CAS 114056-26-7

vasotocina, (ácido beta-mercapto-beta,beta-ciclopentametileno-propiónico)-O-metil-Tyr(2)-Thr(4)-Orn(8)-Tyr(9)-NH2

Descrição:

A vasotocina é um hormônio peptídico que desempenha um papel significativo em vários processos fisiológicos, particularmente na regulação do equilíbrio hídrico e da pressão arterial. Está estruturalmente relacionada à vasopressina e à ocitocina, apresentando uma estrutura cíclica que melhora sua estabilidade e atividade biológica. A sequência específica de aminoácidos na vasotocina inclui modificações como o ácido beta-mercapto-beta,beta-ciclopentametilenopropiónico, que contribui para suas propriedades únicas. Este composto exibe forte afinidade pelos receptores de vasopressina, influenciando a função renal e o tônus vascular. Além disso, a vasotocina está envolvida em comportamentos sociais e respostas ao estresse em certas espécies. Seu número CAS, 114056-26-7, a identifica de maneira única em bancos de dados químicos, facilitando a pesquisa e aplicação em farmacologia e bioquímica. A presença de resíduos específicos de aminoácidos, como O-metil-Tyr e Orn, indica potencial para interações variadas dentro dos sistemas biológicos, tornando-a um tema de interesse em estudos relacionados à neuroendocrinologia e ao desenvolvimento terapêutico. No geral, as características da vasotocina ressaltam sua importância nas ciências biológicas básicas e aplicadas.

Fórmula: C₅₄H₇₉N₁₁O₁₃S₂

InChI: InChI=1/C54H79N11O13S2/c1-5-30(2)44(63-49(73)38(26-32-13-17-34(67)18-14-32)58-43(69)28-54(80)21-7-6-8-22-54)51(75)64-45(31(3)66)52(76)61-39(27-42(56)68)48(72)62-40(29-79)53(77)65-24-10-12-41(65)50(74)59-36(11-9-23-55)47(71)60-37(46(57)70)25-33-15-19-35(78-4)20-16-33/h13-20,29-31,36-41,44-45,66-67,80H,5-12,21-28,55H2,1-4H3,(H2,56,68)(H2,57,70)(H,58,69)(H,59,74)(H,60,71)(H,61,76)(H,62,72)(H,63,73)(H,64,75)/t30-,31+,36-,37-,38-,39-,40-,41-,44-,45-/m0/s1

Sinónimos:

• 1-d(CH2)5-2-(O-Methyl)-tyrosyl-4-theonyl-8-ornithyl-9-tyrosinamide-vasotocin
• N-((1-Mercaptocyclohexyl)acetyl)-O-methyl-L-tyrosyl-L-isoleucyl-L-threonyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-ornithyl-L-tyrosinamide cyclic (1-5)-disulfide
• Ovta
• Ota-vasotocin
• d(CH2)5-O-Methyl-tyrosyl(2)-threonyl(4)-ornithyl(8)-tyrosinamide(9)-vasotocin
• d(CH2)5-Tyr(Me)(2)-thr(4)-orn(8)-tyr(9)-NH2-vasotocin
• L-Tyrosinamide, N-((1-mercaptocyclohexyl)acetyl)-O-methyl-L-tyrosyl-L-isoleucyl-L-threonyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-ornithyl-, cyclic (1-5)-disulfide
• N-[(1-sulfanylcyclohexyl)acetyl]-L-tyrosyl-L-isoleucyl-L-threonyl-L-asparaginyl-3-thioxo-L-alanyl-L-prolyl-L-ornithyl-O-methyl-L-tyrosinamide
• Vasotocin, (beta-mercapto-beta,beta-cyclopentamethylenepropionic acid)-O-methyl-tyr(2)-thr(4)-orn(8)-tyr(9)-NH2
• b-Mercapto-b,b-cyclopentaMethylene-propionyl-Tyr(Me)-Ile-Thr-Asn-Cys-Pro-Orn-Tyr-NH2
• (2S)-N-[(2R)-1-[(2S)-2-[[(2S)-5-amino-1-[[(2S)-1-amino-3-(4-methoxyphenyl)-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxo-3-sulfanylidenepropan-2-yl]-2-[[(2S,3R)-3-hydroxy-2-[[(2S,3S)-2-[[(2S)-3-(4-hydroxyphenyl)-2-[[2-(1-sulfanylcyclohexyl)acetyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]butanoyl]amino]butanediamide
• (2S)-N-[(2R)-1-[(2S)-2-[[(2S)-5-amino-1-[[(2S)-1-amino-3-(4-methoxyphenyl)-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxo-3-sulfanylidenepropan-2-yl]-2-[[(2S,3R)-3-hydroxy-2-[[(2S,3S)-2-[[(2S)-3-(4-hydroxyphenyl)-2-[[2-(1-sulfan

(d(CH₂)₅¹,Tyr(Me)²,Thr⁴,Orn⁸,Tyr-NH₂⁹)-Vasotocin

CAS: 114056-26-7

The oxytocin antagonist OVTA shows enhanced affinity for rat uterine oxytocin receptors after iodination.

Fórmula: C₅₄H₇₉N₁₁O₁₃S₂

Pureza: 98.7%

Cor e Forma: White Powder

Peso molecular: 1154.42

Ref: 01-4015938

Ota-vasotocin

CAS: 114056-26-7

Ota-vasotocin is a ligand utilized in quantitative receptor autoradiography for oxytocin receptors.

Fórmula: C₅₄H₇₉N₁₁O₁₃S₂

Peso molecular: 1154.41

Ref: TM-T25902

(d(CH2)51,Tyr(Me)2,Thr4, Orn 8,Tyr-NH29)-Vasotocin trifluoroacetate salt

CAS: 114056-26-7

Vasotocin is a peptide that belongs to the family of arginine vasotocin and oxytocin receptor antagonists. It is synthesized in the rat kidney, where it is stored in vesicles. Vasotocin has been shown to bind to the oxytocin receptor, which regulates many physiological processes such as muscle contraction, ejaculation, and milk letdown. Vasotocin also modulates the activity of antigen-presenting cells and can be used for pharmaceutical formulations. This drug has been shown to be effective against congestive heart failure and may be used as a diluent for other drugs.br>br>
Vasotocin trifluoroacetate salt (VT) is an oxime derivative that can be isolated from vasotocin. The synthesis of VT involves converting vasotocin into its trifluoroacetate salt by adding trifluoroacetic acid, followed by reacting with hydroxylam

Fórmula: C₅₄H₇₉N₁₁O₁₃S₂

Pureza: Min. 95%

Peso molecular: 1,154.4 g/mol

Ref: 3D-FT110427