CAS 114-49-8

Bromidrato de escopolamina

Descrição:

Bromidrato de escopolamina é um alcaloide tropano derivado de plantas da família Solanaceae, particularmente da planta de beladona. É um pó cristalino branco a off-white que é solúvel em água e álcool, tornando-o adequado para várias formulações farmacêuticas. A substância atua principalmente como um agente anticolinérgico, bloqueando a ação da acetilcolina no sistema nervoso, o que a torna eficaz no tratamento de enjoo, náuseas e vômitos. Bromidrato de escopolamina também é usado em ambientes pré-operatórios para reduzir a salivação e as secreções. Seus efeitos farmacológicos incluem sedação, amnésia e relaxamento muscular, mas também pode causar efeitos colaterais como boca seca, visão turva e sonolência. Devido ao seu potencial de abuso e ao risco de efeitos colaterais graves, seu uso é cuidadosamente monitorado em ambientes clínicos. Assim como qualquer medicamento, é essencial usar Bromidrato de escopolamina sob a orientação de um profissional de saúde para garantir segurança e eficácia.

Fórmula: C₁₇H₂₂BrNO₄

InChI: InChI=1/C17H21NO4.BrH/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;/h2-6,11-16,19H,7-9H2,1H3;1H/t11-,12-,13+,14?,15-,16?;/m1./s1

Chave InChI: InChIKey=WTGQALLALWYDJH-MOUKNHLCSA-N

SMILES: CN1[C@@]2([C@]3([C@](O3)([C@]1(C[C@@H](OC([C@H](CO)C4=CC=CC=C4)=O)C2)[H])[H])[H])[H].Br

Sinónimos:

• (-)-Scopolamine bromide
• (-)-Scopolamine, HBr
• (1S,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0~2,4~]non-7-yl 3-hydroxy-2-phenylpropanoate hydrobromide (1:1)
• 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropan-3α-ol, 6β,7β-epoxy-, (-)-tropate (ester), hydrobromide
• 3-Oxa-9-azatricyclo[3.3.1.0^2,4]nonane, benzeneacetic acid deriv.
• 9-Methyl-3-Oxa-9-Azatricyclo[3.3.1.0~2,4~]Non-7-Yl 3-Hydroxy-2-Phenylpropanoate Hydrobromide (1:1)
• 9-Methyl-3-Oxa-9-Azatricyclo[3.3.1.0~2,4~]Non-7-Yl 3-Hydroxy-2-Phenylpropanoate Hydrochloride
• Beldavrin
• Benzeneacetic acid, α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0^2,4]non-7-yl ester, hydrobromide (1:1), (αS)-
• Benzeneacetic acid, α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0^2,4]non-7-yl ester, hydrobromide, (αS)-
• Benzeneacetic acid, α-(hydroxymethyl)-, 9-methyl-3-oxa-9-azatricyclo[3.3.1.0^2,4]non-7-yl ester, hydrobromide, [7(S)-(1α,2β,4β,5α,7β)]-
• Euscopol
• Hydroscine hydrobromide
• Hyocine f hydrobromide
• Hyoscine Hydrobromide
• Hyoscine bromide
• Hysco
• Isoscopil
• Kwells
• Scopamin
• Scopolamine hydrobromide
• Scopolaminium bromide
• Scopolammonium bromide
• Scopos
• Sea Legs
• Sereen
• Triptone
• Wellcome Brand Scopolamine hydrobromide Injection
• benzeneacetic acid, alpha-(hydroxymethyl)-, bromide, (1S,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0~2,4~]non-7-yl ester, (alphaS)-
• l-Hyoscine hydrobromide
• l-Scopolamine hydrobromide
• Benzeneacetic acid, α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, hydrobromide (1:1), (αS)-
• Benzeneacetic acid, α-(hydroxymethyl)-, 9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, hydrobromide, [7(S)-(1α,2β,4β,5α,7β)]-
• Benzeneacetic acid, α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, hydrobromide, (αS)-
• scopolamine hydrobromide trihydrate
• 1αH,5αH-Tropan-3α-ol, 6β,7β-epoxy-, (-)-tropate (ester), hydrobromide
• HYOSCINE
• ),hydrobromide
• (A,S)-ALPHA-(HYDROXYMETHYL)BENZENEACETIC ACID (1A,2B,4B,5A,7B)-9-METHYL-3-OXA-9-AZATRICYCLO[3.3.1.02,4]NON-7-YL ESTER HYDROBROMIDE
• alpha-(hydroxymethyl)-benzeneaceticaci9-methyl-3-oxa-9-azatricyclo[3.3.1.
• SCOPINE TROPATE HYDROBROMIDE
• HYOSCINE HBR
• SCOPOLOAMINE HYDROBROMIDE
• .alpha.-(hydroxymethyl)-,9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-ylester,hydrobromide,[7(Benzeneaceticacid
• hydroscinehydrobromide
• ATROSCINE HYDROBROMIDE
• hyocinefhydrobromide
• 5-alpha-h-tropan-3-alpha-ol,6-beta,7-beta-epoxy-1-alpha-(-)-tropate(ester
• (-)-scopolaminebromide

Scopolamine HBr (Hyoscine HBr)

CAS: 114-49-8

Fórmula: C₁₇H₂₁NO₄·HBr

Cor e Forma: White To Off-White Solid

Peso molecular: 303.36 80.91

Ref: 4Z-S-012

Scopolamine hydrobromide

CAS: 114-49-8

Fórmula: C₁₇H₂₂BrNO₄

Pureza: 95%~99%

Peso molecular: 384.27

Ref: BP-BP1274

Scopolamine Hydrobromide Trihydrate

CAS: 114-49-8, 51-34-3, 6533-68-2

Fórmula: C₁₇H₂₁NO₄·HBr·3H₂O

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 438.32

Ref: 3B-S0021

(1S,2R)-9-Methyl-3-oxa-9- azatricyclo[3.3.1.02,4]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate trihydrate hydrobromide

CAS: 114-49-8

(1S,2R)-9-Methyl-3-oxa-9- azatricyclo[3.3.1.02,4]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate trihydrate hydrobromide

Pureza: ≥95%

Peso molecular: 438.31g/mol

Ref: 54-OR310495

Scopolamine hydrobromide

CAS: 114-49-8

Natural alkaloid

Fórmula: C₁₇H₂₁NO₄HBr

Pureza: ≥ 95.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 384.27

Ref: 5G-80046

Scopolamine Hydrobromide Hydrate

Produto Controlado

CAS: 114-49-8, 6533-68-2

Applications Scopolamine Hydrobromide Hydrate is an acetylcholine antagonist. Used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant. Neuroprotective & Neuroresearch Product.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Brand, J.J., et al.: Lancet, 2, 232 (1970); Bowles, J.B., et al.: Anaesthesia, 34, 476 (1979); Clissold, S.P., et al.: Drugs, 29, 189 (1985); Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 19, 477 (1990);

Fórmula: C₁₇H₂₁NO₄·HBr·xH₂O

Cor e Forma: White Solid

Peso molecular: 384.26

Ref: TR-S200000

Scopolamine-13C, D3 Hydrobromide

Produto Controlado

CAS: 114-49-8

Applications Scopolamine-13C, d3 Hydrobromide, is the labeled analogue of Scopolamine-d3 Hydrobromide (S200002), an acetylcholine antagonist, used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Brand, J.J., et al.: Lancet, 2, 232 (1970), Bowles, J.B., et al.: Anaesthesia, 34, 476 (1979), Clissold, S.P., et al.: Drugs, 29, 189 (1985), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 19, 477 (1990),

Fórmula: C₁₆₁₃CH₁₉D₃BrNO₄

Cor e Forma: Off-White

Peso molecular: 388.28

Ref: TR-S200003

Scopolamine hydrobromide

CAS: 114-49-8

Scopolamine hydrobromide is an anticholinergic medication, which is a derivative of tropane alkaloids sourced primarily from Solanaceae family plants, such as Hyoscyamus niger and Datura stramonium. Its mode of action involves competitive inhibition of acetylcholine at muscarinic receptors in the central and peripheral nervous systems. This blocking effect impedes parasympathetic nerve impulses, leading to diminished activity in smooth muscles and glandular secretions.

Fórmula: C₁₇H₂₁NO₄·HBr

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 384.26 g/mol

Ref: 3D-FA66263