CAS 1190379-70-4

Cyclobutanecarboxamide, N-[3-[[5-cyclopropyl-2-[(1,2,3,4-tetrahydro-2-methyl-6-isoquinolinyl)amino]-4-pyrimidinyl]amino]propyl]-

CAS: 1190379-70-4

Fórmula: C₂₅H₃₄N₆O

Pureza: 98%

Peso molecular: 434.5771

Ref: IN-DA000I41

MRT68921

CAS: 1190379-70-4

MRT68921

Pureza: ≥98%

Peso molecular: 434.58g/mol

Ref: 54-BUP05833

MRT68921

CAS: 1190379-70-4

MRT68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively.

Fórmula: C₂₅H₃₄N₆O

Pureza: 99.23%

Cor e Forma: Solid

Peso molecular: 434.58

Ref: TM-T6899

MRT 68921 dihydrochloride

CAS: 1190379-70-4

MRT 68921 dihydrochloride is a novel anthelmintic drug that inhibits the formation of autophagosomes. It has been shown to be effective against nematodes, such as parasitic nematodes and free-living nematodes, which are parasites that live in animals' intestines. The drug blocks the formation of autophagosomes by inhibiting key proteins involved in autophagy, preventing the degradation of cellular components and thus killing the parasite. MRT 68921 dihydrochloride binds to a conserved region in the cysteine protease domain of the protein Atg4B, thereby inhibiting its activity. This inhibition prevents the degradation of cellular components and leads to cell death.

Fórmula: C₂₅H₃₄N₆O

Pureza: Min. 95%

Peso molecular: 434.58 g/mol

Ref: 3D-FM172881