CAS 1115-70-4

Cloridrato de metformina

Descrição:

Cloridrato de metformina é um agente antihiperglicêmico oral utilizado principalmente no manejo do diabetes mellitus tipo 2. Pertence à classe de medicamentos biguanidas e funciona diminuindo a produção hepática de glicose, aumentando a sensibilidade à insulina e melhorando a captação e utilização periférica de glicose. A substância aparece como um pó cristalino branco a off-white, que é solúvel em água, mas tem solubilidade limitada em solventes orgânicos. Sua fórmula química é C4H11N5·HCl, e tem um peso molecular de aproximadamente 165,63 g/mol. Cloridrato de metformina é tipicamente administrado em forma de comprimido e é conhecido por seu perfil de segurança favorável, com efeitos colaterais gastrointestinais sendo os mais comuns. Também está associado a um baixo risco de hipoglicemia quando usado isoladamente. Além disso, pesquisas indicaram benefícios potenciais além do controle glicêmico, incluindo proteção cardiovascular e gerenciamento de peso. Assim como qualquer medicamento, é essencial usar metformina sob supervisão médica, considerando contraindicações e interações potenciais com outros medicamentos.

Fórmula: C₄H₁₁N₅·ClH

InChI: InChI=1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H

Chave InChI: InChIKey=OETHQSJEHLVLGH-UHFFFAOYSA-N

SMILES: C(NC(=N)N)(N(C)C)=N.Cl

Sinónimos:

• 1,1-Dimethylbiguanide Hydrochloride
• 3-(Diaminomethylidene)-1,1-Dimethylguanidine Hydrochloride (1:1)
• Apo-Metformin
• Apophage
• Benofomin
• Biguanide, 1,1-dimethyl-, hydrochloride
• Biguanide, 1,1-dimethyl-, monohydrochloride
• Dabex
• Denkaform
• Dextin
• Diabefagos
• Diabetmim
• Diabetmin
• Diabetosan
• Diabex
• Diaformin
• Dialon
• Diformin
• Diformin Retard
• Dimefor
• Fornidd
• Fortamet
• Geamet
• Glifage
• Glucaminol
• Glucofago
• Glucoform
• Glucoformin
• Glucomet
• Glucomin
• Glucomine
• Gluconil
• Glucophage
• Glucophage 850
• Glucophage Forte
• Glucophage Retard
• Glucophage SR
• Glucophage XR
• Glucophage-Mite
• Gludepatic
• Glufor
• Gluformin
• Glumeformin
• Glumetza
• Glumin
• Glumin XR
• Glupermin
• Glyceriphage
• Glyciphage
• Glycon
• Glyformin
• Imidodicarbonimidic diamide, N,N-dimethyl-, hydrochloride (1:1)
• Imidodicarbonimidic diamide, N,N-dimethyl-, monohydrochloride
• La 6023
• Meguan
• Melbin
• Metforal
• Metformin Hydrochloride
• Metgluco
• Metomin
• Miformin
• N,N-Dimethylbiguanide hydrochloride
• N,N-Dimethylbiguanidine monohydrochloride
• N,N-Dimethylbiguanidinium chloride
• N¹,N¹-Dimethylbiguanide hydrochloride
• Neodipa
• Obimat-SR
• Orabet
• Riomet
• Siamformet

Metformin Hydrochloride

CAS: 1115-70-4, 657-24-9

Fórmula: C₄H₁₁N₅·HCl

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 165.63

Ref: 3B-M2009

1,1-Dimethylbiguanide hydrochloride

CAS: 1115-70-4

1,1-Dimethylbiguanide hydrochloride (HCl), or metformin HCl, 1115-70-4, is the salt form of the biguanide with antineoplastic and antihyperglycemic properties. Learn more.

Fórmula: C₄H₁₂ClN₅

Cor e Forma: White, Crystalline powder

Peso molecular: 165.63

Ref: 02-J63361

Metformin Hydrochloride 1.0 mg/ml in Methanol (as free base)

CAS: 1115-70-4

Cor e Forma: Single Solution

Ref: 61-AMP0056.00-01

Metformin Hydrochloride

CAS: 1115-70-4

Cor e Forma: Neat

Ref: 61-FOR0056.00

METFORMIN HYDROCHLORIDE CRS

CAS: 1115-70-4

METFORMIN HYDROCHLORIDE CRS

Fórmula: C₄H₁₂ClN₅

Cor e Forma: Powder

Peso molecular: 165.6246

Ref: 41-M0605000

Metformin for system suitability

CAS: 1115-70-4, 118632-64-7, 99-76-3

Metformin for system suitability

Cor e Forma: White

Ref: 47-1296

Metformin hydrochloride

CAS: 1115-70-4

Metformin hydrochloride

Fórmula: C₄H₁₂ClN₅

Pureza: 100%

Cor e Forma: White

Peso molecular: 165.07812

Ref: 47-227

Metformin Hydrochloride

CAS: 1115-70-4

Non-aromatic imines and their derivatives; salts thereof, nesoi

Fórmula: C₄H₁₁N₅·HCl

Cor e Forma: White Off-White Powder

Peso molecular: 129.10145

Ref: 45-1396309

Metformin hydrochloride (mM/ml)

CAS: 1115-70-4

Fórmula: C₄H₁₂ClN₅

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 165.6246

Ref: IN-DA003RHI

Metformin hydrochloride

CAS: 1115-70-4

Metformin hydrochloride (1,1-Dimethylbiguanide hydrochloride) is an AMPK activator. Metformin is used in type 2 diabetes research. Cost-effective and quality-assured.

Fórmula: C₄H₁₂ClN₅

Pureza: 97.53% - 99.97%

Cor e Forma: White Or Almost White Crystals Solid Crystalline

Peso molecular: 165.63

Ref: TM-T0740

1,1-Dimethylbiguanide hydrochloride

CAS: 1115-70-4

1,1-Dimethylbiguanide hydrochloride

Fórmula: C₄H₁₁N₅·ClH

Pureza: 97%

Cor e Forma: white solid

Peso molecular: 165.62g/mol

Ref: 54-OR322044

Metformin hydrochloride, EP grade

CAS: 1115-70-4

Fórmula: C₄H₁₁N₅·HCl

Pureza: 98.5 - 101.0 % (dried substance)

Cor e Forma: White or almost white crystals

Peso molecular: 165.62

Ref: 7W-GP1221

Metformin HCl

CAS: 1115-70-4

Fórmula: C₄H₁₁N₅·HCl

Cor e Forma: White To Off-White Solid

Peso molecular: 129.17 36.46

Ref: 4Z-M-422

Metformin hydrochloride

CAS: 1115-70-4

Fórmula: C₄H₁₁N₅·HCl

Pureza: (Titration) 98.0 - 102.0 % (dried basis)

Cor e Forma: White or almost white crystalline powder

Peso molecular: 165.62

Ref: 7W-GP2747

Metformin hydrochloride

CAS: 1115-70-4

Metformin hydrochloride

Pureza: ≥95%

Peso molecular: 165.63g/mol

Ref: 54-BUP17373

Metformin Hydrochloride

CAS: 1115-70-4

Fórmula: C₄H₁₁N₅·ClH

Cor e Forma: Neat

Peso molecular: 165.62

Ref: 04-C14956000

N1,N1-Dimethylbiguanide hydrochloride

CAS: 1115-70-4

Fórmula: C₄H₁₂ClN₅

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 165.63

Ref: 10-F463363

Metformin Hydrochloride

CAS: 1115-70-4

Fórmula: C₄H₁₁N₅·ClH

Cor e Forma: Neat

Peso molecular: 165.62

Ref: 86-MM0056.00

Metformin Impurity 13

CAS: 1115-70-4

Fórmula: C₄H₇N₅

Cor e Forma: White To Off-White Solid

Peso molecular: 125.14

Ref: 4Z-M-4226

Metformin Hydrochloride

Produto Controlado

CAS: 1115-70-4

Applications An oral hypoglycemic agent. Slows electron transport in the oxidation pathway in mitochondria. Has been reported to reverse Lupus symptoms in mice in conjunction with 2-deoxy-d-glucose (D239000). Metformin is a well-known type 2 diabetes treatment. Research shows that metformin may inhibit tumor growth both directly and indirectly. Studies indicate that metformin modulates the biology of aging. Metformin blocks the conversion of select substrates into glucose in a redox-dependent manner.
References Tucker, G.T., et al.: Brit. J. Clin. Pharmacol., 12, 235 (1981), DeFronzo, R.A., et al.: N. Engl. J. Med., 333, 541 (1995); Chem. and Eng. News, page 7, Feb. 23 (2015); Nir Barzilai et al., Cell Metabolism 23: 1060 June 14 (2016); Chem. and Eng. News, page 7, Feb. 23 (2015); Chem. and Eng. News, page 12, July 30 (2018)

Fórmula: C₄H₁₁N₅·ClH

Cor e Forma: White

Peso molecular: 165.62

Ref: TR-M258815

Metformin Hydrochloride

CAS: 1115-70-4

Fórmula: C₄H₁₁N₅HCl

Peso molecular: 129.17 : 36.46

Ref: ST-EA-CP-M3008

Metformin HCl - Bio-X ™

CAS: 1115-70-4

Metformin is a widely used anti-hyperglycemic (anti-diabetic) agent for the treatment of type 2 diabetes mellitus. This is due to it decreasing blood glucose by decreasing hepatic glucose product by activation of the AMP-activated protein kinase AMPK. Studies have also demonstrated Metformin to have anti-cancer activity, attributed to several mechanisms such as inhibition of mammalian target of rapamycin (mTOR), cancer stem cells and inflammation.

Fórmula: C₄H₁₁N₅•HCl

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 165.62 g/mol

Ref: 3D-BM164663

Metformin HCl

CAS: 1115-70-4

Metformin is a widely used anti-hyperglycemic (anti-diabetic) agent for the treatment of type 2 diabetes mellitus. This is due to it decreasing blood glucose by decreasing hepatic glucose product by activation of the AMP-activated protein kinase AMPK. Studies have also demonstrated Metformin to have anti-cancer activity, attributed to several mechanisms such as inhibition of mammalian target of rapamycin (mTOR), cancer stem cells and inflammation.

Fórmula: C₄H₁₂ClN₅

Cor e Forma: White Powder

Peso molecular: 165.62 g/mol

Ref: 3D-FM25131