CAS 11079-53-1

Hiperforina

Descrição:

Hiperforina é um composto polifenólico que ocorre naturalmente, encontrado principalmente na planta Hypericum perforatum, comumente conhecida como erva de São João. É reconhecido por seu papel como um constituinte bioativo, contribuindo para as propriedades medicinais da planta, particularmente no tratamento da depressão leve a moderada. Hiperforina exibe uma estrutura complexa, caracterizada por um sistema bicíclico fundido e múltiplos grupos funcionais, que contribuem para seus efeitos farmacológicos. Sabe-se que atua como um inibidor seletivo da recaptação de serotonina e norepinefrina, aumentando os níveis de neurotransmissores no cérebro. Além disso, Hiperforina possui propriedades anti-inflamatórias e antimicrobianas, tornando-o de interesse em várias aplicações terapêuticas. O composto é lipofílico, o que influencia sua absorção e biodisponibilidade no corpo. A estabilidade de Hiperforina pode ser afetada por fatores como luz e pH, exigindo manuseio e armazenamento cuidadosos. No geral, Hiperforina é um composto significativo na medicina herbal, com pesquisas em andamento explorando seu pleno potencial e mecanismos de ação.

Fórmula: C₃₅H₅₂O₄

InChI: InChI=1/C35H52O4/c1-22(2)13-12-19-33(11)27(16-14-23(3)4)21-34(20-18-25(7)8)30(37)28(17-15-24(5)6)31(38)35(33,32(34)39)29(36)26(9)10/h13-15,18,26-27,37H,12,16-17,19-21H2,1-11H3/t27-,33+,34+,35-/m0/s1

Chave InChI: InChIKey=IWBJJCOKGLUQIZ-HQKKAZOISA-N

SMILES: C(C(C)C)(=O)[C@@]12[C@@](CCC=C(C)C)(C)[C@@H](CC=C(C)C)C[C@@](CC=C(C)C)(C1=O)C(=O)C(CC=C(C)C)=C2O

Sinónimos:

• (1R,5R,7S,8R)-1-butanoyl-4-hydroxy-8-methyl-3,5,7-tris(3-methylbut-2-en-1-yl)-8-(4-methylpent-3-en-1-yl)bicyclo[3.3.1]non-3-ene-2,9-dione
• (1R,5R,7S,8R)-4-hydroxy-8-methyl-3,5,7-tris(3-methylbut-2-en-1-yl)-8-(4-methylpent-3-en-1-yl)-1-(2-methylpropanoyl)bicyclo[3.3.1]non-3-ene-2,9-dione
• (1R,5S,6R,7S)-4-Hydroxy-6-methyl-1,3,7-tris(3-methyl-2-buten-1-yl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-penten-1-yl)bicyclo[3.3.1]non-3-ene-2,9-dione
• 4-Hydroxy-6-methyl-1,3,7-tris(3-methyl-2-butenyl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-pentenyl) bicyclo(3.3.1)non-3-ene-2,9-dione
• Bicyclo(3.3.1)(1,4)benzodiazepin-5-one, 4-Hydroxy-6-methyl-1,3,7-tris(3-methyl-2-butenyl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-pentenyl)-, (1R,5S,6R,7S)-
• Bicyclo[3.3.1]non-3-ene-2,9-dione, 4-hydroxy-6-methyl-1,3,7-tris(3-methyl-2-buten-1-yl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-penten-1-yl)-, (1R,5S,6R,7S)-
• Bicyclo[3.3.1]non-3-ene-2,9-dione, 4-hydroxy-6-methyl-1,3,7-tris(3-methyl-2-butenyl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-pentenyl)-, (1R,5S,6R,7S)-
• Bicyclo[3.3.1]non-3-ene-2,9-dione, 4-hydroxy-6-methyl-1,3,7-tris(3-methyl-2-butenyl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-pentenyl)-, [1R-(6-endo,7-exo)]-
• Bicyclo[3.3.1]non-3-ene-2,9-dione, 4-hydroxy-6-methyl-1,3,7-tris(3-methyl-2-butenyl)-S-(2-methyl-1-oxopropyl)-6-(4-methyl-3-pentenyl)-, [1R-(1α,5α,6β,7α)]-
• Hsdb 7646
• Hyperforin
• Hyperforin (solution in Ethanol)
• (1R,5S)-4-Hydroxy-6-methyl-1,3,7β-tris(3-methyl-2-butenyl)-5-(2-methyl-1-oxopropyl)-6α-(4-methyl-3-pentenyl)bicyclo[3.3.1]non-3-ene-2,9-dione
• Bicyclo[3.3.1]non-3-ene-2,9-dione, 4-hydroxy-6-
• HYPERFORIN MIX(P)
• HYPERFORIN USP/EP/BP
• methyl-1,3,7-tris(3-methyl-2-buten-1-yl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-penten-1-yl)-,(1R,5S,6R,7S)-

Hyperforin

CAS: 11079-53-1

Hyperforin

Pureza: ≥95%

Peso molecular: 536.79g/mol

Ref: 54-BUP22066

Hyperforin

CAS: 11079-53-1

Fórmula: C₃₅H₅₂O₄

Peso molecular: 536.78

Ref: 7W-GK2499

Hyperforin

CAS: 11079-53-1

Hyperforin, a natural product from Hypericum, is antidepress, inflammatory, antitumor and antiangiogenic effects, acts as a MRI and activates TRPC6 channels.

Fórmula: C₃₅H₅₂O₄

Pureza: 98%

Cor e Forma: White To Off-White Powder

Peso molecular: 536.79

Ref: TM-TN1755

Hyperforin

CAS: 11079-53-1

Fórmula: C₃₅H₅₂O₄

Pureza: 95%~99%

Peso molecular: 536.797

Ref: BP-BP0751

Hyperforin

CAS: 11079-53-1

Fórmula: C₃₅H₅₂O₄

Peso molecular: 536.80

Ref: 4Z-H-101001

Hyperforin - solution in methanol

CAS: 11079-53-1

Lipophilic component of medicinal plant Hypericum perforatum (St John's wort) with anti-depressant activity. Uptake inhibitor of 5-HT, norephinephrine, dopamine, glutamate and GABA neurotransmitters. Also found to have anxiolytic, anti-proliferative and apoptosis-inducing properties.

Fórmula: C₃₅H₅₂O₄

Pureza: Min. 80 Area-%

Cor e Forma: Colorless Clear Liquid

Peso molecular: 536.78 g/mol

Ref: 3D-FH64889