitumor activity.
References Plumb, J., et al.: Mol. Cancer Ther., 2, 721 (2003), de Ruijter, A., et al.: Biochem. J., 370, 737 (2003), Dey, P., et al.: Curr. Med. Chem., 13, 2909 (2006), Maiso, P., et al.: Cancer Res., 66, 5781 (2006), Paris, M., et al.: J. Med. Chem., 51, 1505 (2008),

Fórmula: C₉H₁₆N₂O₂

Pureza: >85%

Cor e Forma: Neat

Peso molecular: 184.24

Ref: TR-I824430