CAS 111470-99-6

besilato de amlodipina

Descrição:

besilato de amlodipina é um bloqueador de canais de cálcio usado principalmente no tratamento da hipertensão e da angina. É um pó cristalino branco a off-white que é solúvel em água e exibe uma faixa de pH de aproximadamente 6 a 8 em solução. A substância é um sal formado a partir de amlodipino, um derivado de dihidropiridina, e ácido benzenossulfônico, que melhora sua solubilidade e estabilidade. besilato de amlodipina atua inibindo a entrada de íons de cálcio no músculo liso vascular e no músculo cardíaco, levando à vasodilatação e à redução da pressão arterial. Sua farmacocinética indica uma longa meia-vida, permitindo a dosagem uma vez ao dia. O composto é tipicamente administrado por via oral e é bem absorvido, com concentrações plasmáticas máximas ocorrendo várias horas após a ingestão. Efeitos colaterais comuns podem incluir edema periférico, tontura e fadiga. Assim como com qualquer medicamento, é essencial considerar contraindicações e possíveis interações com outros medicamentos.

Fórmula: C₂₆H₃₁ClN₂O₈S

InChI: InChI=1/C20H25ClN2O5.CH4O3S/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21;1-5(2,3)4/h5-8,17,23H,4,9-11,22H2,1-3H3;1H3,(H,2,3,4)

Chave InChI: InChIKey=ZPBWCRDSRKPIDG-UHFFFAOYSA-N

SMILES: C(OCC)(=O)C=1C(C(C(OC)=O)=C(C)NC1COCCN)C2=C(Cl)C=CC=C2.S(=O)(=O)(O)C1=CC=CC=C1

Sinónimos:

• (±)-3-Ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate monobenzenesulfonate
• 2-[(2-Aminoethoxy)Methyl]-4-(2-Chlorophenyl)-3-Ethoxycarbonyl-5-Methoxycarbonyl-6-Methyl-1,4-Dihydropyridine Benzenesulfonate
• 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, benzenesulfonate (1:1)
• 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, monobenzenesulfonate
• 3-Ethyl 5-Methyl 2-[(2-Aminoethoxy)Methyl]-4-(2-Chlorophenyl)-6-Methyl-1,4-Dihydropyridine-3,5-Dicarboxylate
• 3-Ethyl 5-Methyl 2-[(2-Aminoethoxy)Methyl]-4-(2-Chlorophenyl)-6-Methyl-1,4-Dihydropyridine-3,5-Dicarboxylate Benzenesulfonate (1:1)
• 3-Ethyl 5-Methyl 2-[(2-Aminoethoxy)Methyl]-4-(2-Chlorophenyl)-6-Methyl-1,4-Dihydropyridine-3,5-Dicarboxylate Methanesulfonate (1:1)
• AM Arya 5
• Alkapress
• Alopres
• Amcard
• Amdepin
• Amdipin
• Amilo
• Amlodin
• Amlodin OD
• Amlodipine Besilate
• Amlodipine benzenesulfonate
• Amlodipine benzenesulfonate salt
• Amlodis
• Amlodopine Besilate
• Amlogard
• Amlopers 5
• Amlopin
• Amlor
• Amlosyn
• Amlovas
• Antacal
• Benzenesulfonic acid, compd. with 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate (1:1)
• Calchek
• Cardilopin
• Istin
• Lodipressin
• Lowrac
• Monopina
• Myodura
• Normodipine
• Norvas
• Norvasc
• Norvask
• Regcor
• Tensivask
• Uk 48340-26
• Vazkor
• Amlodipine besylate
• AMLODIPINE BESYLATE EPY(CRM STANDARD)
• 3,5-pyridinedicarboxylicacid,2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,
• AMLODIPINEBESYLATE(SUBJECTTOPATENTFREE)
• 4-dihydro-6-methyl-,3-ethyl-5-methylester,monobenzenesulfonate
• 2-[(2-AMINOETHOXY)-METHYL]-4-(2-CHLOROPHENYL)-1,4-DIHYDRO-6-METHYL-3,5-PYRIDINEDICARBOXYLIC ACID 3-ETHYL 5-METHYL ESTER BENZENE SULFONATE
• 2-[(2-aminoethoxy)-methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester benzene sulfonate

Amlodipine besylate, 98+%

CAS: 111470-99-6

An L-type calcium channel antagonist with potent antioxidant activity

Fórmula: C₂₀H₂₅ClN₂O₅·C₆H₅SO₃H

Pureza: 98+%

Peso molecular: 567.05

Ref: 02-J62164

Amlodipine Besilate

CAS: 111470-99-6

Cor e Forma: Light Yellow

Ref: 61-FOR0383.00

Amlodipine besilate

CAS: 111470-99-6

Amlodipine besilate

Fórmula: C₂₀H₂₅ClN₂O₅ / C₆H₆O₃S

Pureza: 72.0% / 99.9%

Cor e Forma: Light Yellow

Peso molecular: 408.1452 / 158.00377

Ref: 47-1221

AMLODIPINE BESILATE CRS

CAS: 111470-99-6

AMLODIPINE BESILATE CRS

Fórmula: C₂₀H₂₅ClN₂O₅

Cor e Forma: Added

Peso molecular: 408.8759

Ref: 41-Y0000049

AMLODIPINE FOR SYSTEM SUITABILITY CRS

CAS: 111470-99-6

AMLODIPINE FOR SYSTEM SUITABILITY CRS

Cor e Forma: Added

Ref: 41-Y0002505

AMLODIPINE FOR PEAK IDENTIFICATION CRS

CAS: 111470-99-6

AMLODIPINE FOR PEAK IDENTIFICATION CRS

Ref: 41-Y0001067

Amlodipine Besylate

CAS: 111470-99-6

Compounds containing an unfused pyridine ring in the structure, nesoi

Fórmula: C₂₀H₂₅ClN₂O₅·C₆H₆O₃S

Cor e Forma: White Light Yellow Powder

Peso molecular: 566.14896

Ref: 45-1029501

Amlodipine Besylate

CAS: 111470-99-6

Amlodipine Besylate(Amlodipine benzenesulfonate) is a long-lasting calcium channel blocker.

Fórmula: C₂₆H₃₁ClN₂O₈S

Pureza: 96.67% - 99.92%

Cor e Forma: White Powder

Peso molecular: 567.05

Ref: TM-T0231

Amlodipine Besylate

CAS: 111470-99-6

Fórmula: C₂₀H₂₅ClN₂O₅·C₆H₆O₃S

Cor e Forma: White To Off-White Solid

Peso molecular: 408.89 158.18

Ref: 4Z-A-083

Amlodipine Besylate

CAS: 111470-99-6

Amlodipine Besylate

Pureza: ≥95%

Peso molecular: 567.05g/mol

Ref: 54-BUP18487

Amlodipine N-Glucose

CAS: 111470-99-6

Fórmula: C₂₆H₃₅ClN₂O₁₀

Cor e Forma: Pale Yellow Solid

Peso molecular: 571.02

Ref: 4Z-A-0836

Amlodipine Besylate

CAS: 111470-99-6, 88150-42-9

Fórmula: C₂₀H₂₅ClN₂O₅·C₆H₅SO₃H

Pureza: >98.0%(HPLC)(qNMR)

Cor e Forma: White to Dark green powder to crystal

Peso molecular: 567.05

Ref: 3B-A2353

Amlodipine Besilate

CAS: 111470-99-6

Cor e Forma: Neat

Ref: 86-MM0383.00

Amlodipine besylate

Produto Controlado

CAS: 111470-99-6

Fórmula: C₂₀H₂₅ClN₂O₅·C₆H₆O₃S

Cor e Forma: Neat

Peso molecular: 567.05

Ref: 04-C10240500

Amlodipine besylate

CAS: 111470-99-6

Fórmula: C₂₀H₂₅ClN₂O₅·C₆H₅SO₃H

Peso molecular: 567.05

Ref: 7W-GP6347

Amlodipine Besilate RS

CAS: 111470-99-6

Cor e Forma: White Solid Crystalline Powder

Ref: 2K-1010000021

Amlodipine For Peak Identification CRS

CAS: 111470-99-6

Ref: ST-EA-Y0001067

Amlodipine Besylate

CAS: 111470-99-6

Applications Amlodipine Besylate is a dihydropyridine calcium channel blocker. Used as an antianginal and antihypertensive.
References Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986); Burges, R.A., et al.: J. Cardiovasc Pharmacol., 9, 110 (1987); Packer, M., et al.: N. Engl. J. Med., 335, 1107 (1996);

Fórmula: C₂₀H₂₅ClN₂O₅·C₆H₆O₃S

Cor e Forma: Light Yellow

Peso molecular: 567.05

Ref: TR-A633500

Amlodipine besylate

CAS: 111470-99-6

Inhibits L-type calcium channels; anti-hypertensive; antianginal

Fórmula: C₂₆H₃₁ClN₂O₈S

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 567.05 g/mol

Ref: 3D-FA17874

Amlodipine besylate - Bio-X ™

CAS: 111470-99-6

Amlodipine is a calcium channel blocker that is used to treat hypertension and angina. This drug inhibits the influx of calcium ions into both vascular smooth muscle and cardiac muscle.

Fórmula: C₂₀H₂₅ClN₂O₅•C₆H₆O₃S

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 567.05 g/mol

Ref: 3D-BA164162