CAS 11051-90-4

(3β,11α,12β,14β)-11-(Acetiloxi)-3-[(O-6-desoxi-3-O-metil-β-D-alopiranosil-(1→4)-O-2,6-didesoxi-3-O-metil-β-D-arabino-hexopiranosil-(1→4)-2,6-didesoxi-3-O-metil-β-D-ribo-hexopiranosil)oxi]-14-hidroxi-12-[(1-oxo-3-fenil-2-propen-1-il)oxi]pregnan-20-ona

Descrição:

A substância química com o nome "(3β,11α,12β,14β)-11-(Acetiloxi)-3-[(O-6-desoxi-3-O-metil-β-D-alopiranosil-(1→4)-O-2,6-didesoxi-3-O-metil-β-D-arabino-hexopiranosil-(1→4)-2,6-didesoxi-3-O-metil-β-D-ribo-hexopiranosil)oxi]-14-hidroxi-12-[(1-oxo-3-fenil-2-propen-1-il)oxi]pregnan-20-ona" é uma molécula orgânica complexa caracterizada por sua estrutura esteroide, que é típica dos pregnanos. Este composto apresenta múltiplos grupos funcionais, incluindo acetoxi, hidroxilo e ligações glicosídicas, indicando sua potencial atividade biológica e interação com vários sistemas biológicos. A presença de unidades de açúcar sugere que pode exibir propriedades relacionadas à glicosilação, o que pode influenciar a solubilidade, estabilidade e bioatividade. O grupo fenila ligado à molécula sugere possíveis interações aromáticas, que podem desempenhar um papel em seus efeitos farmacológicos. No geral, a estrutura intrincada deste composto sugere que pode ter implicações significativas na química medicinal, particularmente no desenvolvimento de agentes terapêuticos. Seu número CAS, 11051-90-4, permite uma identificação precisa em bancos de dados químicos e literatura.

Fórmula: C₅₃H₇₈O₁₇

InChI: InChI=1S/C53H78O17/c1-27(54)35-21-23-53(59)36-18-17-33-24-34(20-22-51(33,6)42(36)47(66-31(5)55)49(52(35,53)7)68-39(56)19-16-32-14-12-11-13-15-32)67-40-25-37(60-8)45(29(3)63-40)69-41-26-38(61-9)46(30(4)64-41)70-50-44(58)48(62-10)43(57)28(2)65-50/h11-16,19,28-30,33-38,40-50,57-59H,17-18,20-26H2,1-10H3

Chave InChI: InChIKey=ZKWQLHAAXWFVPF-UHFFFAOYSA-N

SMILES: O(C(C)=O)C1C2C(C3(O)C(C)(C1OC(C=CC4=CC=CC=C4)=O)C(C(C)=O)CC3)CCC5C2(C)CCC(OC6CC(OC)C(OC7CC(OC)C(OC8C(O)C(OC)C(O)C(C)O8)C(C)O7)C(C)O6)C5

Sinónimos:

• (3β,11α,12β,14β)-11-(Acetyloxy)-3-[(O-6-deoxy-3-O-methyl-β-<span class="text-smallcaps">D</smallcap>-allopyranosyl-(1→4)-O-2,6-dideoxy-3-O-methyl-β-<smallcap>D</smallcap>-arabino-hexopyranosyl-(1→4)-2,6-dideoxy-3-O-methyl-β-<smallcap>D</span>-ribo-hexopyranosyl)oxy]-14-hydroxy-12-[(1-oxo-3-phenyl-2-propen-1-yl)oxy]pregnan-20-one
• (3β,8xi,9xi,11α,12β,14β)-11-(acetyloxy)-3-{[6-deoxy-3-O-methyl-β-D-allopyranosyl-(1->4)-2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl]oxy}-14-hydroxy-20-oxopregnan-12-yl (2E)-3-phenylprop-2-enoate
• Condurango glycoside A
• Pregnan-20-one, 11-(acetyloxy)-3-[(O-6-deoxy-3-O-methyl-β-<span class="text-smallcaps">D</smallcap>-allopyranosyl-(1→4)-O-2,6-dideoxy-3-O-methyl-β-<smallcap>D</smallcap>-arabino-hexopyranosyl-(1→4)-2,6-dideoxy-3-O-methyl-β-<smallcap>D</span>-ribo-hexopyranosyl)oxy]-14-hydroxy-12-[(1-oxo-3-phenyl-2-propen-1-yl)oxy]-, (3β,11α,12β,14β)-
• Pregnan-20-one, 11-(acetyloxy)-3-[(O-6-deoxy-3-O-methyl-β-<span class="text-smallcaps">D</smallcap>-allopyranosyl-(1→4)-O-2,6-dideoxy-3-O-methyl-β-<smallcap>D</smallcap>-arabino-hexopyranosyl-(1→4)-2,6-dideoxy-3-O-methyl-β-<smallcap>D</span>-ribo-hexopyranosyl)oxy]-14-hydroxy-12-[(1-oxo-3-phenyl-2-propenyl)oxy]-, (3β,11α,12β,14β)-
• (3β,11α,12β,14β)-11-(Acetyloxy)-3-[(O-6-deoxy-3-O-methyl-β-D-allopyranosyl-(1→4)-O-2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl-(1→4)-2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl)oxy]-14-hydroxy-12-[(1-oxo-3-phenyl-2-propen-1-yl)oxy]pregnan-20-one
• Pregnan-20-one, 11-(acetyloxy)-3-[(O-6-deoxy-3-O-methyl-β-D-allopyranosyl-(1→4)-O-2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl-(1→4)-2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl)oxy]-14-hydroxy-12-[(1-oxo-3-phenyl-2-propen-1-yl)oxy]-, (3β,11α,12β,14β)-
• Pregnan-20-one, 11-(acetyloxy)-3-[(O-6-deoxy-3-O-methyl-β-D-allopyranosyl-(1→4)-O-2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl-(1→4)-2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl)oxy]-14-hydroxy-12-[(1-oxo-3-phenyl-2-propenyl)oxy]-, (3β,11α,12β,14β)-

Condurango glycoside A

CAS: 11051-90-4

Condurango glycoside A activates p53, induces ROS generation, up-regulates p53 expression, and triggers apoptosis as well as premature senescence associated

Fórmula: C₅₃H₇₈O₁₇

Cor e Forma: Solid

Peso molecular: 987.18

Ref: TM-T79991

Condurango glycoside a

CAS: 11051-90-4

Natural glycoside

Fórmula: C₅₃H₇₈O₁₇

Pureza: ≥ 90.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 987.18

Ref: 5G-83941

Condurangoglykosid A

CAS: 11051-90-4

Condurangoglykosid A is a natural product and an anticancer drug that has shown to be effective in the treatment of prostate cancer. This drug inhibits the growth of tumour cells by preventing necrosis factor from binding to the cell membrane, which prevents the release of cytochrome C from mitochondria. Condurangoglykosid A also protects liver cells from damage and death by inhibiting toxins that are released into the body during cancer treatment. Condurangoglykosid A also inhibits tumor growth by blocking nuclear factor kappa-light-chain-enhancer (NFκB) activation in cancer cells. This drug can be administered orally and has been shown to be safe for human use. It has been observed that Condurangoglykosid A may have an antitumor effect on cervical cancer cells, but this has not been confirmed yet.

Fórmula: C₅₃H₇₈O₁₇

Pureza: Min. 95%

Peso molecular: 987.2 g/mol

Ref: 3D-LAA05190