CAS 113-52-0

Cloridrato de imipramina

Descrição:

O cloridrato de imipramina é um antidepressivo tricíclico utilizado principalmente no tratamento do transtorno depressivo maior e de certos transtornos de ansiedade. Funciona inibindo a recaptação de neurotransmissores, particularmente norepinefrina e serotonina, aumentando assim sua disponibilidade na fenda sináptica. Esse mecanismo contribui para seus efeitos antidepressivos. A substância aparece como um pó cristalino branco a off-white e é solúvel em água, o que facilita sua administração em ambientes clínicos. O cloridrato de imipramina tem uma meia-vida relativamente longa, permitindo a dosagem uma vez ao dia em muitos casos. Os efeitos colaterais comuns podem incluir boca seca, sedação, ganho de peso e potenciais efeitos cardiovasculares, exigindo monitoramento cuidadoso, especialmente em pacientes com condições preexistentes. Devido ao seu perfil farmacológico, é classificado como um medicamento sob prescrição e deve ser usado sob supervisão médica. Além disso, é importante considerar possíveis interações com outros medicamentos, bem como o risco de sintomas de abstinência ao descontinuar. No geral, o cloridrato de imipramina continua sendo uma opção significativa na farmacoterapia da depressão e distúrbios relacionados.

Fórmula: C₁₉H₂₅ClN₂

InChI: InChI=1/C20H25N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-11,20H,7,12-15H2,1-2H3;1H

Chave InChI: InChIKey=XZZXIYZZBJDEEP-UHFFFAOYSA-N

SMILES: C(CCN(C)C)N1C=2C(CCC=3C1=CC=CC3)=CC=CC2.Cl

Sinónimos:

• 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-N,N-dimethylpropan-1-aminium chloride
• 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride (1:1)
• 5-(3-Dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepin hydrochloride
• 5-(3-Dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride
• 5H-Dibenz[b,f]azepine, 5-[3-(dimethylamino)propyl]-10,11-dihydro-, monohydrochloride
• 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride (1:1)
• 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-, monohydrochloride
• Apo-Imipramine
• Censtim
• Censtin
• Chrytemin
• Deprinol
• Depsol
• Dimipressin
• Dipd
• Dyna-Zina
• Efuranol
• Eupramin
• Feinalmin
• G 22355
• Imavate
• Imidobenzyle
• Imidol
• Imilanyle
• Imipramina, Clorhidrato
• Imipramine hydrochloride
• Imipramine monohydrochloride
• Imipramine, chlorhydrate
• Imipraminhydrochlorid
• Imiprin
• Imizin
• Imizine
• Imizinum
• Impril
• Intalpram
• Iramil
• Irmin
• Janimine
• Melipramin
• Melipramine hydrochloride
• N-(3-Dimethylaminopropyl)iminodibenzyl hydrochloride
• N-(γ-Dimethylaminopropyl)iminodibenzyl hydrochloride
• Novo-pramine
• Praminil
• Presamine
• Promiben
• Pryleugan
• SK-Pramine
• Surplix
• Teperine
• Timolet
• Tipramine
• Tofranil
• Tofranile
• cocapimipramine25
• f)azepine,10,11-dihydro-5-(3-(dimethylamino)propyl)-5h-dibenz(hydrochlor
• chimoreptin
• f)azepine-5-propanamine,10,11-dihydro-n,n-dimethyl-5h-dibenz(monohydroch
• 10,11-DIHYDRO-N,N-DIMETHYL-5H-DIBENZ[B,F]AZEPINE-5-PROPANAMINE HYDROCHLORIDE
• f)azepine,5-(3-(dimethylamino)propyl)-10,11-dihydro-5h-dibenz(monohydrochloride
• IMIPRAMINE HCL
• f)azepine,5-(3-(dimethylamino)propyl)-10,11-dihydro-5h-dibenz(monohydrochl
• LABOTEST-BB LT00452014
• 10,11-Dihydro-N,N-dimithyl-5,H-dibenz[b,f]azepine-5-propanamine
• 5-(3-dimethylaminopropyl)-10,11-dihydro-5h-dibenz(b,f)azepinehydrochloride
• 10,11-dihydro-5-(3-(dimethylamino)propyl)-5h-dibenz[b,f]azepine hydrochloride
• 10,11-DIHYDRO-N,N-DIMETHYL-DIBENZ[B,F]AZEPINE-5-PROPANAMINE HYDROCHLORIDE
• antideprinhydrochloride

Imipramine Hydrochloride

CAS: 113-52-0

Applications Tricyclic antidepressant; inhibits the serotonin and norepinephrine transporters. Has little effect on the dopamine transporter.
References Wood, M.D., et al.: Neuropharmacology, 26, 1081 (1987), Casis, O., et al.: J. Cardiovasc. Pharmacol., 32, 521 (1998), Linner, L., et al.: Biol. Psychiatry, 46, 766 (1999), Teschemacher, et al.: Br. J. Pharmacol., 128, 479 (1999),

Fórmula: C₁₉H₂₄N₂·ClH

Cor e Forma: Off White

Peso molecular: 316.87

Ref: TR-I465980

Clomipramine EP Impurity B

CAS: 113-52-0

Fórmula: C₁₉H₂₄N₂HCl

Peso molecular: 280.4 : 36.5

Ref: ST-EA-CP-C30002

Imipramine HCl - Bio-X ™

Produto Controlado

CAS: 113-52-0

Imipramine is a drug that belongs to the class of tricyclic antidepressant drugs. It is used in the treatment of depression and childhood enuresis. It is a potent inhibitor of serotonin and norepinephrine reuptake. Imipramine blocks D-2 receptors, H1 receptors, α-1 and α-2 adrenergic receptors and muscarinic receptors. Also, it is indicated for dysthymia, attention-deficit disorders, agoraphobia and it is effective in treating anxiety and panic disorders.

Fórmula: C₁₉H₂₄N₂•HCl

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 316.87 g/mol

Ref: 3D-BI164574

Imipramine hydrochloride

Produto Controlado

CAS: 113-52-0

Imipramine hydrochloride is a hydrochloride salt form of imipramine, a surface active tricyclic drug, a potent inhibitor of serotonin and norepinephrine reuptake. It has a greater affinity for the serotonin and it has more anticholinergic side effects which can be helpful in treating enuresis. Imipramine blocks D-2 receptors, H1 receptors, alpha 1 and alpha 2 adrenergic receptors and muscarinic receptors. It is used for therapy of depression (major and bipolar) and nocturnal enuresis in children. Also it is indicated for dysthymia, attention-deficit disorders, agoraphobia and it is effective in treating anxiety and panic disorders.

Fórmula: C₁₉H₂₅ClN₂

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 316.87 g/mol

Ref: 3D-FI24561