CAS: 117091-64-2 - Etoposide phosphate

Fórmula: C₂₉H₃₁O₁₆P

InChI: InChI=1S/C29H33O16P/c1-11-38-9-20-27(42-11)23(30)24(31)29(43-20)44-25-14-7-17-16(40-10-41-17)6-13(14)21(22-15(25)8-39-28(22)32)12-4-18(36-2)26(19(5-12)37-3)45-46(33,34)35/h4-7,11,15,20-25,27,29-31H,8-10H2,1-3H3,(H2,33,34,35)/t11-,15+,20-,21-,22+,23-,24-,25-,27-,29+/m1/s1

Chave InChI: InChIKey=LIQODXNTTZAGID-OCBXBXKTSA-N

SMILES: O=C1OCC2C(OC3OC4COC(OC4C(O)C3O)C)C5=CC=6OCOC6C=C5C(C7=CC(OC)=C(OP(=O)(O)O)C(OC)=C7)C12

Sinónimos:

• (5R,5aR,8aR,9S)-5-[3,5-Dimethoxy-4-(phosphonooxy)phenyl]-9-[[4,6-O-(1R)-ethylidene-β-<span class="text-smallcaps">D</span>-glucopyranosyl]oxy]-5,8,8a,9-tetrahydrofuro[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
• (5R,5aR,8aR,9S)-9-{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methylhexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy}-5-(4-hydroxy-3,5-dimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one
• (5R,5aR,8aR,9S)-9-{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-méthylhexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy}-5-(4-hydroxy-3,5-diméthoxyphényl)-5,8,8a,9-tétrahydrofuro[3',4':6,7]naphto[2,3-d][1,3]dioxol-6(5aH)-one
• (5S,5aR,8aR,9R)-9-(4-Hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside
• 4'-Demethylepipodophyllotoxin ethylidene-.beta.-D-glucoside
• 4-[(5R,5aR)-9-({4,6-O-[(1R)-ethylidene]-beta-D-glucopyranosyl}oxy)-6-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl]-2,6-dimethoxyphenyl phosphate
• 4-[(5R,5aR,8aR,9S)-9-({4,6-O-[(1R)-ethylidene]-beta-D-glucopyranosyl}oxy)-6-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl]-2,6-dimethoxyphenyl dihydrogen phosphate
• 4′-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-beta-D-glucopyranoside)
• Bmy 40481
• Epeg
• Etopofos
• Etopophos
• Etoposide (JAN/USP)
• Etoposide (VP16)
• Etoposide 4′-phosphate
• Etoposide [USAN:BAN:INN:JAN]
• Furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5-[3,5-dimethoxy-4-(phosphonooxy)phenyl]-9-[(4,6-O-ethylidene-β-<span class="text-smallcaps">D</span>-glucopyranosyl)oxy]-5,8,8a,9-tetrahydro-, [5R-[5α,5aβ,8aα,9β(R*)]]-
• Furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5-[3,5-dimethoxy-4-(phosphonooxy)phenyl]-9-[[4,6-O-(1R)-ethylidene-β-<span class="text-smallcaps">D</span>-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-, (5R,5aR,8aR,9S)-
• Pyrano[3,2-d]-1,3-dioxin, furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one deriv.

Etoposide Phosphate

CAS: 117091-64-2

Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivatives

• Fórmula: C₂₉H₃₃O₁₆P
• Cor e Forma: White Off-White Powder
• Peso molecular: 668.15062

Etoposide 4'-Phosphate

CAS: 117091-64-2

• Peso molecular: 668.54g/mol

Etoposide Phosphate

CAS: 117091-64-2

Etoposide phosphate, a salt, hinders DNA repair by causing double-strand breaks, inhibits DNA synthesis, and …

• Fórmula: C₂₉H₃₃O₁₆P
• Cor e Forma: Solid
• Peso molecular: 668.54

Etoposide Phosphate (Etopophos)

CAS: 117091-64-2

• Fórmula: C₂₉H₃₃O₁₆P
• Cor e Forma: Neat
• Peso molecular: 668.5365

Etoposide Phosphate

CAS: 117091-64-2

• Fórmula: C₂₉H₃₃O₁₆P
• Peso molecular: 668.54

Etoposide phosphate

CAS: 117091-64-2

Topoisomerase II inhibitor; chemotherapeutic drug

• Fórmula: C₂₉H₃₃O₁₆P
• Pureza: Min. 95%
• Cor e Forma: Powder
• Peso molecular: 668.54 g/mol

Etoposide Phosphate Diammonium Salt

CAS: 117091-64-2

Applications A bioequivalent prodrug of the DNA topoisomerase II inhibitor Etoposide (E933750). Antineoplastic used in …

• Fórmula: C₂₉H₃₁O₁₆P• 2NH₄
• Cor e Forma: Neat
• Peso molecular: 668.54 + 2(34.06)