CAS 112984-60-8

Ácido 6-Fluoro-1-Metil-4-Oxo-7-(1-Piperazinil)-4H-(1,3)-Tiazeto(3,2-Alfa)Quinolina-3-Carboxílico

Descrição:

Ácido 6-Fluoro-1-Metil-4-Oxo-7-(1-Piperazinil)-4H-(1,3)-Tiazeto(3,2-Alfa)Quinolina-3-Carboxílico, com número CAS 112984-60-8, é um composto sintético caracterizado por sua complexa estrutura heterocíclica, que inclui um núcleo de quinolina fundido com um anel de tiazol. A presença de um átomo de flúor na posição 6 e um grupo piperazina na posição 7 contribui para suas propriedades farmacológicas únicas. Este composto tipicamente exibe uma variedade de atividades biológicas, tornando-o de interesse na química medicinal, particularmente no desenvolvimento de agentes antimicrobianos ou antitumorais. Seu grupo funcional ácido carboxílico pode melhorar a solubilidade e a biodisponibilidade, enquanto o grupo oxo pode participar de várias reações químicas. As características estruturais do composto sugerem interações potenciais com alvos biológicos, que podem ser exploradas mais a fundo na pesquisa de descoberta de fármacos. No geral, esta substância representa uma classe de compostos que podem oferecer benefícios terapêuticos, embora aplicações específicas e eficácia exijam investigação experimental detalhada.

Fórmula: C₁₆H₁₆FN₃O₃S

InChI: InChI=1/C16H16FN3O3S/c1-8-20-11-7-12(19-4-2-18-3-5-19)10(17)6-9(11)14(21)13(16(22)23)15(20)24-8/h6-8,18H,2-5H2,1H3,(H,22,23)

Chave InChI: InChIKey=SUXQDLLXIBLQHW-UHFFFAOYSA-N

SMILES: CC1N2C=3C(C(=O)C(C(O)=O)=C2S1)=CC(F)=C(C3)N4CCNCC4

Sinónimos:

• 1H,4H-[1,3]Thiazeto[3,2-a]quinoline-3-carboxylic acid, 6-fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-
• 1H,4H-[1,3]Thiazeto[3,2-a]quinoline-3-carboxylicacid,6-fluoro-1-methyl-4-oxo-7-(1-piperazinyl)
• 6-Fluoro-1-Methyl-4-OXO-7-(1-PIPRAZINYL)-4H-(1,3)-THIAZETO(3,2-A)quinoline-3-CAR
• 6-Fluoro-1-Methyl-4-Oxo-7-(1-Piperazinyl)-4H-(1,3)Thiazeto(3,2-A)Quinoline-3-Carboxylicacid
• 6-Fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-4H-(1,3) -thiazeto (3,2-a)quinoline-3-carboxylic acid
• 6-Fluoro-1-methyl-4-oxo-7-piperazin-1-yl-4H-2-thia-8b-aza-cyclobuta[a] naphthalene-3-carboxylic acid
• 6-fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-1H,4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid
• 6-fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid
• Af 3013
• Nad 394
• Nm 394
• Pl-11
• Ulifloxacin
• Prulifloxacin Intermediate PL-11
• 6-Fluoro-1-methyl-7-(1-piperazinyl)-4-oxo-4H-(1,3)thiazeto(3,2-a)quinoline-3-carboxylic acid
• 6-FLUORO-7-PIPERAZINE-1-METHYL-4-OXY-[1,3]THIOAZACYCLIC[3,2-A]-QUINOLINE-3-CARBOXYLIC ACID
• PRULIFLOXACIN INTERMEDIATE 3
• 6-Fluoro-1-Methyl-4-Oxo-7-(1-Piperazinyl)-4H-(1,3)-Thiazeto(3,2-Alpha)Quinoline-3-Carboxylic Acid
• 6-Fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-4H-(1,3)-thiazeto
• 6-fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-4H-(1,3)-thiazeto(3,2-a)quinoline-3-carboxylic acid cas:(intermediate of prulifloxacin)
• 6-FLUORO-1-METHYL-4-OXO-7-(1-PIPRAZINYL)-1H,4H-(1,3)THIAZETO(3,2-A)QUINOLINE-3-CARBOXYLIC ACID

6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid

CAS: 112984-60-8

Fórmula: C₁₆H₁₆FN₃O₃S

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 349.3799

Ref: IN-DA0081N3

6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid

CAS: 112984-60-8

6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid

Pureza: 95%

Peso molecular: 349.39g/mol

Ref: 54-PC1002301

Ulifloxacin

CAS: 112984-60-8

Fórmula: C₁₆H₁₆FN₃O₃S

Peso molecular: 349.39

Ref: 4Z-U-041

Ulifloxacin

CAS: 112984-60-8

Applications A metabolite of Prulifloxacin (P838885). Ulifloxacin is a new quinolone antibiotic and it is effective against pneumonia.
References Kim, D., et al.: J. Pharm. Sci., 77, 200 (1988), Suzuki, T., et al.: Drug Metab. Dispos., 30, 1393 (2002), Sun, J., et al.: Eur. J. Pharm. Biopharm., 64, 238 (2006),

Fórmula: C₁₆H₁₆FN₃O₃S

Cor e Forma: Neat

Peso molecular: 349.38

Ref: TR-U700700

Ulifloxacin

CAS: 112984-60-8

Extensive research has been conducted on the antimicrobial activity of 6-fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-4H-(1,3)thiazeto(3,2a)quinoline-3-carboxylic acid (FPMT). FPMT is a levorotatory compound that is rapidly metabolized by esterases to 6FMT, which is also active against bacteria. FPMT inhibits bacterial growth, but does not inhibit mammalian cell growth. The main mechanism of action for FPMT is probably through its ability to inhibit the synthesis of bacterial DNA and RNA. This drug has been shown to be effective against sinusitis caused by bacterial rhinosinusitis and urinary tract infections caused by Escherichia coli and Pseudomonas aeruginosa. FPMT can be used as an alternative to prulifloxacin for the treatment of these types of infections

Fórmula: C₁₆H₁₆FN₃O₃S

Pureza: Min. 98 Area-%

Peso molecular: 349.38 g/mol

Ref: 3D-FF44006

Prulifloxacin Impurity 1

CAS: 112984-60-8

Fórmula: C₁₆H₁₆FN₃O₃S

Peso molecular: 349.38

Ref: ST-EA-CP-P202001

Ulifloxacin

CAS: 112984-60-8

Ulifloxacin is a useful organic compound for research related to life sciences. The catalog number is T65577 and the CAS number is 112984-60-8.

Fórmula: C₁₆H₁₆FN₃O₃S

Cor e Forma: Solid

Peso molecular: 349.38

Ref: TM-T65577