CAS 111011-76-8

2-(benzil-fenil-amino)etil 5-(5,5-dimetil-2-oxo-1,3-dioxa-2$l^{5}-fosfaciclohex-2-il)-2,6-dimetil-4-(3-nitrofenil)-1,4-diidropiridina-3-carboxilato

Descrição:

A substância química conhecida como "2-(benzil-fenil-amino)etil 5-(5,5-dimetil-2-oxo-1,3-dioxa-2$l^{5}-fosfaciclohex-2-il)-2,6-dimetil-4-(3-nitrofenil)-1,4-diidropiridina-3-carboxilato," com o número CAS 111011-76-8, é um composto orgânico complexo que apresenta múltiplos grupos funcionais, incluindo um grupo amino, um carboxilato e uma parte nitrofenila. Sua estrutura sugere aplicações potenciais em química medicinal, particularmente no desenvolvimento de fármacos devido à presença do núcleo de diidropiridina, que muitas vezes está associado a bloqueadores de canais de cálcio. O componente fosfaciclohexano pode conferir propriedades únicas, como maior estabilidade ou bioatividade. A presença do grupo nitro indica potencial para maior reatividade ou interação com alvos biológicos. No geral, este composto exemplifica o design intrincado frequentemente encontrado no desenvolvimento de medicamentos, onde vários substituintes são incorporados estrategicamente para otimizar a eficácia e a seletividade. Estudos adicionais seriam necessários para elucidar suas atividades biológicas específicas e potenciais aplicações terapêuticas.

Fórmula: C₃₆H₄₅ClN₃O₈P

InChI: InChI=1/C34H38N3O7P.C2H6O.ClH/c1-24-30(33(38)42-19-18-36(28-15-9-6-10-16-28)21-26-12-7-5-8-13-26)31(27-14-11-17-29(20-27)37(39)40)32(25(2)35-24)45(41)43-22-34(3,4)23-44-45;1-2-3;/h5-17,20,31,35H,18-19,21-23H2,1-4H3;3H,2H2,1H3;1H

SMILES: CC1=C(C(c2cccc(c2)N(=O)=O)C(=C(C)N1)P1(=O)OCC(C)(C)CO1)C(=O)OCCN(Cc1ccccc1)c1ccccc1.CCO.Cl

Sinónimos:

• Hydrochloride
• Efonidipine hydrochloride ethanolate
• Efonidipine hydrochloride ethanol
• Efonidipine HCl ethanolate
• Ethanol, compd. with 2-(phenyl(phenylmethyl)amino)ethyl 5-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylate P-oxide monohydrochloride (1:1)
• Ethanol, compd. with 2-(phenyl(phenylmethyl)amino)ethyl 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylate monohydrochloride
• NZ 105 ethanolate
• Unii-3Br983K69O
• 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yl)-4-(3-nitrophenyl)-, 2-(phenyl(phenylmethyl)amino)ethyl ester, P-oxide, monohydrochloride
• 3-Pyridinecarboxylic acid, 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-(phenyl(phenylmethyl)amino)ethyl ester, monohydrochloride, compd. with ethanol (1
• 1)
• 2-[Benzyl(Phenyl)Amino]Ethyl 5-(5,5-Dimethyl-2-Oxido-1,3,2-Dioxaphosphinan-2-Yl)-2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydropyridine-3-Carboxylate

2-(benzyl(phenyl)amino)ethyl 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate compound with ethanol (1:1) hydrochloride

CAS: 111011-76-8

Fórmula: C₃₆H₄₅ClN₃O₈P

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 714.1846

Ref: IN-DA0082Z5

2-(Benzyl(Phenyl)Amino)Ethyl 5-(5,5-Dimethyl-2-Oxido-1,3,2-Dioxaphosphinan-2-Yl)-2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydropyridine-3-Carboxylate Ethanol Hydrochloride

CAS: 111011-76-8

2-(Benzyl(Phenyl)Amino)Ethyl 5-(5,5-Dimethyl-2-Oxido-1,3,2-Dioxaphosphinan-2-Yl)-2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydropyridine-3-Carboxylate Ethanol Hydrochloride

Pureza: 98%

Peso molecular: 714.18g/mol

Ref: 54-OR1027315

Efonidipine hydrochloride monoethanolate

CAS: 111011-76-8

Efonidipine hydrochloride monoethanolate

Pureza: ≥98%

Peso molecular: 714.18g/mol

Ref: 54-BUP06729

Efonidipine hydrochloride monoethanolate

CAS: 111011-76-8

Efonidipine HCl monoethanolate is a calcium blocker, boosts dehydroepiandrosterone sulfate in NCI-H295R cells.

Fórmula: C₃₆H₄₅ClN₃O₈P

Pureza: >99.99%

Cor e Forma: Solid

Peso molecular: 714.18

Ref: TM-T8401

Efonidipine Hydrochloride Monoethanolate

Produto Controlado

CAS: 111011-76-8

Fórmula: C₃₄H₃₈N₃O₇P·C₂H₆O·ClH

Cor e Forma: Neat

Peso molecular: 714.185

Ref: TR-E436005

Efonidipine hydrochloride monoethanolate

CAS: 111011-76-8

Efonidipine hydrochloride monoethanolate is a calcium channel blocker that blocks voltage-dependent calcium channels. It has been shown to reduce the incidence of bowel disease in humans, and is used to treat high blood pressure and heart failure. Efonidipine hydrochloride monoethanolate can be administered orally, intravenously, or by injection. The drug has been shown to have an effect on the concentration–time curve of maternal blood glucose levels in pregnant women with diabetes mellitus type 1. Efonidipine hydrochloride monoethanolate also may cause drug interactions with other drugs that are metabolized by cytochrome P450 enzymes. It will bind to matrix proteins in atherosclerotic lesions and inhibit light-induced fluorescence. This drug can be used as an analytical tool for measuring concentrations of various substances in the body fluids of patients with metabolic disorders such as diabetes mellitus type 1 or 2, hyperlipidaemia, hypertension

Fórmula: C₃₆H₄₅ClN₃O₈P

Pureza: Min. 95%

Peso molecular: 714.18 g/mol

Ref: 3D-BE179488