CAS 1142-20-7
:Benzyloxi-carbonil-L-alanina
Descrição:
Benzyloxi-carbonil-L-alanina, comumente referido como Z-L-alanina, é um derivado do aminoácido alanina onde o grupo amino é protegido por um grupo benzyloxycarbonilo (Z). Este composto é caracterizado por sua aparência cristalina branca e é solúvel em solventes orgânicos como metanol e dimetilsulfóxido, mas tem solubilidade limitada em água. O grupo Z serve como um grupo protetor na síntese de peptídeos, permitindo reações seletivas sem interferir nos grupos funcionais do aminoácido. O composto tem uma fórmula molecular que reflete sua estrutura, incorporando tanto a espinha dorsal da alanina quanto a parte benzyloxycarbonilo. Sua estabilidade sob condições laboratoriais padrão o torna um intermediário valioso na síntese orgânica e na química de peptídeos. Além disso, a Z-L-alanina é frequentemente utilizada na preparação de vários peptídeos e pode estar envolvida no estudo da estrutura e função das proteínas devido ao seu papel na modificação de sequências de aminoácidos. Os dados de segurança indicam que, como muitas substâncias químicas, deve ser manuseada com cuidado, seguindo os protocolos de segurança apropriados.
Fórmula:C11H13NO4
InChI:InChI=1S/C11H13NO4/c1-8(10(13)14)12-11(15)16-7-9-5-3-2-4-6-9/h2-6,8H,7H2,1H3,(H,12,15)(H,13,14)/t8-/m0/s1
Chave InChI:InChIKey=TYRGLVWXHJRKMT-QMMMGPOBSA-N
SMILES:C(OC(N[C@H](C(O)=O)C)=O)C1=CC=CC=C1
Sinónimos:- (2S)-2-[[(Benzyloxy)carbonyl]amino]propanoic acid
- (S)-2-(Benzyloxycarbonylamino)propanoic acid
- (S)-2-[(Benzyloxycarbonyl)amino]propionic acid
- <span class="text-smallcaps">L</span>-Alanine, N-[(phenylmethoxy)carbonyl]-
- <span class="text-smallcaps">L</span>-Alanine, N-carboxy-, N-benzyl ester
- <span class="text-smallcaps">L</span>-Carbobenzoxyalanine
- <span class="text-smallcaps">L</span>-Carbobenzyloxyalanine
- <span class="text-smallcaps">L</span>-Cbz alanine
- <span class="text-smallcaps">L</span>-N-(Benzyloxycarbonyl)alanine
- Alanine, N-carboxy-, N-benzyl ester, <span class="text-smallcaps">L</span>-
- Alanine, N-carboxy-, N-benzyl ester, L-
- Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-alanine
- Benzyloxycarbonyl-L-alanine
- Cbz-<span class="text-smallcaps">L</span>-Ala-OH
- L-Alanine, N-carboxy-, N-benzyl ester
- L-Carbobenzoxyalanine
- L-Carbobenzyloxyalanine
- L-N-(Benzyloxycarbonyl)alanine
- N-(Benzyloxycarbonyl)-(S)-alanine
- N-(Carbobenzoxy)-<span class="text-smallcaps">L</span>-alanine
- N-(Carbobenzoxy)-L-alanine
- N-Benzoxycarbonyl-<span class="text-smallcaps">L</span>-alanine
- N-Benzoxycarbonyl-L-alanine
- N-Benzyloxycarbonyl-L-alanin
- N-Carbobenzyloxy-<span class="text-smallcaps">L</span>-alanine
- N-Carbobenzyloxy-L-alanine
- N-Cbz alanine
- N-[(Benzyloxy)carbonyl]-<span class="text-smallcaps">L</span>-alanine
- N-[(Benzyloxy)carbonyl]-L-alanine
- N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-alanine
- N-[(Phenylmethoxy)carbonyl]-L-alanine
- N-benciloxicarbonil-L-alanina
- N-benzyloxycarbonyl-L-alanine
- Nsc 156978
- Nsc 88469
- z-Ala
- N-CBZ-L-Alanine
- (2S)-2-{[(benzyloxy)carbonyl]amino}propanoate
- Cbz-Ala-OH
- Z-L-Alanine
- Z-Ala-OH
- N-Cbz-L-Ala-OH
- N-[(benzyloxy)carbonyl]-D-alanine
- Cbz-L-alanine
- BenzyloxycarbonylLalanine
- Ver mais sinónimos
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12 produtos.
N-Carbobenzoxy-L-alanine
CAS:Fórmula:C11H13NO4Pureza:>99.0%(T)(HPLC)Cor e Forma:White to Almost white powder to crystalPeso molecular:223.23N-Benzyloxycarbonyl-L-alanine, 98%
CAS:<p>This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci</p>Fórmula:C11H13NO4Pureza:98%Cor e Forma:crystalline powder, WhitePeso molecular:223.23Z-Ala-OH
CAS:<p>Bachem ID: 4000246.</p>Fórmula:C11H13NO4Pureza:99.4%Cor e Forma:White PowderPeso molecular:223.23L-Alanine, N-CBZ protected
CAS:L-Alanine, N-CBZ protectedFórmula:C11H13NO4Pureza:97%Cor e Forma: white solidPeso molecular:223.22522g/molZ-Ala-OH
CAS:<p>M03069 - Z-Ala-OH</p>Fórmula:C11H13NO4Pureza:97%Cor e Forma:Solid, White powderPeso molecular:223.228N-Benzyloxycarbonyl-L-alanine
CAS:Produto Controlado<p>Applications N-Benzyloxycarbonyl-L-alanine is an intermediate in the synthesis of Perindopril (P287500), an angiotensin-converting enzyme (ACE) inhibitor. Antihypertensive.<br>References Lees, K.R., et al.: Brit. J. Clin. Pharmacol., 23, 159 (1987); Morgan, T., et al.: J. Cardiovasc. Pharmacol., 10, Supp. 7, S116, (1987)<br></p>Fórmula:C11H13NO4Cor e Forma:NeatPeso molecular:223.23Z-L-Alanine extrapure, 99%
CAS:Fórmula:C11H13NO4Pureza:min. 99%Cor e Forma:White, Crystalline powder, Clear, ColourlessPeso molecular:223.21Z-L-Alanine
CAS:Z-L-Alanine is a cytosolic enzyme inhibitor that inhibits the activity of enzymes involved in protein catalysis. This inhibition is stereoselective, with the L-enantiomer having the stronger inhibitory effect. Z-L-Alanine has been shown to be an effective inhibitor of proteolytic enzymes and has been used as an additive in buffers to prevent enzymatic degradation. Molecular modeling studies have demonstrated that Z-L-Alanine can bind to the active site of these enzymes and inhibit their activity by binding to the catalytic triad of serine, aspartate, and histidine residues. The molecular structure of Z-L-Alanine resembles that of a natural substrate for these enzymes, which may account for its effectiveness in inhibiting them. FTIR spectroscopy has confirmed the presence of Z-L-alanine in a sample obtained from a bacterial culture. Liquid chromatography has shown that this amino acid is present at high levels in variousFórmula:C11H13NO4Pureza:Min. 95%Cor e Forma:White Off-White PowderPeso molecular:223.23 g/mol
