CAS 1148-11-4

Benzyloxi-carbonil-L-prolina

Descrição:

Benzyloxi-carbonil-L-prolina, comumente referido como Z-Prolina, é um derivado do aminoácido prolina, caracterizado pela presença de um grupo protetor benzyloxycarbonilo (Z). Este composto é tipicamente utilizado na síntese de peptídeos como um grupo protetor para a funcionalidade amino da prolina, o que ajuda a prevenir reações indesejadas durante o processo de síntese. A Z-Prolina é um sólido cristalino branco a branco sujo que é solúvel em solventes orgânicos como metanol e dimetilsulfóxido, mas tem solubilidade limitada em água. Sua estrutura molecular inclui uma espinha dorsal de prolina, que contribui para suas propriedades conformacionais únicas, tornando-a valiosa no design de peptídeos e proteínas. O composto é estável em condições normais de laboratório, mas pode sofrer hidrólise ou desproteção em condições ácidas ou básicas. Devido ao seu papel na química de peptídeos, a Z-Prolina é significativa na pesquisa farmacêutica e no desenvolvimento de compostos biologicamente ativos. Os dados de segurança devem ser consultados para manuseio, assim como com qualquer substância química.

Fórmula: C₁₃H₁₅NO₄

InChI: InChI=1S/C13H15NO4/c15-12(16)11-7-4-8-14(11)13(17)18-9-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H,15,16)/t11-/m0/s1

Chave InChI: InChIKey=JXGVXCZADZNAMJ-NSHDSACASA-N

SMILES: C(OCC1=CC=CC=C1)(=O)N2[C@H](C(O)=O)CCC2

Sinónimos:

• (2S)-1,2-Pyrrolidinedicarboxylic acid 1-(phenylmethyl) ester
• (2S)-1-(Benzyloxycarbonyl)pyrrolidine-2-carboxylic acid
• (2S)-1-Phenylmethoxycarbonylpyrrolidine-2-carboxylic acid
• (2S)-1-[(benzyloxy)carbonyl]pyrrolidine-2-carboxylate
• (S)-1-(Benzyloxycarbonyl)pyrrolidine-2-carboxylic acid
• 1,2-Pyrrolidinedicarboxylic acid, 1-(phenylmethyl) ester, (2S)-
• 1,2-Pyrrolidinedicarboxylic acid, 1-(phenylmethyl) ester, (S)-
• 1,2-Pyrrolidinedicarboxylic acid, 1-benzyl ester, <span class="text-smallcaps">L</span>-
• 1,2-Pyrrolidinedicarboxylic acid, 1-benzyl ester, L-
• 1-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-proline
• 1-(Benzyloxycarbonyl)-L-proline
• 1-Carbobenzoxy-<span class="text-smallcaps">L</span>-proline
• 1-Carbobenzoxy-L-proline
• 1-[(Benzyloxy)Carbonyl]Proline
• 1-[(benzyloxy)carbonyl]-D-proline
• 1-[(benzyloxy)carbonyl]-L-proline
• <span class="text-smallcaps">L</span>-Cbz-Proline
• Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-proline
• Benzyloxycarbonyl-L-proline
• Carbobenzoxy-<span class="text-smallcaps">L</span>-proline
• Carbobenzoxy-L-proline
• Carbobenzoxy-S-proline
• Carbobenzyloxy-<span class="text-smallcaps">L</span>-proline
• Carbobenzyloxy-L-proline
• Cbz-<span class="text-smallcaps">L</span>-Pro-OH
• Cbz-L-Pro-OH
• Cbz-L-proline
• N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-proline
• N-(Carbobenzyloxy)-<span class="text-smallcaps">L</span>-proline
• N-Benzyloxycarbonyl-(S)-proline
• N-Benzyloxycarbonyl-L-prolin
• N-Benzyloxycarbonyl-L-proline
• N-CBZ-L-Proline N-Carbobenzyloxy-L-proline
• N-Carbobenzoxy-<span class="text-smallcaps">L</span>-proline
• N-Carbobenzoxy-L-proline
• N-Carbobenzyloxy-(S)-proline
• N-Cbz-<span class="text-smallcaps">L</span>-proline
• N-Cbz-L-Pro-OH
• N-Cbz-L-proline
• N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-proline
• N-[(Phenylmethoxy)carbonyl]-L-proline
• N-benciloxicarbonil-L-prolina
• N-cbz-L-proline crystalline
• Z-L-Proline
• Z-Pro-OH
• N-CARBOBENZYLOXY-L-PROLINE
• N-ALPHA-BENZYLOXYCARBONYL-L-PROLINE
• N-ALPHA-CBZ-L-PROLINE
• (2S)-1-[(BENZYLOXY)CARBONYL]PYRROLIDINE-2-CARBOXYLIC ACID
• CBZ-PRO-OH
• N-ALPHA-CARBOBENZOXY-L-PROLINE
• (S)-N-CBZ-PYRROLIDINE-2-CARBOXYLIC ACID
• N-CBZ-L-PROLINE-OH
• Z-L-PRO-OH
• N-ALPHA-CARBOBENZOXY-L-PYRROLIDINE-2-CARBOXYLIC ACID
• L-CBZ-PROLINE

N-Benzyloxycarbonyl-L-proline

CAS: 1148-11-4

Fórmula: C₁₃H₁₅NO₄

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 249.27

Ref: 3B-C0713

N-Benzyloxycarbonyl-L-proline, 98+%

CAS: 1148-11-4

N-(Benzyloxycarbonyl)-L-proline is a potent inhibitor of prolidase; a specific peptidase that cleaves dipeptides with a C-terminal prolyl and hydroxylprolyl residue. It is also used in the synthesis of N-(L-Prolyl)--alanine which is a derivative of the naturally occurring beta amino acid -Alanine. T

Fórmula: C₁₃H₁₄NO₄

Pureza: 98+%

Cor e Forma: Powder or crystalline powder or crystals or granules, White to cream

Peso molecular: 248.26

Ref: 02-B21672

Z-Pro-OH

CAS: 1148-11-4

Bachem ID: 4001343.

Fórmula: C₁₃H₁₅NO₄

Pureza: 99.1%

Cor e Forma: White

Peso molecular: 249.27

Ref: 01-4001343

Z-Pro-OH

CAS: 1148-11-4

Fórmula: C₁₃H₁₅NO₄

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 249.2625

Ref: IN-DA007RF9

(2S)-Pyrrolidine-2-carboxylic acid, N-CBZ protected

CAS: 1148-11-4

(2S)-Pyrrolidine-2-carboxylic acid, N-CBZ protected

Fórmula: C₁₃H₁₅NO₄

Pureza: 98%

Cor e Forma: white solid

Peso molecular: 249.26g/mol

Ref: 54-OR61280

Carbobenzoxyproline

CAS: 1148-11-4

Carbobenzoxyproline

Pureza: ≥98%

Peso molecular: 249.26g/mol

Ref: 54-BUP19312

Z-Pro-OH

CAS: 1148-11-4

Fórmula: C₁₃H₁₅NO₄

Peso molecular: 249.27

Ref: 7W-GM1976

Carbobenzoxyproline

CAS: 1148-11-4

Carbobenzoxyproline (Carbobenzoxy-S-proline) is a prolidase inhibitor.

Fórmula: C₁₃H₁₅NO₄

Pureza: 99.79%

Cor e Forma: White To Light Yellow Crystal Powder

Peso molecular: 249.26

Ref: TM-T20125

Z-Pro-OH

CAS: 1148-11-4

M03066 - Z-Pro-OH

Fórmula: C₁₃H₁₅NO₄

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 249.266

Ref: 10-M03066

N-Benzyloxycarbonyl-L-proline

CAS: 1148-11-4

N-Benzyloxycarbonyl-L-proline is a cationic polymerization inhibitor that has been shown to inhibit the growth of Pseudomonas aeruginosa. It inhibits bacterial growth by inhibiting the production of collagen, an important component in the cell wall. N-Benzyloxycarbonyl-L-proline is also used as a histological staining agent and has been shown to be effective against breast cancer cells resistant to tamoxifen therapy.

Fórmula: C₁₃H₁₅NO₄

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 249.26 g/mol

Ref: 3D-FB37965

Z-L-Proline extrapure, 99%

CAS: 1148-11-4

Fórmula: C₁₃H₁₅NO₄

Pureza: min. 99%

Cor e Forma: White, Crystalline powder

Peso molecular: 249.3

Ref: SR-31688

N-(Benzyloxycarbonyl)-L-proline

Produto Controlado

CAS: 1148-11-4

Applications N-(Benzyloxycarbonyl)-L-proline is a potent in vitro and in vivo inhibitor of prolidase; a specific peptidase that cleaves dipeptides with a C-terminal prolyl and hydroxylprolyl residue. N-(Benzyloxycarbonyl)-L-proline is also used in the synthesis of N-(L-Prolyl)-β-alanine (P756190) which is a derivative of the naturally occurring beta amino acid β-Alanine (A637320).
References Lupi, A., et al.: BBA-Mol. Cell Res., 1744, 157 (2005)

Fórmula: C₁₃H₁₅NO₄

Cor e Forma: Neat

Peso molecular: 249.26

Ref: TR-B287810

Acalabrutinib Impurity 18

CAS: 1148-11-4

Fórmula: C₁₃H₁₅NO₄

Peso molecular: 249.27

Ref: ST-EA-CP-A165007