CAS 119478-56-7

Meropeném tri-hidratado

Descrição:

Meropeném tri-hidratado é um antibiótico de amplo espectro pertencente à classe dos carbapenêmicos, utilizado principalmente para tratar infecções bacterianas graves. É caracterizado por sua capacidade de inibir a síntese da parede celular bacteriana, tornando-o eficaz contra uma ampla gama de bactérias Gram-positivas e Gram-negativas, incluindo aquelas resistentes a outros antibióticos. A forma de trihidrato indica que o composto contém três moléculas de água por molécula de meropenem, o que pode influenciar sua solubilidade e estabilidade. O meropenem é tipicamente administrado por injeção intravenosa devido à sua baixa biodisponibilidade oral. É conhecido por suas favoráveis propriedades farmacocinéticas, incluindo uma meia-vida relativamente longa e boa penetração nos tecidos. Efeitos colaterais comuns podem incluir distúrbios gastrointestinais, dor de cabeça e reações alérgicas potenciais. Assim como outros antibióticos, o surgimento de resistência é uma preocupação, exigindo uso cuidadoso e adesão aos regimes prescritos. No geral, Meropeném tri-hidratado é uma opção crítica no tratamento de infecções graves, particularmente em ambientes hospitalares.

Fórmula: C₁₇H₂₅N₃O₅S

InChI: InChI=1/C17H25N3O5S/c1-7-12-11(8(2)21)16(23)20(12)13(17(24)25)14(7)26-9-5-10(18-6-9)15(22)19(3)4/h7-12,18,21H,5-6H2,1-4H3,(H,24,25)/t7-,8+,9-,10-,11-,12-/m0/s1

Chave InChI: InChIKey=CTUAQTBUVLKNDJ-OBZXMJSBSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@@]([C@@H](C)O)(C2=O)[H])([C@@H](C)C1S[C@H]3C[C@@H](C(N(C)C)=O)NC3)[H].O

Sinónimos:

• (4R,5S,6S)-3-[[(3S,5S)-5-(Dimethylcarbamoyl)-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid trihydrate
• (4R,5S,6S)-3-[[(3S,5S)-5-(Dimethylcarbamoyl)pyrrolidin-3-yl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• (4R,5S,6S)-3-{[(2S,5S)-5-(dimethylcarbamoyl)pyrrolidin-2-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid trihydrate
• (4S,5R,6R)-3-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(3S,5S)-5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, hydrate (1:3), (4R,5S,6S)-
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(3S,5S)-5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, trihydrate, (4R,5S,6S)-
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-, trihydrate, [4R-[3(3S*,5S*),4α,5β,6β(R*)]]-
• Meropenem (with carbonate)
• Meropenem trihydrate
• Meropenem
• 3-[[5-[(Dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3,2,0]hept-2-ene-2-carboxylic acid trihydrate
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-, trihydrate, [4R-[3(3S*,5S*),4a,5b,6b(R*)]]-(9CI)
• MEROPENEM WITH SODIUM CARBONATE
• MEROPENEM
• MEROPENEMTRIHYDRATE(3-[[5-[(DIMETHYLAMINO)CARBONYL]-3-PYRROLIDINYL]THIO]-6-(1-HYDROXYETHYL)-4-METHYL-7-OXO-1-AZABICYCLO[3,2,0]HEPT-2-ENE-2-CARBOXYLICACIDTRIHYDRATE)

Meropenem Trihydrate

CAS: 119478-56-7, 96036-03-2

Fórmula: C₁₇H₂₅N₃O₅S·3H₂O

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 437.51

Ref: 3B-M2279

Meropenem trihydrate, 98-101%

CAS: 119478-56-7

A broad spectrum antibiotic targeting a wide range of bacteria

Fórmula: C₁₇H₃₁N₃O₈S

Pureza: 98-101%

Cor e Forma: Powder or crystals or crystalline powder, White to pale yellow

Peso molecular: 437.51

Ref: 02-J66446

MEROPENEM TRIHYDRATE CRS

CAS: 119478-56-7

MEROPENEM TRIHYDRATE CRS

Fórmula: C₁₇H₂₅N₃O₅S

Cor e Forma: Added Modified

Peso molecular: 383.4625

Ref: 41-Y0001252

Meropenem

CAS: 119478-56-7

Antibiotics nesoi

Fórmula: C₁₇H₂₅N₃O₅S·3H₂O

Cor e Forma: White Light Yellow Powder

Peso molecular: 437.51

Ref: 45-1392454

(4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid trihydrate

CAS: 119478-56-7

Fórmula: C₁₇H₃₁N₃O₈S

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 437.5083

Ref: IN-DA000IV3

Meropenem trihydrate

CAS: 119478-56-7

Meropenem trihydrate (SM 7338 trihydrate) with broad-spectrum antibacterial activity,is a carbapenem antibiotic.

Fórmula: C₁₇H₃₁N₃O₈S

Pureza: 99.80%

Cor e Forma: Solid

Peso molecular: 437.51

Ref: TM-T12004

Meropenem trihydrate

CAS: 119478-56-7

Fórmula: C₁₇H₂₅N₃O₅S·3H₂O

Pureza: ≥ 98.0% (anhydrous basis)

Cor e Forma: White, off-white or faint beige crystalline powder

Peso molecular: 437.51

Ref: 7W-GP7412

Meropenem trihydrate, USP grade

CAS: 119478-56-7

Fórmula: C₁₇H₂₅N₃O₅S·3H₂O

Pureza: ≤ 0.1% (anhydrous basis)

Cor e Forma: White, off-white or faint beige crystalline powder

Peso molecular: 437.51

Ref: 7W-GP9211

Meropenem trihydrate

CAS: 119478-56-7

Meropenem trihydrate

Pureza: ≥98%

Peso molecular: 437.51g/mol

Ref: 54-BUP15105

Meropenem trihydrate

Produto Controlado

CAS: 119478-56-7

Fórmula: C₁₇H₂₅N₃O₅SH₂O

Cor e Forma: Neat

Peso molecular: 437.51

Ref: 04-C14906000

Meropenem Trihydrate

CAS: 119478-56-7

Cor e Forma: Neat

Ref: 86-MM1327.00

Meropenem RS

CAS: 119478-56-7

Cor e Forma: White To Light Yellow Solid Crystalline Powder

Ref: 2K-7000960021

Meropenem Trihydrate

Produto Controlado

CAS: 119478-56-7

Applications Meropenem Trihydrate is a carbapenem antibiotic with wide spectrum of antibacterial.
References Hickey, M.B., et al.: J. Pharma. Sci., 96, 1090 (2007); Condie, C.K., et al.: Am. J. Health. System. Pharma., 65, 454 (2008);

Fórmula: C₁₇H₂₅N₃O₅S·3H₂O

Cor e Forma: Light Yellow

Peso molecular: 437.51

Ref: TR-M225640

Meropenem Trihydrate

CAS: 119478-56-7

Fórmula: C₁₇H₂₅N₃O₅S(H₂O)

Peso molecular: 383.5 : 3(18.0)

Ref: ST-EA-CP-M30000

Meropenem trihydrate

CAS: 119478-56-7

Inhibitor of cell-wall synthesis; carbapenem class

Fórmula: C₁₇H₂₅N₃O₅S·3H₂O

Pureza: Min. 95 Area-%

Cor e Forma: Powder

Peso molecular: 437.51 g/mol

Ref: 3D-AM16380

Meropenem trihydrate, Antibiotic for Culture Media Use Only

CAS: 119478-56-7

Meropenem trihydrate has broad spectrum activity against Gram-positive and Gram-negative bacteria, as well as, some mycoplasma species. It inhibits cell wall synthesis by binding to bacterial penicillin-binding proteins (PBP), which impairs cell wall integrity, induces the formation of reactive oxygen species, and inhibits macromolecular synthesis in bacteria. It can be used to prevent bacterial growth after being exposed to meropenem through fluorescence imaging of human blood plasma. Meropenem trihydrate research studies showed a reduction of the allergen levels in patients with respiratory allergies or asthma, specifically dust mites, cockroaches, animal dander, pollen grains, etc. by inhibit allergen-induced sensitization of mast cells.

Fórmula: C₁₇H₃₁N₃O₈S

Pureza: Min. 98.0 Area-%

Peso molecular: 437.51 g/mol

Ref: 3D-M-2780

Meropenem trihydrate

CAS: 119478-56-7

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 437.51

Ref: 10-F792074