CAS 1164-16-5

Carbobenzoxi-L-tirosina

Descrição:

Carbobenzoxi-L-tirosina, também conhecido como Z-Tyr-OH, é um derivado do aminoácido tirosina, onde o grupo amino é protegido por um grupo carbobenzóico (Z). Este composto é caracterizado por sua aparência cristalina branca a off-white e é solúvel em solventes orgânicos como metanol e dimetilsulfóxido, mas tem solubilidade limitada em água. É comumente utilizado na síntese de peptídeos como um grupo protetor para a funcionalidade amino da tirosina, permitindo reações seletivas sem interferência do grupo amino. O grupo Z pode ser removido sob condições específicas, facilitando a formação subsequente de peptídeos. Carbobenzoxi-L-tirosina também é utilizado em várias aplicações bioquímicas, incluindo estudos de atividade enzimática e interações proteicas. Sua estabilidade e reatividade fazem dele um intermediário valioso na síntese orgânica e no desenvolvimento farmacêutico. Assim como muitas substâncias químicas, devem ser observadas as precauções adequadas de manuseio e segurança devido aos perigos potenciais associados ao seu uso.

Fórmula: C₁₇H₁₇NO₅

InChI: InChI=1S/C17H17NO5/c19-14-8-6-12(7-9-14)10-15(16(20)21)18-17(22)23-11-13-4-2-1-3-5-13/h1-9,15,19H,10-11H2,(H,18,22)(H,20,21)/t15-/m0/s1

Chave InChI: InChIKey=MCRMUCXATQAAMN-HNNXBMFYSA-N

SMILES: C([C@H](NC(OCC1=CC=CC=C1)=O)C(O)=O)C2=CC=C(O)C=C2

Sinónimos:

• (2S)-2-(Benzyloxycarbonylamino)-3-(4-hydroxyphenyl)propanoic acid
• (2S)-2-[[(Benzyloxy)carbonyl]amino]-3-(4-hydroxyphenyl)propanoic acid
• (2S)-2-{[(benzyloxy)carbonyl]amino}-3-(4-hydroxyphenyl)propanoate
• (2S)-3-(4-Hydroxyphenyl)-2-(phenylmethoxycarbonylamino)propanoic acid
• (Benzyloxycarbonyl)tyrosine
• 2-{[(Benzyloxy)carbonyl]amino}-3-(4-hydroxyphenyl)propanoic acid
• <span class="text-smallcaps">L</span>-(Carbobenzyloxy)tyrosine
• <span class="text-smallcaps">L</span>-Tyrosine, N-[(phenylmethoxy)carbonyl]-
• Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-tyrosine
• BenzyloxycarbonylLtyrosine
• CBZ-L-Tyrosine-OH
• Carbobenzoxy-<span class="text-smallcaps">L</span>-tyrosine
• Carbobenzoxytyrosine
• Cbz-L-tyrosine
• N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-tyrosine
• N-(Benzyloxycarbonyl)tyrosine
• N-Benzyloxycarbonyl-L-tyrosine~Z-Tyr-OH
• N-CBZ-<span class="text-smallcaps">L</span>-tyrosine
• N-CBZ-L-Tyrosine N-Carbobenzyloxy-L-tyrosine
• N-Carbobenzoxy-<span class="text-smallcaps">L</span>-tyrosine
• N-Carbobenzoxytyrosine
• N-Carbobenzyloxy-<span class="text-smallcaps">L</span>-tyrosine
• N-Carbobenzyloxy-L-tyrosine dihydrate
• N-Cbz-L-tyrosine
• N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-tyrosine
• N-[(benzyloxy)carbonyl]tyrosine
• N-cbz-L-tyrosine crystalline
• NSC 88488
• Na-Benzyloxycarbonyl-L-tyrosine
• Tyrosine, N-carboxy-, N-benzyl ester
• Tyrosine, N-carboxy-, N-benzyl ester, <span class="text-smallcaps">L</span>-
• Z-L-Tyr
• Z-L-tyrosine dihydrate
• Z-L-tyrosine hydrate
• Z-Tyr-OH hydrate
• Z-Tyr-Oh
• Tyrosine, N-carboxy-, N-benzyl ester, L-
• L-Tyrosine, N-[(phenylmethoxy)carbonyl]-
• N-[(Phenylmethoxy)carbonyl]-L-tyrosine

N-Benzyloxycarbonyl-L-tyrosine, 99%, may contain up to ca 10% water

CAS: 1164-16-5

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Fórmula: C₁₇H₁₇NO₅

Pureza: 99%

Cor e Forma: White to pale cream, Powder

Peso molecular: 315.33

Ref: 02-A10966

Z-Tyr-OH

CAS: 1164-16-5

Bachem ID: 4001149.

Fórmula: C₁₇H₁₇NO₅

Pureza: 99.68%

Cor e Forma: Whitish

Peso molecular: 315.33

Ref: 01-4001149

L-Tyrosine, N-[(phenylmethoxy)carbonyl]-

CAS: 1164-16-5

Fórmula: C₁₇H₁₇NO₅

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 315.3206

Ref: IN-DA000CER

Z-Tyr-OH

CAS: 1164-16-5

Fórmula: C₁₇H₁₇NO₅

Peso molecular: 315.33

Ref: 7W-GM1261

L-Tyrosine, N-CBZ protected

CAS: 1164-16-5

L-Tyrosine, N-CBZ protected

Pureza: 98%

Peso molecular: 315.32g/mol

Ref: 54-OR0222

N-Benzyloxycarbonyl-L-tyrosine

CAS: 1164-16-5

Fórmula: C₁₇H₁₇NO₅

Pureza: >98.0%(T)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 315.33

Ref: 3B-C1729

z-tyr-oh

CAS: 1164-16-5

Fórmula: C₁₇H₁₇NO₅

Pureza: 98%

Cor e Forma: Beige powder

Peso molecular: 315.325

Ref: 10-F045507

N-Cbz-L-tyrosine

CAS: 1164-16-5

N-Cbz-L-tyrosine is a covalently modified amino acid that has been shown to be an effective protease inhibitor. The compound binds to the active site of enzymes, blocking their ability to hydrolyze proteins. In addition, N-Cbz-L-tyrosine has been shown to inhibit aminopeptidases and carboxypeptidases with IC50 values of 0.5 mM and 1 mM, respectively. This protein stabilizer has been shown to have a solubility data of 0.4 g/100 mL in water and 0.3 g/100 mL in methanol. It also has a molecular weight of 184.2 g/mol and a pH optimum of 7.0 (±0.2).

Fórmula: C₁₇H₁₇NO₅

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 315.32 g/mol

Ref: 3D-FC29911

Z-L-Tyrosine extrapure, 99%

CAS: 1164-16-5

Fórmula: C₁₇H₁₇NO₅

Pureza: min. 99%

Cor e Forma: White To Off white, Crystalline powder

Peso molecular: 315.3

Ref: SR-31078

N-Cbz-L-tyrosine

Produto Controlado

CAS: 1164-16-5

Applications N-Cbz-L-tyrosine is an N-Cbz-protected form of L-Tyrosine (T899975). L-Tyrosine is an essential amino acid that exhibits in vitro antioxidant and antiradical activities. L-Tyrosine is used as a precursor to synthesize catecholamines (e.g. Norepinephrine HCl [N674500]) in human keratinocytes, and also for the synthesis of proteins and thyroid hormones.
References Gülçin, ?.: Amino Acids, 32, 431 (2007); Langen, K., et al.: Nuc. Med. Biol., 29, 625 (2002); Schallreuter, K., et al.: J. Invest. Derm., 104, 953 (1995); Zhang, W., et al.: Neuropharmacology, 47, 438 (2004)

Fórmula: C₁₇H₁₇NO₅

Cor e Forma: Neat

Peso molecular: 315.32

Ref: TR-C227855