CAS 114-25-0

Biliverdina

Descrição:

Biliverdina é um pigmento biliar tetrapirrólico verde que é um produto da degradação do heme, formado principalmente a partir da decomposição da hemoglobina. É caracterizado por sua cor verde, que se deve ao seu sistema de ligações duplas conjugadas, permitindo-lhe absorver luz no espectro visível. Biliverdina é solúvel em água e tem uma fórmula molecular de C33H34N4O6, com um peso molecular de aproximadamente 582,6 g/mol. Desempenha um papel significativo em vários processos biológicos, incluindo atuar como um antioxidante e participar da regulação das funções celulares. Biliverdina também é um precursor da bilirrubina, outro pigmento biliar importante. Em termos de estabilidade, Biliverdina pode ser sensível à luz e a mudanças de pH, o que pode afetar sua estrutura e reatividade. Sua presença em sistemas biológicos está frequentemente associada à função hepática e pode ser indicativa de certas condições médicas quando encontrada em concentrações anormais. No geral, Biliverdina é um composto importante em bioquímica e medicina, refletindo os complexos processos do metabolismo do heme.

Fórmula: C₃₃H₃₄N₄O₆

InChI: InChI=1/C33H34N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-15,35H,1-2,9-12H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-,28-15-

Chave InChI: InChIKey=QBUVFDKTZJNUPP-BBROENKCSA-N

SMILES: C(\C1=C(CCC(O)=O)C(C)=C(/C=C\2/C(C=C)=C(C)C(=O)N2)N1)=C3/C(CCC(O)=O)=C(C)C(/C=C\4/C(C)=C(C=C)C(=O)N4)=N3

Sinónimos:

• 21H-Biline-8,12-dipropanoic acid, 3,18-diethenyl-1,19,22,24-tetrahydro-2,7,13,17-tetramethyl-1,19-dioxo-
• 3,18-Diethenyl-1,19,22,24-tetrahydro-2,7,13,17-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid
• 3-[(2Z)-2-[[3-(2-carboxyethyl)-4-methyl-5-[(Z)-(4-methyl-5-oxo-3-vinyl-pyrrol-2-ylidene)methyl]-1H-pyrrol-2-yl]methylene]-4-methyl-5-[(Z)-(3-methyl-5-oxo-4-vinyl-pyrrol-2-ylidene)methyl]pyrrol-3-yl]propanoic acid
• 3-[2-[(E)-[(5E)-3-(2-carboxyethyl)-4-methyl-5-[(3-methyl-5-oxo-4-vinyl-pyrrol-2-yl)methylene]pyrrol-2-ylidene]methyl]-4-methyl-5-[(E)-(4-methyl-5-oxo-3-vinyl-pyrrol-2-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
• 3-[2-[(Z)-[(5E)-3-(2-carboxyethyl)-4-methyl-5-[(3-methyl-5-oxo-4-vinyl-pyrrol-2-yl)methylene]pyrrol-2-ylidene]methyl]-4-methyl-5-[(Z)-(4-methyl-5-oxo-3-vinyl-pyrrol-2-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
• 3-[2-[(Z)-[(5Z)-3-(2-carboxyethyl)-4-methyl-5-[(3-methyl-5-oxo-4-vinyl-pyrrol-2-yl)methylene]pyrrol-2-ylidene]methyl]-4-methyl-5-[(Z)-(4-methyl-5-oxo-3-vinyl-pyrrol-2-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
• 3-[2-[[3-(2-carboxyethyl)-4-methyl-5-[(3-methyl-5-oxo-4-vinyl-pyrrol-2-yl)methylene]pyrrol-2-ylidene]methyl]-4-methyl-5-[(4-methyl-5-oxo-3-vinyl-pyrrol-2-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
• Biline-8,12-dipropionic acid, 1,19,22,24-tetrahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-
• Biline-8,12-dipropionic acid, 1,19,22,24-tetrahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl- (8CI)
• Biliverdin IXalpha
• Biliverdin IXα
• Biliverdina
• Biliverdine
• Biliverdine (VAN)
• Biliverdine dihydrochloride
• Dehydrobilirubin
• Nsc 62793
• Oocyan
• Protobiliverdin IXα
• Pyrrole-3-propionic acid, 2-[[3-(2-carboxyethyl)-4-methyl-5-[(3-methyl-5-oxo-4-vinyl-3-pyrrolin-2-ylidene)methyl]-2H-pyrrol-2-ylidene]methyl]-4-methyl-5-[(4-methyl-5-oxo-3-vinyl-3-pyrrolin-2-ylidene)methyl]-
• Uteroverdine
• α-Biliverdin
• Biliverdin
• 3-[2-[(Z)-[(5E)-3-(2-carboxyethyl)-5-[(4-ethenyl-3-methyl-5-oxo-pyrrol-2-yl)methylidene]-4-methyl-pyrrol-2-ylidene]methyl]-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
• 3-[2-[(E)-[(5E)-3-(2-carboxyethyl)-5-[(4-ethenyl-3-methyl-5-oxo-pyrrol-2-yl)methylidene]-4-methyl-pyrrol-2-ylidene]methyl]-5-[(E)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
• ocyan
• 3,18-Diethenyl-1,19,22,24-tetrahydro-2,7,13,17-tetrametyl-1,19-dioxo-21H-biline-8,12-dipropanoic Acid

3,18-Diethenyl-1,19,22,24-tetrahydro-2,7,13,17-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid

CAS: 114-25-0

Fórmula: C₃₃H₃₄N₄O₆

Pureza: 70%

Cor e Forma: Solid

Peso molecular: 582.6463

Ref: IN-DA0038B8

Biliverdine

CAS: 114-25-0

Stability Light Sensitive
Applications Biliverdine is a precursor of Bilirubin. Biliverdine is formed in the body from hemoglobin. The bile of amphibians and of birds contains Biliverdine only. It is also an inhibitor for hepatitis C virus.
References Lemberg et al.: Biochem. J., 35, 363 (1941); Gutierrez-Grobe, Y. et al.: Annals. Hepatol., 10, 105 (2011);

Fórmula: C₃₃H₃₄N₄O₆

Cor e Forma: Dark Green To Black

Peso molecular: 582.65

Ref: TR-B386400

Biliverdine-d4 (Major, may contain up to 3% d0) (Technical Grade)

Produto Controlado

CAS: 114-25-0

Applications Labelled Biliverdine is a precursor of Bilirubin. Biliverdine is formed in the body from hemoglobin. The bile of amphibians and of birds contains Biliverdine only. It is also an inhibitor for hepatitis C virus.
References Lemberg et al.: Biochem. J., 35, 363 (1941); Gutierrez-Grobe, Y. et al.: Annals. Hepatol., 10, 105 (2011);

Fórmula: C₃₃H₃₀D₄N₄O₆

Pureza: >90%

Cor e Forma: Neat

Peso molecular: 586.67

Ref: TR-B386402

Biliverdine

CAS: 114-25-0

Biliverdine is a fluorescent probe that selectively binds to bilirubin and other hydroxycinnamic acids in tissue. Biliverdine can be used to measure the oxidative injury of tissues as well as the activity of enzymes involved in the metabolism of these compounds. The use of biliverdin with other fluorescent probes has been shown to improve the sensitivity and specificity for detecting oxidative injury. Biliverdin has also been shown to have anti-inflammatory properties, which may be due to its ability to inhibit the production of growth factor-β1 and 4-hydroxycinnamic acid.

Fórmula: C₃₃H₃₄N₄O₆

Pureza: Min. 70 Area-%

Cor e Forma: Green Powder

Peso molecular: 582.65 g/mol

Ref: 3D-FB18596

Biliverdin

CAS: 114-25-0

Biliverdin, produced through the oxidation of bilirubin, can also be synthesized through a non-protoporphyrin pathway in Corynebacterium glutamicum [1].

Fórmula: C₃₃H₃₄N₄O₆

Cor e Forma: Solid

Peso molecular: 582.65

Ref: TM-T84736