CAS 119141-89-8

Omeprazol

Descrição:

Omeprazol é um inibidor da bomba de prótons (IBP) usado principalmente para tratar condições como a doença do refluxo gastroesofágico (DRGE) e úlceras pépticas, reduzindo a produção de ácido estomacal. É caracterizado por sua fórmula química, que inclui um anel de benzimidazol, um grupo metóxi e uma porção de piridina, contribuindo para sua atividade farmacológica. A substância é tipicamente administrada em sua forma racêmica e é conhecida por sua alta lipofilicidade, permitindo uma absorção eficaz no trato gastrointestinal. Omeprazol é frequentemente formulado como comprimidos revestidos para proteger contra a degradação no ambiente ácido do estômago, garantindo sua liberação no pH mais neutro dos intestinos. Seu mecanismo de ação envolve a inibição irreversível da enzima H+/K+ ATPase nas células parietais gástricas, levando à diminuição da secreção de ácido gástrico. Omeprazol geralmente é bem tolerado, embora o uso a longo prazo possa estar associado a certos riscos, incluindo má absorção de nutrientes e infecções gastrointestinais.

Fórmula: C₁₇H₁₉N₃O₃S

InChI: InChI=1/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)

Chave InChI: InChIKey=SUBDBMMJDZJVOS-XMMPIXPASA-N

SMILES: S(CC1=C(C)C(OC)=C(C)C=N1)(=O)C=2NC=3C(N2)=CC=C(OC)C3

Sinónimos:

• (R)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
• (R)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole
• (R)-Esomeprazole
• 1H-Benzimidazole, 5-methoxy-2-[(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-
• 1H-Benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, (R)-
• 1H-Benzimidazole, 6-methoxy-2-[(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-
• 1H-Benzimidazole-1-acetic acid, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, (+)-
• 2-Chloromethyl-3,5-dinmethyl-4-methoxypyridine
• 5-Methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]-3H-benzoimidazole
• 6-Methoxy-2-[(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
• Losec
• Mepral
• Mopral
• Omepral
• Omerprazole
• R-(+)-Omeprazole
• Zoltum
• (S)-OMEPRAZOLE
• R-Omeparazole
• Omeprazole Impurity N
• H 168/68
• 6-methoxy-2-[(R)-(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole
• Omeprazole R-Isomer
• Esomeprazole EP Impurity F
• 2-[(4-METHOXY-3,5-DIMETHYLPYRID-2-YL)-METHYLSULFO]-5-METHOXYBENZIMIDAZOLE
• 5-Methoxy-2-[(R)-[(4-Methoxy-3,5-diMethylpyridin-2-yl)Methyl]sulfinyl]-1H-benziMidazole
• 5-METHOXY-2[(4-METHOXY-3,5-DIMETHYL-2-PYRIDYL)METHYLSULFINYL]-1H-BENZIMIDAZOLE
• EsoMeprazole iMpurity F
• Erythromycine Thiocynate
• Omeprazole Impurity 33
• ANTRA
• GASTROLOC
• omeprazole impurity B (r-omeprazole)
• Omeprazole impurity 18/(R)-Omeprazole/(R)-5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole
• Omeprazole impurity N (R)-Omeprazole
• (R)-6-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole
• GASTROGARD
• PRILOSEC
• 5-METHOXY-2-[[(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYL]SULFINYL]-1H-BENZIMIDAZOLE
• Esomeprazole Sodium Impurity 15

1H-Benzimidazole,5-methoxy-2-[(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-

CAS: 119141-89-8

Fórmula: C₁₇H₁₉N₃O₃S

Pureza: 96%

Cor e Forma: Solid

Peso molecular: 345.4161

Ref: IN-DA00HEY2

(R)-Omeprazole

CAS: 119141-89-8

Fórmula: C₁₇H₁₉N₃O₃S

Cor e Forma: Off-White Solid

Peso molecular: 345.42

Ref: 4Z-O-024

(R)-5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole

CAS: 119141-89-8

Pureza: 95.0%

Peso molecular: 345.4200134277344

Ref: 10-F448256

(R)-Omeprazole

CAS: 119141-89-8

Omeprazole is a proton pump inhibitor that inhibits gastric acid secretion by binding to the H+/K+ ATPase enzyme in the secretory canaliculi of the parietal cells. Omeprazole has been shown to have a protective effect in animal models against infection with Salmonella enterica serovar Typhimurium, and also protects against ulcers caused by Helicobacter pylori infection. Omeprazole is used as an adjunct treatment for patients with non-infectious gastroesophageal reflux disease (GERD) or active duodenal ulcers. It has also been used for the prevention of stress-related mucosal damage in critically ill patients, although it is not approved for this use. Omeprazole can be administered orally or by injection. When administered orally, omeprazole may cause gastrointestinal side effects such as nausea, abdominal pain, and diarrhea. Omeprazole can interact with other drugs such

Fórmula: C₁₇H₁₉N₃O₃S

Pureza: Min. 95%

Cor e Forma: Off-White Powder

Peso molecular: 345.42 g/mol

Ref: 3D-FO165430

(R)-Omeprazole

CAS: 119141-89-8

(R)-Omeprazole is a useful organic compound for research related to life sciences. The catalog number is T66287 and the CAS number is 119141-89-8.

Fórmula: C₁₇H₁₉N₃O₃S

Cor e Forma: Solid

Peso molecular: 345.42

Ref: TM-T66287