CAS 116560-97-5

ácido 4-[[(1S)-1-[[(2S)-2-[[(2S)-2-[(1-carboxi-3-fenil-propil)amino]propanol]amino]propanol]carbamoil]-2-fenil-etil]amino]benzóico

Descrição:

A substância química conhecida como ácido 4-[[(1S)-1-[[(2S)-2-[[(2S)-2-[(1-carboxi-3-fenil-propil)amino]propanol]amino]propanol]carbamoil]-2-fenil-etil]amino]benzóico, com o número CAS 116560-97-5, é um composto orgânico complexo caracterizado por sua estrutura multifuncional, que inclui múltiplos resíduos de aminoácidos e um grupo ácido carboxílico. Este composto provavelmente exibirá propriedades típicas de peptídeos ou moléculas semelhantes a peptídeos, como solubilidade em solventes polares e potencial atividade biológica, possivelmente como um agente farmacêutico ou uma sonda bioquímica. Sua estrutura sugere a presença de centros quirais, que podem conferir propriedades estereocômicas específicas que influenciam sua interação com alvos biológicos. A presença de grupos fenila indica potencial para interações aromáticas, enquanto o grupo ácido carboxílico pode contribuir para sua acidez e capacidade de formar sais. No geral, a estrutura intrincada deste composto sugere um papel em sistemas biológicos complexos, potencialmente envolvendo interações enzimáticas ou ligação a receptores.

Fórmula: C₃₂H₃₆N₄O₇

InChI: InChI=1/C32H36N4O7/c1-20(33-26(32(42)43)18-13-22-9-5-3-6-10-22)28(37)34-21(2)29(38)36-30(39)27(19-23-11-7-4-8-12-23)35-25-16-14-24(15-17-25)31(40)41/h3-12,14-17,20-21,26-27,33,35H,13,18-19H2,1-2H3,(H,34,37)(H,40,41)(H,42,43)(H,36,38,39)/t20-,21-,26?,27-/m0/s1

SMILES: C[C@@H](C(=N[C@@H](C)C(=NC(=O)[C@H](Cc1ccccc1)Nc1ccc(cc1)C(=O)O)O)O)NC(CCc1ccccc1)C(=O)O

Sinónimos:

• N-(1-carboxy-3-phenylpropyl)-alanyl-alanyl-phenylalanine-4-aminobenzoate
• N-(1-carboxy-3-phenylpropyl)-L-alanyl-N-{(2S)-2-[(4-carboxyphenyl)amino]-3-phenylpropanoyl}-L-alaninamide

N-[(RS)-1-Carboxy-3-phenyl-propyl]-Ala-Ala-Phe-4-Abz-OH

CAS: 116560-97-5

Specific inhibitor of thimet oligopeptidase (soluble metalloendopeptidase, EC 3.4.24.15) (Ki = 0.027 ± 0.003 µM). Neprilysin (Endopeptidase-2, EC 3.4.24.11) converts Cpp-AAF-pAb into a potent inhibitor of angiotensin-converting enzyme (ACE).

Fórmula: C₃₂H₃₆N₄O₇

Pureza: 98.2%

Cor e Forma: White Powder

Peso molecular: 588.66

Ref: 01-4050213

Cpp-AAF-pAb

CAS: 116560-97-5

Cpp-AAF-pAb is a synthetic peptide that corresponds to the amino acid sequence of the C terminus of human basic fibroblast growth factor (bFGF) and has been shown to have a variety of effects on cells. It has been used in cell culture studies to measure the effect of bFGF on renal blood flow, which is an important marker for kidney disease. In addition, this peptide inhibits tumor cell growth and has antinociceptive properties in rats. The inhibition of tumor cell growth may be due to its ability to inhibit metalloendopeptidases and polyclonal antibodies.

Fórmula: C₃₂H₃₆N₄O₇

Pureza: Min. 95%

Peso molecular: 588.67 g/mol

Ref: 3D-IAP-3754-PI

N-[(RS)-1-Carboxy-3-phenyl-propyl]-Ala-Ala-Phe-4-Abz-OH trifluoroacetate salt

CAS: 116560-97-5

The N-[(RS)-1-carboxy-3-phenyl-propyl]-Ala-Ala-Phe-4-Abz-OH trifluoroacetate salt is a synthetic substrate for the study of metalloendopeptidase. This compound was used to develop a model system to study the function of human liver, and has been shown to inhibit the growth of PC12 cells. The N-[(RS)-1-Carboxy-3-phenyl-propyl]-Ala-Ala-Phe-4-Abz-OH trifluoroacetate salt is also an experimental model for congestive heart failure. This compound has been shown to increase glomerular filtration rate in experimental animals as well as basic fibroblast growth factor activity in cell culture by increasing intracellular calcium levels.

Fórmula: C₃₂H₃₆N₄O₇

Pureza: Min. 95%

Peso molecular: 588.65 g/mol

Ref: 3D-FR111118