CAS 118194-13-1

Sojasaponina Ab

Descrição:

Sojasaponina Ab é uma saponina triterpenoide derivada de soja, especificamente da espécie Glycine max. É caracterizada por sua estrutura complexa, que inclui um aglicona hidrofóbica e um ou mais grupos de açúcar, contribuindo para sua natureza anfifílica. Este composto exibe várias atividades biológicas, incluindo propriedades antioxidantes, anti-inflamatórias e potenciais anticancerígenas, tornando-o de interesse tanto na pesquisa nutricional quanto farmacêutica. Sojasaponina Ab é conhecido por sua capacidade de interagir com as membranas celulares, o que pode influenciar a permeabilidade da membrana e as vias de sinalização celular. Além disso, tem sido estudado por seu papel em aumentar a biodisponibilidade de certos nutrientes e seus potenciais efeitos na saúde intestinal. O composto é tipicamente extraído de sementes de soja e pode ser analisado usando técnicas como cromatografia líquida de alta eficiência (HPLC) para avaliação de pureza e concentração. Seu perfil de segurança e eficácia em várias aplicações continua a ser objeto de pesquisa contínua, particularmente no contexto de alimentos funcionais e suplementos dietéticos.

Fórmula: C₆₇H₁₀₄O₃₃

InChI: InChI=1S/C67H104O33/c1-26(71)87-24-35-48(89-27(2)72)52(90-28(3)73)53(91-29(4)74)61(94-35)96-47-32(75)23-88-57(46(47)83)100-55-54(84)62(5,6)20-31-30-12-13-37-64(8)16-15-38(65(9,25-70)36(64)14-17-67(37,11)66(30,10)19-18-63(31,55)7)95-60-51(44(81)43(80)49(97-60)56(85)86)99-59-50(42(79)40(77)34(22-69)93-59)98-58-45(82)41(78)39(76)33(21-68)92-58/h12,31-55,57-61,68-70,75-84H,13-25H2,1-11H3,(H,85,86)/t31-,32-,33+,34+,35+,36+,37+,38-,39+,40-,41-,42-,43-,44-,45+,46+,47-,48+,49-,50+,51+,52-,53+,54-,55+,57-,58-,59-,60+,61-,63+,64-,65+,66+,67+/m0/s1

Chave InChI: InChIKey=YZNCIXVBVQRGQN-YUTHWCJWSA-N

SMILES: C[C@]12[C@@]3(C)C([C@]4([C@@](C)(CC3)[C@H](O[C@H]5[C@H](O)[C@@H](O[C@H]6[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](COC(C)=O)O6)[C@@H](O)CO5)[C@H](O)C(C)(C)C4)[H])=CC[C@@]1([C@]7(C)[C@@](CC2)([C@](CO)(C)[C@@H](O[C@H]8[C@H](O[C@H]9[C@H](O[C@@H]%10O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%10O)[C@@H](O)[C@@H](O)[C@@H](CO)O9)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O8)CC7)[H])[H]

Sinónimos:

• (3β,4β,21β,22β)-21,23-Dihydroxy-22-[[3-O-(2,3,4,6-tetra-O-acetyl-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl)-α-<smallcap>L</smallcap>-arabinopyranosyl]oxy]olean-12-en-3-yl O-β-<smallcap>D</smallcap>-glucopyranosyl-(1→2)-O-β-<smallcap>D</smallcap>-galactopyranosyl-(1→2)-β-<smallcap>D</span>-glucopyranosiduronic acid
• Soyasaponin Ab
• SoyasaponinAb
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranosiduronic acid, (3β,4β,21β,22β)-21,23-dihydroxy-22-[[3-O-(2,3,4,6-tetra-O-acetyl-β-<smallcap>D</smallcap>-glucopyranosyl)-α-<smallcap>L</smallcap>-arabinopyranosyl]oxy]olean-12-en-3-yl O-β-<smallcap>D</smallcap>-glucopyranosyl-(1→2)-O-β-<smallcap>D</span>-galactopyranosyl-(1→2)-
• Acetylsoyasaponin A1
• (3β,4β,21β,22β)-21,23-Dihydroxy-22-[[3-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-α-L-arabinopyranosyl]oxy]olean-12-en-3-yl O-β-D-glucopyranosyl-(1→2)-O-β-D-galactopyranosyl-(1→2)-β-D-glucopyranosiduronic acid
• β-D-Glucopyranosiduronic acid, (3β,4β,21β,22β)-21,23-dihydroxy-22-[[3-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-α-L-arabinopyranosyl]oxy]olean-12-en-3-yl O-β-D-glucopyranosyl-(1→2)-O-β-D-galactopyranosyl-(1→2)-
• soyosaponin Ab

Soyasaponin Ab

CAS: 118194-13-1

Fórmula: C₆₇H₁₀₄O₃₃

Peso molecular: 1437.54

Ref: 7W-GY0758

Soyasaponin Ab

CAS: 118194-13-1

Soyasaponin Ab

Pureza: ≥98%

Peso molecular: 1437.52g/mol

Ref: 54-BUP20150

Soyasaponin Ab

CAS: 118194-13-1

Soyasaponin Ab may represent a viable candidate for effective vaccine adjuvant, TLR4 receptor dependent pathway may be involved in immune stimulatory effects of soyasaponin Ab. Soyasaponin Ab has anti-inflammatory effects, it can inhibit colon shortening, myeloperoxidase activity, the expression of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS), and activation of the transcription factor nuclear factor-κB (NF-κB); soyasaponin Ab (1, 2, 5, and 10 μM) can inhibit the production of NO (IC50 = 1.6 ± 0.1 uM) and prosta. Soyasaponin Aa and Ab can markedly inhibit adipocyte differentiation and expression of various adipogenic marker genes through the downregulation of the adipogenesis-related transcription factors PPARγ and C/EBPα in 3T3-L1 adipocytes. They also can prevent scopolamine-induced memory impairment in mice without the inhibition of acetylcholinesterase, exhibit memory-enhancing effects.

Fórmula: C₆₇H₁₀₄O₃₃

Pureza: 95%~99%

Cor e Forma: Powder

Peso molecular: 1437.54

Ref: BP-BP1735

Soyasaponin Ab

CAS: 118194-13-1

Soyasaponin Ab: a potential vaccine adjuvant via TLR4 pathway.

Fórmula: C₆₇H₁₀₄O₃₃

Pureza: 98.27% - 99.79%

Cor e Forma: Solid

Peso molecular: 1437.52

Ref: TM-TN2232

Soyasaponin Ab

CAS: 118194-13-1

Soyasaponin Ab is a natural product that has immunomodulatory effects on the immune system. It inhibits the production of TNF-α, which is an inflammatory cytokine. Soyasaponin Ab also has anti-inflammatory properties and can be used to treat bowel disease. The mechanism of action is not clear, but it may be due to inhibition of fatty acid synthesis in the liver or stimulation of antioxidative enzymes. This compound is structurally similar to nonsteroidal anti-inflammatory drugs (NSAIDs). Soyasaponin Ab has been shown to inhibit LPS-induced inflammatory response and reduce metabolic disorders in vitro.

Pureza: Min. 98 Area-%

Cor e Forma: Powder

Ref: 3D-FS74366