CAS 11061-68-0
:insulina humana
Descrição:
insulina humana, com o número CAS 11061-68-0, é um hormônio peptídico produzido pelo pâncreas que desempenha um papel crucial no metabolismo da glicose. É composto por 51 aminoácidos e tem um peso molecular de aproximadamente 5.800 daltons. A insulina funciona principalmente para reduzir os níveis de glicose no sangue, facilitando a captação de glicose nas células, particularmente no tecido muscular e adiposo, e inibindo a produção hepática de glicose. A estrutura da insulina consiste em duas cadeias, A e B, ligadas por ligações dissulfeto, que são essenciais para sua atividade biológica. A insulina é tipicamente administrada por injeção devido à sua natureza proteica, pois não é eficaz quando tomada por via oral devido à degradação no trato gastrointestinal. É utilizada terapeuticamente no manejo do diabetes mellitus, ajudando a controlar os níveis de açúcar no sangue em indivíduos com deficiência ou resistência à insulina. insulina humana é produzido através da tecnologia de DNA recombinante, garantindo um suprimento consistente e seguro para uso médico.
Fórmula:C257H383N65O77S6
InChI:InChI=1/C257H383N65O77S6/c1-29-131(23)205(313-193(339)104-259)252(393)317-204(130(21)22)248(389)288-159(75-82-200(349)350)217(358)282-156(71-78-189(263)335)221(362)308-183-116-403-404-117-184-243(384)305-178(111-324)240(381)294-162(88-123(7)8)225(366)295-168(95-140-53-61-146(329)62-54-140)228(369)283-154(69-76-187(261)333)218(359)290-161(87-122(5)6)223(364)285-158(74-81-199(347)348)220(361)302-174(101-190(264)336)235(376)298-170(97-142-57-65-148(331)66-58-142)231(372)309-182(242(383)304-176(255(396)397)103-192(266)338)115-402-401-114-181(214(355)273-107-194(340)278-153(72-79-197(343)344)216(357)281-151(51-42-84-271-257(267)268)212(353)272-108-195(341)279-166(93-138-46-36-32-37-47-138)227(368)297-167(94-139-48-38-33-39-49-139)230(371)299-171(98-143-59-67-149(332)68-60-143)238(379)320-208(135(27)327)254(395)322-85-43-52-186(322)246(387)286-152(50-40-41-83-258)222(363)321-209(136(28)328)256(398)399)311-250(391)203(129(19)20)316-236(377)164(90-125(11)12)292-229(370)169(96-141-55-63-147(330)64-56-141)296-224(365)160(86-121(3)4)289-210(351)133(25)277-215(356)157(73-80-198(345)346)287-247(388)202(128(17)18)315-237(378)165(91-126(13)14)293-233(374)173(100-145-106-270-120-276-145)301-239(380)177(110-323)280-196(342)109-274-213(354)180(113-400-405-118-185(310-244(183)385)245(386)319-207(134(26)326)253(394)306-179(112-325)241(382)318-206(132(24)30-2)251(392)312-184)307-226(367)163(89-124(9)10)291-232(373)172(99-144-105-269-119-275-144)300-219(360)155(70-77-188(262)334)284-234(375)175(102-191(265)337)303-249(390)201(127(15)16)314-211(352)150(260)92-137-44-34-31-35-45-137/h31-39,44-49,53-68,105-106,119-136,150-186,201-209,323-332H,29-30,40-43,50-52,69-104,107-118,258-260H2,1-28H3,(H2,261,333)(H2,262,334)(H2,263,335)(H2,264,336)(H2,265,337)(H2,266,338)(H,269,275)(H,270,276)(H,272,353)(H,273,355)(H,274,354)(H,277,356)(H,278,340)(H,279,341)(H,280,342)(H,281,357)(H,282,358)(H,283,369)(H,284,375)(H,285,364)(H,286,387)(H,287,388)(H,288,389)(H,289,351)(H,290,359)(H,291,373)(H,292,370)(H,293,374)(H,294,381)(H,295,366)(H,296,365)(H,297,368)(H,298,376)(H,299,371)(H,300,360)(H,301,380)(H,302,361)(H,303,390)(H,304,383)(H,305,384)(H,306,394)(H,307,367)(H,308,362)(H,309,372)(H,310,385)(H,311,391)(H,312,392)(H,313,339)(H,314,352)(H,315,378)(H,316,377)(H,317,393)(H,318,382)(H,319,386)(H,320,379)(H,321,363)(H,343,344)(H,345,346)(H,347,348)(H,349,350)(H,396,397)(H,398,399)(H4,267,268,271)/t131-,132-,133-,134?,135?,136?,150-,151-,152-,153-,154-,155-,156-,157-,158-,159-,160-,161-,162-,163-,164-,165-,166-,167-,168-,169-,170-,171-,172-,173-,174-,175-,176-,177-,178-,179-,180-,181-,182-,183-,184-,185-,186-,201-,202-,203-,204-,205-,206-,207-,208-,209-/m0/s1
Sinónimos:- Insulin, Zinc, Human, Recomb.
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14 produtos.
Insulin solution (4mg/mL) [Optimized for Cell Culture]
CAS:Cor e Forma:Colorless to Almost colorlessclear liquidInsulin Human
CAS:Insulin and its saltsFórmula:C257H383N65O77S6Cor e Forma:White Lyophilized CakePeso molecular:5803.63765High Molecular Weight Insulin Human
CAS:Insulin and its saltsFórmula:C257H383N65O77S6(monomer)Cor e Forma:White Off-White PowderPeso molecular:5803.63765Insulin Human, recombinant
CAS:Fórmula:C257H383N65O77S6Pureza:95.0 - 105.0 % (dried basis)Cor e Forma:White to off-white powderPeso molecular:5807.57Insulin (human)
CAS:Insulin (human) is a peptide hormone that promotes glycogen synthesis and regulates glucose levels in the blood.Fórmula:C257H383N65O77S6Pureza:97.32% - 99.99%Cor e Forma:SolidPeso molecular:5807.57Insulin (Human)
CAS:<p>Applications Insulin (Human) is a peptide hormone regulating the metabolism of carbohydrates and fats. It is used in the treatment of those suffering from the diabetes type I and II metabolic disorders. Regulates the absorption of glucose from the blood to skeletal muscles and fat storage.<br>References Lai, Y. et al.: Biochem. J., 460, 363 (2014); Hedman, C. et al.: Clin. Endocrinol., 81, 58 (2014);<br></p>Fórmula:C257H383N65O77S6Cor e Forma:NeatPeso molecular:5807.57Insulin (Human)
CAS:<p>Insulin is a peptide hormone that regulates the uptake and storage of glucose by muscle and fat cells. Insulin is produced by beta cells in the pancreas, which release it into the bloodstream when blood sugar levels rise. Insulin lowers glucose levels by increasing the amount of glucose taken up from the blood into muscle and fat cells, suppressing hepatic gluconeogenesis, and promoting glycolysis. It also increases protein synthesis, decreases proteolysis, and stimulates growth. With a molecular weight of 5808 Da, insulin is composed of two polypeptide chains with an approximate molecular weight of 3120 Da each linked by disulfide bonds. Insulin has no lipid moiety or carbohydrate moiety.<br>Insulin binds to its receptor on the surface of a cell to trigger one or more signaling cascades leading to changes in metabolism. Binding to the receptor triggers a conformational change in the receptor that causes insulin to be released from its binding site on the receptor.</p>Fórmula:C257H383N65O77S6Pureza:Min. 95%Peso molecular:5,807.6 g/molInsulin
CAS:Insulin is a hormone that is produced by beta cells in the pancreas and regulates blood sugar levels. It is used for the treatment of diabetes mellitus, a disease in which the body does not produce enough insulin or cannot use insulin properly. Insulin works by lowering the level of glucose (sugar) in the blood, thereby regulating its supply to various parts of the body. Insulin has been shown to be effective at reducing postprandial blood glucose concentrations. This drug also lowers blood glucose concentrations by stimulating glucose uptake into muscle and adipose tissue. Insulin is also used to treat type 1 diabetes, gestational diabetes, and other conditions where low insulin production results in high blood sugar levels.Fórmula:C257H383N65O77S6Pureza:Reported (%)Cor e Forma:PowderPeso molecular:5,807.57 g/molInsulin (Human)
CAS:<p>Human insulin is a peptide hormone produced by beta cells in the pancreas. The insulin receptor is found on the surface of liver, fat, and muscle cells. When binding to its receptor, insulin opens ion channels allowing potassium ions to flow into the cell and sodium ions to flow out of the cell. This change in ion concentration causes an electrical potential across the membrane that triggers an influx of calcium ions from outside the cell. These changes result in an increase in glucose uptake by tissues and inhibition of glucose production by the liver. Insulin also binds to a secondary receptor called IGF-1R (insulin-like growth factor) which activates intracellular signaling pathways involving PI3K and Akt kinase. Insulin can be used as a research tool for studying protein-protein interactions or as a pharmacological agent for diabetes treatment. <br>This product is enzymatically derived from Porcine Insulin A-chain, available as a 0.5mg vial and contains disulfide bonds between CysA6-CysA11,CysA7-CysB7, and CysA20-CysB19.</p>Fórmula:C257H383N65O77S6Pureza:Min. 95%Peso molecular:5,807.6 g/molr-Insulin ex. Human for cell culture, 25 USP U/mg, Endotoxin (BET) 1.0EU/mg
CAS:Fórmula:C257H383N65O77S6Cor e Forma:White, PowderPeso molecular:~ 5808Insulin Human (COLD SHIPMENT REQUIRED) (DISCONTINUED)
CAS:Insulin and its saltsFórmula:C257H383N65O77S6Cor e Forma:White CrystalsPeso molecular:5803.63765Ref: IN-DA008RHX
Produto descontinuado
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