CAS 11021-13-9

ginsenosídeo rb2

Descrição:

ginsenosídeo rb2 é um glicosídeo natural e um dos principais componentes ativos encontrados no ginseng, particularmente no ginseng Panax. Pertence à classe de compostos conhecidos como saponinas, que se caracterizam por sua natureza anfipática, permitindo que interajam com ambientes hidrofílicos e hidrofóbicos. ginsenosídeo rb2 é conhecido por suas potenciais propriedades farmacológicas, incluindo efeitos anti-inflamatórios, antioxidantes e neuroprotetores. Acredita-se que modula várias vias biológicas, contribuindo para seu potencial terapêutico em condições como estresse, fadiga e declínio cognitivo. O composto geralmente apresenta baixa toxicidade e é frequentemente estudado por seu papel na melhoria da função imunológica e na promoção da saúde geral. Sua solubilidade em água é limitada, o que pode afetar sua biodisponibilidade, tornando as estratégias de formulação importantes para seu uso eficaz em suplementos dietéticos e medicamentos à base de plantas. No geral, ginsenosídeo rb2 é um composto significativo na medicina tradicional, com pesquisas em andamento explorando seus mecanismos de ação e potenciais benefícios à saúde.

Fórmula: C₅₃H₉₀O₂₂

InChI: InChI=1/C53H90O22/c1-23(2)10-9-14-53(8,75-47-43(67)39(63)37(61)29(72-47)22-69-45-41(65)34(58)26(57)21-68-45)24-11-16-52(7)33(24)25(56)18-31-50(5)15-13-32(49(3,4)30(50)12-17-51(31,52)6)73-48-44(40(64)36(60)28(20-55)71-48)74-46-42(66)38(62)35(59)27(19-54)70-46/h10,24-48,54-67H,9,11-22H2,1-8H3/t24-,25+,26-,27+,28+,29+,30-,31+,32-,33-,34-,35+,36+,37+,38-,39?,40-,41+,42+,43+,44+,45-,46-,47-,48-,50-,51+,52+,53-/m0/s1

Chave InChI: InChIKey=NODILNFGTFIURN-GZPRDHCNSA-N

SMILES: C[C@]12[C@@]3(C)[C@@]([C@@]([C@@](O[C@@H]4O[C@H](CO[C@H]5[C@H](O)[C@@H](O)[C@@H](O)CO5)[C@@H](O)[C@H](O)[C@H]4O)(CCC=C(C)C)C)(CC3)[H])([C@H](O)C[C@@]1([C@]6(C)[C@@](CC2)(C(C)(C)[C@@H](O[C@H]7[C@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@@H](CO)O7)CC6)[H])[H])[H]

Sinónimos:

• (3beta,12beta)-12-hydroxy-20-[(6-O-pentopyranosylhexopyranosyl)oxy]dammar-24-en-3-yl 2-O-hexopyranosylhexopyranoside
• (3beta,12beta)-20-{[(3xi)-6-O-(alpha-L-arabinopyranosyl)-beta-D-ribo-hexopyranosyl]oxy}-12-hydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
• (3β,12β)-20-[(6-O-α-<span class="text-smallcaps">L</smallcap>-Arabinopyranosyl-β-<smallcap>D</smallcap>-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 2-O-β-<smallcap>D</smallcap>-glucopyranosyl-β-<smallcap>D</span>-glucopyranoside
• 12-hydroxy-20-[(6-O-pentopyranosylhexopyranosyl)oxy]dammar-24-en-3-yl 2-O-hexopyranosylhexopyranoside
• 20-((6-O-alpha-L-Arabinopyranosyl-beta-D-glucopyranosyl)oxy)-12beta-hydroxydammar-24-en-3beta-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
• Dammarane, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• Ginsenoside C
• Ginsenoside Rb₂
• Nsc 308878
• beta-D-Glucopyranoside, (3-beta,12-beta)-20-((6-O-alpha-L-arabinopyranosyl-beta-D-glucopyranosyl)oxy)-12-hydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl-
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,12β)-20-[(6-O-α-<smallcap>L</smallcap>-arabinopyranosyl-β-<smallcap>D</smallcap>-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 2-O-β-<smallcap>D</span>-glucopyranosyl-
• Ginsenoside Rb2
• (3β,12β)-20-[(6-O-α-L-Arabinopyranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside
• Dammarane, β-D-glucopyranoside deriv.
• β-D-Glucopyranoside, (3β,12β)-20-[(6-O-α-L-arabinopyranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-
• beta-d-glucopyranoside,(3-beta,12-beta)-20-((6-o-alpha-l-arabinopyranosyl-beta
• ginsenosidec
• -d-glucopyranosyl)oxy)-12-hydroxydammar-24-en-3-yl2-o-beta-d-glucopyranosyl-
• arabinopyranosyl-β-D-glucopyranosyl)oxy]-12-
• β-D-Glucopyranoside,(3β,12β)-20-[(6-O-α-L-
• GINSENOSIDE RB2 WITH HPLC

Ginsenoside Rb2

CAS: 11021-13-9

Ginsenoside Rb2 analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fórmula: C₅₃H₉₀O₂₂

Pureza: (HPLC) ≥97%

Cor e Forma: Powder

Peso molecular: 1079.29

Ref: 11-0104S

Ginsenoside Rb2

CAS: 11021-13-9

Fórmula: C₅₃H₉₀O₂₂

Cor e Forma: White To Off-White Solid

Peso molecular: 1079.28

Ref: 4Z-G-157011

Ginsenoside Rb2

CAS: 11021-13-9

Fórmula: C₅₃H₉₀O₂₂

Peso molecular: 1079.27

Ref: 7W-GC5019

Ginsenoside Rb2

CAS: 11021-13-9

Ginsenosides, which are active compounds found in ginseng (Panax ginseng), are used as antidiabetic treatments; ginsenoside Rb2 may inhibit palmitate-induced gluconeogenesis via AMPK-induced SHP by relieving ER stress, a cause of gluconeogenesis.

Fórmula: C₅₃H₉₀O₂₂

Pureza: 95%~99%

Cor e Forma: White powder

Peso molecular: 1079.28

Ref: BP-BP0658

Ginsenoside Rb2

CAS: 11021-13-9

Ginsenoside Rb2 (Ginsenoside C) found in species of Panax, upregulating GPR120 gene expression.

Fórmula: C₅₃H₉₀O₂₂

Pureza: 99.01% - 99.93%

Cor e Forma: White Powder

Peso molecular: 1079.27

Ref: TM-T3919

Ginsenoside rb2

CAS: 11021-13-9

Natural glycoside

Fórmula: C₅₃H₉₀O₂₂

Pureza: ≥ 90.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 1079.29

Ref: 5G-89209

Ginsenoside Rb2

Produto Controlado

CAS: 11021-13-9

Applications Ginsenoside Rb2 inhibits the catecholamines secretory responses activated by nicotinic stimulation and by direct membrane depolarization from isolated perfused rat adrenal medulla.
References Lim, H., et. al.: Korean J. Physiol. Pha., 18, 431 (2014)

Fórmula: C₅₃H₉₀O₂₂

Cor e Forma: Neat

Peso molecular: 1079.27

Ref: TR-G387605

Ginsenoside Rb2

CAS: 11021-13-9

Ginsenoside Rb2 is a bioactive compound, which is a type of ginsenoside found predominantly in Panax ginseng. It is sourced from the root of the ginseng plant, where it functions as one of the major active constituents contributing to the plant's medicinal properties. The mode of action of Ginsenoside Rb2 involves modulation of multiple signaling pathways, including antioxidant, anti-inflammatory, and anti-cancer pathways. It influences cellular metabolism, apoptosis, and immune responses, thereby playing a critical role in the therapeutic effects of ginseng.

Fórmula: C₅₃H₉₀O₂₂

Pureza: Min. 98 Area-%

Cor e Forma: Powder

Peso molecular: 1,079.3 g/mol

Ref: 3D-OG09287

Ginsenoside Rb2

CAS: 11021-13-9

Fórmula: C₅₃H₉₀O₂₂

Peso molecular: 1079.3

Ref: ST-EA-CP-G62002