CAS 114748-71-9

N-[3-[4-Amino-7-[(2R,5S)-tetraidro-5-(hidroximetil)-2-furanil]-7H-pirrolo[2,3-d]pirimidin-5-il]-2-propin-1-il]-2,2,2-trifluoroacetamida

Descrição:

N-[3-[4-Amino-7-[(2R,5S)-tetraidro-5-(hidroximetil)-2-furanil]-7H-pirrolo[2,3-d]pirimidin-5-il]-2-propin-1-il]-2,2,2-trifluoroacetamida, com número CAS 114748-71-9, é um composto orgânico complexo caracterizado por suas características estruturais únicas, incluindo um núcleo de pirrolo[2,3-d]pirimidina e um grupo funcional trifluoroacetamida. Este composto exibe propriedades típicas de compostos heterocíclicos, como potencial atividade biológica devido à presença de grupos amino e hidroximetila, que podem aumentar sua solubilidade e reatividade. O grupo trifluoroacetamida contribui para sua estabilidade e pode influenciar sua interação com alvos biológicos. A estereoquímica indicada pela configuração (2R,5S) sugere arranjos espaciais específicos que podem afetar as propriedades farmacológicas do composto. No geral, esta substância pode ser de interesse na química medicinal, particularmente no desenvolvimento de fármacos direcionados a vias biológicas específicas. Estudos adicionais seriam necessários para elucidar seu espectro completo de características, incluindo sua solubilidade, estabilidade e atividade biológica.

Fórmula: C₁₆H₁₆F₃N₅O₃

InChI: InChI=1S/C16H16F3N5O3/c17-16(18,19)15(26)21-5-1-2-9-6-24(11-4-3-10(7-25)27-11)14-12(9)13(20)22-8-23-14/h6,8,10-11,25H,3-5,7H2,(H,21,26)(H2,20,22,23)/t10-,11+/m0/s1

Chave InChI: InChIKey=WUXCPWCITSUNMX-WDEREUQCSA-N

SMILES: C(#CCNC(C(F)(F)F)=O)C=1C=2C(N(C1)[C@@H]3O[C@H](CO)CC3)=NC=NC2N

Sinónimos:

• Acetamide, N-[3-[4-amino-7-[tetrahydro-5-(hydroxymethyl)-2-furanyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-propynyl]-2,2,2-trifluoro-, (2R-cis)-
• 7H-Pyrrolo[2,3-d]pyrimidine, acetamide deriv.
• Acetamide, N-[3-[4-amino-7-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-propyn-1-yl]-2,2,2-trifluoro-
• N-[3-[4-Amino-7-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-propyn-1-yl]-2,2,2-trifluoroacetamide

N-[3-[4-Amino-7-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-propyn-1-yl]-2,2,2-trifluoroacetamide

CAS: 114748-71-9

Fórmula: C₁₆H₁₆F₃N₅O₃

Peso molecular: 383.3251

Ref: IN-DA000F5L

7-TFA-ap-7-Deaza-ddA

CAS: 114748-71-9

Compound 19c is a nucleotide derivative for DNA sequencing dye terminators.

Fórmula: C₁₆H₁₆F₃N₅O₃

Cor e Forma: Solid

Peso molecular: 383.331

Ref: TM-T38534

7-Deazaadenosine- 2', 3'- dideoxy- 7[3- (trifluoroacetyl) amino] - 1- propyn- yl

CAS: 114748-71-9

7-Deazaadenosine is a synthetic nucleoside that is used as an antiviral and antitumor agent. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. 7-Deazaadenosine also has antiviral activity, inhibiting viral DNA synthesis by interfering with the enzyme DNA polymerase. 7-Deazaadenosine has been shown to be more potent than other deoxyribonucleosides against various HIV strains, including HIV-1 group M and HIV-1 group O. This drug was originally developed for use as a chemotherapeutic agent but has since been used as a research reagent for studying the mechanism of action of various drugs on DNA.

Fórmula: C₁₆H₁₆F₃N₅O₃

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 383.33 g/mol

Ref: 3D-ND156888

7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine

CAS: 114748-71-9

7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine is a diphosphate nucleoside analogue that can be activated by phosphoramidites. It is a novel, synthetic, and high quality nucleotide with antiviral and anticancer properties. This drug has been shown to inhibit the synthesis of DNA and RNA at the transcriptional level. 7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine is a monophosphate nucleoside analogue that can be used in ribonucleotide synthesis for the treatment of cancer.

Fórmula: C₁₆H₁₆F₃N₅O₃

Peso molecular: 383.33 g/mol

Ref: 3D-J-700297