CAS 11088-09-8

Wilforina

Descrição:

Wilforina, com o número CAS 11088-09-8, é um composto químico que pertence à classe dos alcaloides. É derivado principalmente da espécie vegetal Wilfordia ebracteata, conhecida por suas propriedades medicinais. O composto exibe uma gama de atividades biológicas, incluindo potenciais efeitos anti-inflamatórios e analgésicos, tornando-o de interesse na pesquisa farmacológica. Wilforina é caracterizado por sua complexa estrutura molecular, que contribui para sua atividade biológica. É tipicamente estudado por suas interações com vários alvos biológicos, incluindo enzimas e receptores. A solubilidade, estabilidade e reatividade do composto podem variar dependendo das condições ambientais, como pH e temperatura. Assim como muitos alcaloides, os perfis de segurança e toxicidade são cruciais para sua aplicação em química medicinal. Pesquisas em andamento visam elucidar ainda mais seus mecanismos de ação e potenciais usos terapêuticos, particularmente em contextos de medicina tradicional.

Fórmula: C₄₃H₄₉NO₁₈

InChI: InChI=1S/C43H49NO18/c1-21-16-17-29-28(15-12-18-44-29)39(52)55-19-40(7)30-31(56-23(3)46)35(58-25(5)48)42(20-54-22(2)45)36(59-26(6)49)32(60-38(51)27-13-10-9-11-14-27)34(61-37(21)50)41(8,53)43(42,62-40)33(30)57-24(4)47/h9-15,18,21,30-36,53H,16-17,19-20H2,1-8H3/t21-,30+,31+,32-,33+,34-,35+,36-,40-,41-,42+,43-/m0/s1

Chave InChI: InChIKey=ZOCKGJZEUVPPPI-QSNSFFMXSA-N

SMILES: C(OC(C)=O)[C@]12[C@@]34[C@H](OC(C)=O)[C@]([C@@](C)(O3)COC(=O)C=5C(CC[C@H](C)C(=O)O[C@]([C@]4(C)O)([C@H](OC(=O)C6=CC=CC=C6)[C@@H]1OC(C)=O)[H])=NC=CC5)([C@@H](OC(C)=O)[C@H]2OC(C)=O)[H]

Sinónimos:

• Evonimine, 8-(acetyloxy)-O2-benzoyl-O2-deacetyl-8-deoxo-, (8α)-
• 8,11-Epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine-5,17(18H)-dione, 10,13,22,23-tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-14-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-21-hydroxy-8,18,21-trimethyl-, (8R,9R,10R,11S,12S,13R,14R,15S,18S,21S,22S,23R)-
• (8R,9R,10R,11S,12S,13R,14R,15S,18S,21S,22S,23R)-10,13,22,23-Tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-14-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-21-hydroxy-8,18,21-trimethyl-8,11-epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine-5,17(18H)-dione
• Wilforine
• 8,11-Epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine-5,17(18H)-dione, 10,13,22,23-tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-14-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-21-hydroxy-8,18,21-trimethyl-, [8R-(8R*,9R*,10R*,11S*,12S*,13R*,14R*,15S*,18S*,21S*,22S*,23R*)]-

(8R,9R,10R,11S,12S,13R,14R,15S,18S,21S,22S,23R)-10,13,22,23-Tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-14-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-21-hydroxy-8,18,21-trimethyl-8,11-epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine-5,17(18H)-dione

CAS: 11088-09-8

Fórmula: C₄₃H₄₉NO₁₈

Pureza: %

Peso molecular: 867.8451

Ref: IN-DA008TNF

Wilforine

CAS: 11088-09-8

Wilforine

Pureza: ≥98%

Peso molecular: 867.85g/mol

Ref: 54-BUP03408

Wilforine

CAS: 11088-09-8

Fórmula: C₄₃H₄₉NO₁₈

Peso molecular: 867.85

Ref: 7W-GY2293

Wilforine

CAS: 11088-09-8

Wilforine has anti-inflammatory effect, which might be mediated by down-regulation of the expression of inflammatory factors TNF-α, IL-6 and NO. It also has insecticidal activity by inhibiting the Na+-K+-ATPase in the central nervous system.

Fórmula: C₄₃H₄₉NO₁₈

Pureza: 95%~99%

Cor e Forma: Powder

Peso molecular: 867.854

Ref: BP-BP1588

Wilforine

CAS: 11088-09-8

Wilforine: a sesquiterpene alkaloid from T. wilfordii, treats pulmonary fibrosis, has anti-inflammatory and insecticidal properties.

Fórmula: C₄₃H₄₉NO₁₈

Pureza: 98.67% - 99.85%

Cor e Forma: Solid

Peso molecular: 867.85

Ref: TM-T6S1049

Wilforine

CAS: 11088-09-8

Natural alkaloid

Fórmula: C₄₃H₄₉NO₁₈

Pureza: ≥ 95.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 867.86

Ref: 5G-83298

Wilforine

CAS: 11088-09-8

Wilforine is a natural diterpenoid alkaloid derived from the root of the *Tripterygium wilfordii* plant, a species widely explored for its bioactive compounds. As a member of the alkaloid family, Wilforine exhibits a complex chemical structure that underlies its biological activities. The mode of action of Wilforine is multifaceted, involving the modulation of immune system components and inhibition of various signaling pathways. This contributes to its anti-inflammatory and immunosuppressive properties.

Fórmula: C₄₃H₄₉NO₁₈

Pureza: Min. 96 Area-%

Cor e Forma: White Powder

Peso molecular: 867.85 g/mol

Ref: 3D-FW74254