CAS 112811-59-3

Gatifloxacina

Descrição:

Gatifloxacina é um antibiótico fluoroquinolona sintético caracterizado por sua atividade antibacteriana de amplo espectro. É utilizado principalmente para tratar várias infecções bacterianas, particularmente aquelas que afetam o trato respiratório e o sistema urinário. A estrutura química de Gatifloxacina inclui um núcleo bicíclico com um átomo de flúor, que aumenta sua potência contra bactérias gram-positivas e gram-negativas. Apresenta um mecanismo de ação que envolve a inibição da girase do DNA bacteriano e da topoisomerase IV, enzimas críticas para a replicação e reparo do DNA. Gatifloxacina é tipicamente administrado por via oral e é conhecido por sua boa biodisponibilidade. No entanto, tem sido associado a potenciais efeitos colaterais, incluindo distúrbios gastrointestinais e, em casos raros, danos nos tendões. Seu uso diminuiu em algumas regiões devido a preocupações de segurança e ao surgimento de resistência bacteriana. Assim como todos os antibióticos, é essencial usar Gatifloxacina de forma judiciosa para minimizar o risco de desenvolvimento de resistência e garantir sua eficácia no tratamento de infecções.

Fórmula: C₁₉H₂₂FN₃O₄

InChI: InChI=1S/C19H22FN3O4/c1-10-8-22(6-5-21-10)16-14(20)7-12-15(18(16)27-2)23(11-3-4-11)9-13(17(12)24)19(25)26/h7,9-11,21H,3-6,8H2,1-2H3,(H,25,26)

Chave InChI: InChIKey=XUBOMFCQGDBHNK-UHFFFAOYSA-N

SMILES: O(C)C1=C2N(C=C(C(O)=O)C(=O)C2=CC(F)=C1N3CC(C)NCC3)C4CC4

Sinónimos:

• 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-8-Methoxy-7-(3-Methyl-1-Piperazinyl)-4-Oxo-3-Quinolinecarboxylic Acid
• 1-Cyclopropyl-6-Fluoro-8-Methoxy-7-(3-Methylpiperazin-1-Yl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid
• 1-Cyclopropyl-6-fluoro-8-methoxy-1,4-dihydro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
• 1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid
• 1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-4-ium-1-yl)-4-oxoquinoline-3-carboxylate
• 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-
• Am 1155
• Bms 206584-01
• G-Cebran
• Gaity
• Gatiflo
• Gatifloxin
• Gatilox
• Gatiquin
• Gatispan
• Pd 135432
• Tequin
• Tymer
• Zymar

Gatifloxacin

CAS: 112811-59-3

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

Fórmula: C₁₉H₂₂FN₃O₄

Cor e Forma: White Light Yellow Powder

Peso molecular: 375.15943

Ref: 45-1288408

1-Cyclopropyl-6-fluoro-8-methoxy-1,4-dihydro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylicacid

CAS: 112811-59-3

Fórmula: C₁₉H₂₂FN₃O₄

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 375.3941

Ref: IN-DA001VAA

Gatifloxacin

CAS: 112811-59-3

Gatifloxacin (CG5501), a fourth-gen fluoroquinolone antibiotic, blocks bacterial DNA gyrase and topoisomerase IV.

Fórmula: C₁₉H₂₂FN₃O₄

Pureza: 99.50% - 99.85%

Cor e Forma: White Powder

Peso molecular: 375.39

Ref: TM-T1293

Gatifloxacin

CAS: 112811-59-3

Gatifloxacin

Pureza: ≥98%

Peso molecular: 375.39g/mol

Ref: 54-BUP18589

Gatifloxacin

CAS: 112811-59-3

Fórmula: C₁₉H₂₂FN₃O₄

Cor e Forma: White To Off-White Solid

Peso molecular: 375.40

Ref: 4Z-G-344

Gatifloxacin

CAS: 112811-59-3

Fórmula: C₁₉H₂₂FN₃O₄

Cor e Forma: Neat

Peso molecular: 375.39

Ref: 04-C13998600

1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

CAS: 112811-59-3

1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Pureza: 98%

Peso molecular: 375.39g/mol

Ref: 54-PC1528

Gatifloxacin

Produto Controlado

CAS: 112811-59-3

Applications An antibacterial.
References Bauernfeind, A.: J. Antimicro. Chemother., 40, 639 (1997), Fukuda, H., et al.: Antimicrob. Ag. Chemother., 42, 1917 (1998),

Fórmula: C₁₉H₂₂FN₃O₄

Cor e Forma: White To Off-White

Peso molecular: 375.39

Ref: TR-G250000

Gatifloxacin - Bio-X ™

CAS: 112811-59-3

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Fórmula: C₁₉H₂₂FN₃O₄

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 375.39 g/mol

Ref: 3D-BG300001

Gatifloxacin

CAS: 112811-59-3

Gatifloxacin is an antibiotic, which is a synthetic fluoroquinolone with broad-spectrum antibacterial activity. Its source lies in its chemical synthesis, designed to inhibit bacterial enzymes necessary for DNA replication. The mode of action involves the inhibition of bacterial DNA gyrase and topoisomerase IV, which are critical enzymes for bacterial DNA replication, transcription, and repair. This dual inhibitory mechanism disrupts bacterial cell division and growth, leading to the eventual eradication of susceptible bacterial strains.

Fórmula: C₁₉H₂₂FN₃O₄

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 375.39 g/mol

Ref: 3D-AC23649