CAS 1161925-41-2

NVP-BQS481

CAS: 1161925-41-2

NVP-BQS481 (Compound 1) is a selective inhibitor of spindle motor protein 5 (Eg5), with an IC50 of less than 0.5 nM. It demonstrates significant anti-mitotic and anti-tumor activities, exhibiting an IC50 of 0.09 nM against SK-OV-3ip cells. NVP-BQS481 is suitable for use as a cytotoxic payload in the synthesis of antibody-drug conjugates (ADCs).

Fórmula: C₂₇H₃₃F₃N₄O₂

Cor e Forma: Solid

Peso molecular: 502.57

Ref: TM-T212559