CAS 113-80-4

argiprestocina

Descrição:

argiprestocina, com o número CAS 113-80-4, é um peptídeo sintético que atua como vasodilatador e é utilizado principalmente em ambientes de pesquisa. É conhecido por sua capacidade de imitar a ação de certos peptídeos endógenos, influenciando o relaxamento do músculo liso vascular e potencialmente impactando a dinâmica do fluxo sanguíneo. A substância é caracterizada por sua sequência específica de aminoácidos, que contribui para sua atividade biológica. argiprestocina é frequentemente estudado por seus efeitos na função cardiovascular e suas potenciais aplicações terapêuticas em condições relacionadas à saúde vascular. Como peptídeo, é tipicamente solúvel em soluções aquosas e pode exigir manuseio cuidadoso para manter sua estabilidade. Seu perfil farmacológico inclui interações com receptores específicos, levando a várias respostas fisiológicas. No entanto, informações detalhadas sobre sua segurança, eficácia e aplicações clínicas são limitadas, uma vez que é utilizado principalmente em contextos experimentais em vez de uso clínico generalizado.

Fórmula: C₄₃H₆₇N₁₅O₁₂S₂

InChI: InChI=1/C43H67N15O12S2/c1-3-21(2)34-41(69)53-26(12-13-31(45)60)37(65)55-28(17-32(46)61)38(66)56-29(20-72-71-19-24(44)35(63)54-27(39(67)57-34)16-22-8-10-23(59)11-9-22)42(70)58-15-5-7-30(58)40(68)52-25(6-4-14-50-43(48)49)36(64)51-18-33(47)62/h8-11,21,24-30,34,59H,3-7,12-20,44H2,1-2H3,(H2,45,60)(H2,46,61)(H2,47,62)(H,51,64)(H,52,68)(H,53,69)(H,54,63)(H,55,65)(H,56,66)(H,57,67)(H4,48,49,50)/t21-,24-,25-,26-,27-,28-,29-,30-,34-/m0/s1

SMILES: CC[C@H](C)[C@H]1C(=N[C@@H](CCC(=N)O)C(=N[C@@H](CC(=N)O)C(=N[C@@H](CSSC[C@@H](C(=N[C@@H](Cc2ccc(cc2)O)C(=N1)O)O)N)C(=O)N1CCC[C@H]1C(=N[C@@H](CCCNC(=N)N)C(=NCC(=N)O)O)O)O)O)O

Sinónimos:

• Argiprestocin [INN]
• (Arg(sup 8))oxytocin
• 8-Arg-vasotocin
• 8-Arginine vasotocin
• 8-L-Arginineoxytocin
• Arg-vasotocin
• Arginine vasotocin
• Argiprestocina
• Argiprestocina [INN-Spanish]
• Argiprestocine
• Argiprestocine [INN-French]
• Argiprestocinum
• Argiprestocinum [INN-Latin]
• Brn 4902334
• Natriuretic hormone (ox pineal)
• Unii-W6S6Ury8Of
• 8-Arginineoxytocin
• Oxytocin, 8-L-arginine-
• 1-{[(4R,7S,10S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}prolyl-N~5~-(diaminomethylidene)-L-ornithylglycinamide
• 1-{[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-N~5~-(diaminomethylidene)-L-ornithylglycinamide
• Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Arg-Gly-Nh2
• Argiprestocin
• 8-l-arginine-oxytoci
• [ARG8]-VASOTOCIN
• H-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Arg-Gly-NH2, (Disulfide bond)
• CYS-TYR-ILE-GLN-ASN-CYS-PRO-ARG-GLY-NH2 USP/EP/BP
• H-CYS-TYR-ILE-GLN-ASN-CYS-PRO-ARG-GLY-NH2, CYS1,6, CYCLIC
• CYS-TYR-ILE-GLN-ASN-CYS-PRO-ARG-GLY-NH2(DISULFIDE BRIDGE:CYS1-CYS6)
• 8-argininevasotocin
• 1-[(1R,4S,7S,13S,16R)-16-amino-4-(2-amino-2-oxoethyl)-7-(3-amino-3-oxopropyl)-10-[(2S)-butan-2-yl]-13-[(4-hydroxyphenyl)methyl]-3,6,9,12,15-pentaoxo-18,19-dithia-2,5,8,11,14-pentazacycloicosane-1-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
• 1-[[(1R,4S,7S,13S,16R)-16-azanyl-4-(2-azanyl-2-oxo-ethyl)-7-(3-azanyl-3-oxo-propyl)-10-[(2S)-butan-2-yl]-13-[(4-hydroxyphenyl)methyl]-3,6,9,12,15-pentaoxo-18,19-dithia-2,5,8,11,14-pentazacycloicos-1-yl]carbonyl]-N-[(2S)-1-[(2-azanyl-2-oxo-ethyl)amino]-5-[bis(azanyl)methylideneamino]-1-oxo-pentan-2-yl]pyrrolidine-2-carboxamide
• 1-[(1R,4S,7S,13S,16R)-16-amino-4-(2-amino-2-keto-ethyl)-7-(3-amino-3-keto-propyl)-13-(4-hydroxybenzyl)-3,6,9,12,15-pentaketo-10-[(1S)-1-methylpropyl]-18,19-dithia-2,5,8,11,14-pentazacycloicosane-1-carbonyl]-N-[(1S)-1-[(2-amino-2-keto-ethyl)carbamoyl]-4-guanidino-butyl]pyrrolidine-2-carboxamide
• [ARG8]-VASOTOCIN (FROG, CHICKEN)
• VASOTOCIN ARG 8
• (arg(sup8))oxytocin
• [Arg8]-Vasotocin trifluoroacetate
• H-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Cys1-Cys6)
• VASOTOCIN, [ASU16,ARG8]
• CYIQNCPRG-NH2
• H-CYS-TYR-ILE-GLN-ASN-CYS-PRO-ARG-GLY-NH2

(Arg⁸)-Vasotocin (Salt form acetate)

CAS: 113-80-4

Non-mammalian Arg-vasopressin/oxytocin analog.

Fórmula: C₄₃H₆₇N₁₅O₁₂S₂

Pureza: 98.7%

Cor e Forma: White Whitish Powder

Peso molecular: 1050.23

Ref: 01-4100576

(Arg⁸)-Vasotocin (Salt form trifluoroacetate)

CAS: 113-80-4

Vasotocin (AVT, argiprestocin) is the vasopressin/oxytocin analog produced in birds, amphibians and fish. AVT shows antidiuretic as well as reproductive activities.

Fórmula: C₄₃H₆₇N₁₅O₁₂S₂

Pureza: 98.0%

Cor e Forma: White

Peso molecular: 1050.23

Ref: 01-4031338

[Arg8]-Vasotocin

CAS: 113-80-4

[Arg8]-Vasotocin is a hormone present in the neurohypophysis of nonmammalian vertebrates that is related to vasopressin and oxytocin.

Fórmula: C₄₃H₆₇N₁₅O₁₂S₂

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 1050.22

Ref: TM-TP1400

[Arg8]-Vasotocin trifluoroacetate

CAS: 113-80-4

Vasotocin is a peptide hormone that regulates a variety of physiological processes, including blood pressure, water permeability, and locomotor activity. Vasotocin is synthesized from the precursor arginine vasotocin (AVT) by the enzyme polypeptide chain elongation. AVT can bind to two different receptors: one that is inhibitory and one that is excitatory. The inhibitory receptor for AVT can be activated by vasopressin or oxytocin, while the excitatory receptor for AVT can be activated by atrial natriuretic peptide. Activation of both receptors leads to increased blood flow and decreased blood pressure. Vasotocin has been shown to have an inhibitory effect on the polymerase chain reaction in human serum and to have a model system in rats.

Fórmula: C₄₃H₆₇N₁₅O₁₂S₂

Pureza: Min. 95%

Peso molecular: 1,050.22 g/mol

Ref: 3D-FA73663