CAS 1145-80-8

N-(Benzyloxi-carbonil)-L-serina

Descrição:

N-(Benzyloxi-carbonil)-L-serina, também conhecido como Z-L-serina, é um derivado do aminoácido L-serina, caracterizado pela presença de um grupo protetor benzyloxycarbonilo (Z) no grupo amino. Este composto é tipicamente um sólido cristalino branco a off-white e é solúvel em solventes orgânicos polares, como metanol e dimetilsulfóxido, mas menos solúvel em solventes não polares. É comumente utilizado na síntese de peptídeos como um grupo protetor para o grupo amino, permitindo reações seletivas no grupo carboxila ou nas cadeias laterais. O grupo Z pode ser removido em condições ácidas suaves, facilitando a desproteção do grupo amino quando necessário. N-(Benzyloxi-carbonil)-L-serina também é de interesse na pesquisa bioquímica e em aplicações farmacêuticas devido ao seu papel na síntese de peptídeos e proteínas. Sua estrutura molecular inclui um centro quiral, tornando-o opticamente ativo, e exibe propriedades típicas dos aminoácidos, como a capacidade de participar em ligações de hidrogênio e formar espécies zwitteriônicas em solução.

Fórmula: C₁₁H₁₃NO₅

InChI: InChI=1S/C11H13NO5/c13-6-9(10(14)15)12-11(16)17-7-8-4-2-1-3-5-8/h1-5,9,13H,6-7H2,(H,12,16)(H,14,15)/t9-/m0/s1

Chave InChI: InChIKey=GNIDSOFZAKMQAO-VIFPVBQESA-N

SMILES: C(OC(N[C@H](C(O)=O)CO)=O)C1=CC=CC=C1

Sinónimos:

• (2S)-2-[(Benzyloxycarbonyl)amino]-3-hydroxypropanoic acid
• (2S)-2-[[(Benzyloxy)carbonyl]amino]-3-hydroxypropanoic acid
• (2S)-3-Hydroxy-2-(phenylmethoxycarbonylamino)propanoic acid
• (S)-2-(Benzyloxycarbonylamino)-3-hydroxypropanoic acid
• <span class="text-smallcaps">L</span>-Carbobenzyloxy serine
• <span class="text-smallcaps">L</span>-Serine, N-[(phenylmethoxy)carbonyl]-
• <span class="text-smallcaps">L</span>-Serine, N-carboxy-, N-benzyl ester
• Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-serine
• Cbz-L-serine
• N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-serine
• N-Benzyloxycarbonyl-L-serine
• N-Carbobenzoxy-<span class="text-smallcaps">L</span>-serine
• N-Carbobenzyloxy-<span class="text-smallcaps">L</span>-serine
• N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-serine
• N-[(Phenylmethoxy)carbonyl]serine
• N-[(benzyloxy)carbonyl]-L-serine
• N-[(benzyloxy)carbonyl]serine
• N-cbz-l-serine
• NSC 286604
• Serine, N-carboxy-, N-benzyl ester, <span class="text-smallcaps">L</span>-
• Z-Ser-OH
• L-Serine, N-[(phenylmethoxy)carbonyl]-
• L-Serine, N-carboxy-, N-benzyl ester
• N-[(Phenylmethoxy)carbonyl]-L-serine

N-Benzyloxycarbonyl-L-serine

CAS: 1145-80-8

Fórmula: C₁₁H₁₃NO₅

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 239.23

Ref: 3B-C0635

N-Benzyloxycarbonyl-L-serine, 99%

CAS: 1145-80-8

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₁₁H₁₃NO₅

Pureza: 99%

Cor e Forma: Powder, White

Peso molecular: 239.23

Ref: 02-A19050

Z-Ser-OH

CAS: 1145-80-8

Educt in Hoveyda’s synthesis of L-3-fluoroalanine and N-methyl-L-3-fluoroalanine derivatives via the oxazolidinone.

Fórmula: C₁₁H₁₃NO₅

Pureza: > 99%

Cor e Forma: White

Peso molecular: 239.23

Ref: 01-4001465

L-Serine, N-[(phenylmethoxy)carbonyl]-

CAS: 1145-80-8

Fórmula: C₁₁H₁₃NO₅

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 239.2246

Ref: IN-DA000EKT

Z-Ser-OH

CAS: 1145-80-8

Fórmula: C₁₁H₁₃NO₅

Peso molecular: 239.23

Ref: 7W-GM2492

Carbobenzyloxy-l-serine

CAS: 1145-80-8

Carbobenzyloxy-l-serine

Pureza: 98%

Peso molecular: 239.22g/mol

Ref: 54-OR322046

Z-L-Serine extrapure, 99%

CAS: 1145-80-8

Fórmula: C₁₁H₁₃NO₅

Pureza: min. 99%

Cor e Forma: White to Cream powder, Crystalline powder

Peso molecular: 239.2

Ref: SR-75675

Z-Ser-OH

CAS: 1145-80-8

M03053 - Z-Ser-OH

Fórmula: C₁₁H₁₃NO₅

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 239.227

Ref: 10-M03053

N-Carboxybenzyl-L-serine-13C3

Produto Controlado

CAS: 1145-80-8

Applications is an intermediate used in the synthesis of L-3-Phosphoglyceric Acid 13C3 (P358007), which is carbon-13 labelled L-3-Phosphoglyceric Acid. 3-Phosphoglyceric acid is involved in glutamate biosynthesis in syntrophus aciditrophicus. 3-Phosphoglyceric acid can also be used to study pyruvate carboxylation in SDH-deficient kidney mouse cells.
References Kim, M., et al.: Appl. Environ. Microbiol. 81, 8434 (2015); Cardaci, S., et al.: Nat. Cell. Biol. 17, 1317 (2015)

Fórmula: C₃C₈H₁₃NO₅

Cor e Forma: Neat

Peso molecular: 242.20258

Ref: TR-C182416

N-Carboxybenzyl-L-serine

Produto Controlado

CAS: 1145-80-8

Applications Building block in peptide synthesis.
References Pansare, S. V.; Org. Synth. 70, 10(1992)

Fórmula: C₁₁H₁₃NO₅

Cor e Forma: Neat

Peso molecular: 239.22

Ref: TR-C182415

N-Cbz-L-serine

CAS: 1145-80-8

N-Cbz-L-serine is a synthetic amino acid that has been shown to have antimicrobial effects. It has been found to inhibit the growth of bacteria, fungi, and protozoa by inhibiting their cell membranes. This amino acid also inhibits the synthesis of phospholipids in bacterial cell walls and may be used as an antimicrobial agent for industrial applications. N-Cbz-L-serine contains both a hydroxy group and a hydroxyl group, which are essential for its antibacterial activity. The fatty acids present in this compound can be either saturated or unsaturated. Multigram quantities of N-Cbz-L-serine have been produced with high purity using asymmetric synthesis methods.

Fórmula: C₁₁H₁₃NO₅

Pureza: Min. 95%

Cor e Forma: White/Off-White Solid

Peso molecular: 239.22 g/mol

Ref: 3D-FC19786