CAS 110429-35-1

Cloridrato de paroxetina hemihidrato

Descrição:

Cloridrato de paroxetina hemihidrato é um inibidor seletivo da recaptação de serotonina (ISRS) utilizado principalmente no tratamento do transtorno depressivo maior, transtornos de ansiedade e transtorno obsessivo-compulsivo. É caracterizado por sua fórmula química, que inclui uma forma de sal de cloridrato e um hemidrato, indicando a presença de moléculas de água em sua estrutura cristalina. Este composto geralmente aparece como um pó branco a off-white e é solúvel em água, o que facilita sua absorção no corpo. A paroxetina atua inibindo a recaptação de serotonina no cérebro, aumentando assim os níveis de serotonina e melhorando o humor. A forma hemidratada sugere que contém meia molécula de água para cada molécula de cloridrato de paroxetina, o que pode influenciar sua estabilidade e solubilidade. Assim como muitos fármacos, é essencial manusear Cloridrato de paroxetina hemihidrato com cuidado, seguindo as diretrizes de segurança para evitar possíveis efeitos colaterais e interações com outros medicamentos.

Fórmula: C₁₉H₁₇ClD₄FNO₃

InChI: InChI=1/C19H20FNO3.ClH/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18;/h1-6,9,14,17,21H,7-8,10-12H2;1H/t14?,17-;/m0./s1

Chave InChI: InChIKey=QRQSGFFISBKLMZ-YHOFXEKLSA-N

SMILES: C(OC=1C=C2C(=CC1)OCO2)[C@H]3[C@@H](CCNC3)C4=CC=C(F)C=C4.Cl.O

Sinónimos:

• (-)-trans-4-(4-Fluorophenyl)-3-(3,4-methylenedioxyphenoxymethyl)piperidine hydrochloride hemihydrate
• (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine hydrochloride (1:1)
• (3s-trans)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine hydrochloride Hemihydrate
• (4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine hydrochloride (1:1)
• Paroxetine-D4 Hcl
• Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, hydrochloride, hydrate (2:1), (3S,4R)-
• Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, hydrochloride, hydrate (2:1), (3S-trans)-
• Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, hydrochloride, hydrate (2:2:1), (3S,4R)-
• paroxetine hydrochloride Hemihydrate
• Paroxetine HCl,Hemihydrate
• PAROXETINE HYDROCHLORIDE HEMIHYDRATE: (+/-)- TRANS-PAROXETINE HYDROCHLORIDE
• (3S-trans)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine hydrochloride
• 3-(Benzo[1,3]dioxol-5-yloxymethyl)-4-(4-fluoro-phenyl)-piperidine
• Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, hydrochloride, hydrate (2:1), (3S,4R)- (9CI)
• (-)-(3S,4R)-Paroxetine hydrochloride hemihydrate
• BRL29060A hemihydrate
• Paroxetine hydrochloride salt hemihydrate
• aroxetine hydrochloride hemihydrate
• (3S,4R)-(-)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine Hydrochloride
• 1,3-benzodioxol-5-yl-[4-(4-fluorophenyl)-3-piperidinyl]methanol hydrochloride
• BRL29060 hydrochloride hemihydrate
• ParoxetineHydrochlorideHemihydrate&gt
• PAROXETINE-D4 HCL USP/EP/BP
• PAROXETINE HEMIHYDRATE, EP/BP/USP
• Paroxetine Hydrochloride (350 mg)G0D0030.972mg/mg(ai)
• PAROXETINE HYDROCHLORIDE 1/2H2O
• Paroxetine hydrochloride
• Paroxetine hydrochloride hemihydrate, 99%, selective serotonin-reuptake inhibitors (SSRIs)
• PAROXETINE-D4 HCL kf-yuwen(at)kf-chem.com
• paroxetine hydrochloride hydrate
• Paroxetine Hydrochloride (350 mg)
• Paroxetine hydrochloride hemihydrate, >=99%

Paroxetine Hydrochloride Hemihydrate

CAS: 110429-35-1, 61869-08-7, 78246-49-8

Fórmula: C₁₉H₂₀FNO₃·HClH₂O

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 374.84

Ref: 3B-P1977

Paroxetine.HCl.hemihydrate, 1mg/ml in Methanol (as free base)

CAS: 110429-35-1

Cor e Forma: Single Solution

Ref: LP-PRX-1254-HC-1LM

Paroxetine.HCl.hemihydrate

CAS: 110429-35-1

Cor e Forma: Neat

Ref: LP-PRX-1254-HC-10

Paroxetine Hydrochloride Hemihydrate 1.0 mg/ml in Methanol (as anhydrous free base)

CAS: 110429-35-1

Cor e Forma: Single Solution

Ref: 61-AMP0264.00-01

Paroxetine Hydrochloride Hemihydrate

CAS: 110429-35-1

Cor e Forma: Neat

Ref: 61-FOR0264.00

Paroxetine impurity standard

CAS: 110429-35-1, 533-31-3

Paroxetine impurity standard

Cor e Forma: White

Ref: 47-746

Paroxetine hydrochloride hemihydrate

CAS: 110429-35-1

Paroxetine hydrochloride hemihydrate

Fórmula: C₁₉H₂₀FNO₃HCl

Pureza: 97.4%

Cor e Forma: Off-White

Peso molecular: 365.1194

Ref: 47-1024

PAROXETINE HYDROCHLORIDE HEMIHYDRATE CRS

CAS: 110429-35-1

PAROXETINE HYDROCHLORIDE HEMIHYDRATE CRS

Fórmula: C₃₈H₄₄Cl₂F₂N₂O₇

Cor e Forma: Crystalline Powder. White. Powder.

Peso molecular: 749.668

Ref: 41-Y0000281

PAROXETINE FOR SYSTEM SUITABILITY CRS

CAS: 110429-35-1

PAROXETINE FOR SYSTEM SUITABILITY CRS

Ref: 41-Y0000630

Paroxetine Hydrochloride

CAS: 110429-35-1

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Fórmula: C₁₉H₂₀FNO₃·HClH₂O

Cor e Forma: White Off-White Crystalline Powder

Peso molecular: 329.14272

Ref: 45-1500218

Paroxetine Hydrochloride Hemihydrate

CAS: 110429-35-1

Paroxetine Hydrochloride Hemihydrate

Pureza: 98%

Peso molecular: 374.83g/mol

Ref: 54-PC109214

Paroxetine hydrochloride hemihydrate

CAS: 110429-35-1

Paroxetine hydrochloride hemihydrate

Pureza: ≥98%

Peso molecular: 749.67g/mol

Ref: 54-BUP13721

Paroxetine HCl

CAS: 110429-35-1

Fórmula: C₁₉H₂₀FNO₃·HCl

Cor e Forma: White To Off-White Solid

Peso molecular: 329.37 36.46

Ref: 4Z-P-021

Paroxetine hydrochloride

CAS: 110429-35-1

Fórmula: C₁₉H₂₀FNO₃·HCl·5(H₂O)

Pureza: 98.0 - 102.0 % (anhydrous basis)

Cor e Forma: White crystalline powder

Peso molecular: 374.83

Ref: 7W-GP8602

Paroxetine Hydrochloride Hemihydrate

CAS: 110429-35-1

Cor e Forma: Neat

Ref: 86-MM0264.00

Paroxetine Hydrochloride RS

CAS: 110429-35-1

Cor e Forma: White Solid Crystalline Powder

Ref: 2K-1114500021

Paroxetine Hydrochloride Hemihydrate

CAS: 110429-35-1

Fórmula: C₁₉H₂₀FNO₃HCl(H₂O)

Peso molecular: 329.4 : 36.46 : 1/2(18.0)

Ref: ST-EA-CP-P217000

Paroxetine HCl (hemihydrate)

Produto Controlado

CAS: 110429-35-1

A serotonin reuptake inhibitor with anticholinergic activity and mild inhibitory activity on noradrenaline reuptake. Paroxetine has been used for the treatment of depression, anxiety disorders, post-traumatic stress disorder, premenstrual dysphoric disorder and obsessive-compulsive disorder.  Also inhibits nitric oxide synthase and cytochrome isoenzyme P450 2D6.

Fórmula: C₁₉H₂₀FNO₃•HCl•(H₂O)₀

Pureza: Min. 98 Area-%

Cor e Forma: White Powder

Peso molecular: 374.83 g/mol

Ref: 3D-FP60426

Paroxetine HCl hemihydrate - Bio-X ™

Produto Controlado

CAS: 110429-35-1

Paroxetine belongs to a class of drugs called selective serotonin reuptake inhibitors. It is used as an antidepressant and anxiolytic agent but also for post-traumatic stress disorder, premenstrual dysphoric disorder and obsessive-compulsive disorder. Paroxetine inhibits the activity of the enzyme, which is responsible for the re-uptake of serotonin in nerve cells and thus increases its concentration in the synaptic space. Additionally, it inhibits nitric oxide synthase and cytochrome isoenzyme P450 2D6.

Fórmula: C₁₉H₂₀FNO₃·HClH₂O

Pureza: Min. 98 Area-%

Cor e Forma: Powder

Peso molecular: 374.83 g/mol

Ref: 3D-BP164263

USP Paroxetine Related Compound E Mixture

Produto Controlado

CAS: 1012886-75-7, 110429-35-1

Applications USP Paroxetine Related Compound E Mixture is a reference standard composed of Paroxetine Hydrochloride (P205750) spiked with 4-(4-Fluorophenyl)-1,2,3,6-tetrahydro-1-methyl-pyridine Hydrochloride (F595220). Paroxetine Hydrochloride (P205750) is a selective serotonin reuptake inhibitor. Used as an antidepressant. 4-(4-Fluorophenyl)-1,2,3,6-tetrahydro-1-methyl-pyridine Hydrochloride (F595220) is the active metabolite of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) (M325910), N-Methyl-4-phenylpyridinium (MPP+), selectively destroys the dopaminergic neurons and induces the symptoms of Parkinson's disease.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lassen, J.B.: Eur. J. Pharmacol., 47, 351 (1978), Lund, J., et al.: Acta Pharmacol. Toxicol., 51, 351, (1982); Gerlach, M., et al.: Eur. J. Pharmacol., 208, 273 (1991), Tipton, K., et al.: J. Neurochem., 61, 1191 (1993), Wimalasena, D., et al.: J. Biol. Chem., 279, 15298 (2004),

Fórmula: C₁₉H₂₀FNO₃·C₁₂H₁₄FN·HCl

Cor e Forma: Neat

Peso molecular: 557.07

Ref: TR-P205790