CAS: 1207456-01-6 - (8S,9R)-5-Fluoro-8-(4-fluorophenyl)-2,7,8,9-tetrahydro-9-(1-methyl-1H-1,2,4-triazol-5-yl)-3H-pyrido[4,3,2-de]phthalazine-3-one

Fórmula: C₁₉H₁₄F₂N₆O

InChI: InChI=1S/C19H14F2N6O/c1-27-18(22-8-23-27)15-16(9-2-4-10(20)5-3-9)24-13-7-11(21)6-12-14(13)17(15)25-26-19(12)28/h2-8,15-16,24H,1H3,(H,26,28)/t15-,16-/m1/s1

Chave InChI: InChIKey=HWGQMRYQVZSGDQ-HZPDHXFCSA-N

SMILES: O=C1NN=C2C=3C(=CC(F)=CC13)NC(C4=CC=C(F)C=C4)C2C5=NC=NN5C

Sinónimos:

• (8S,9R)-5-Fluoro-8-(4-fluorophenyl)-2,7,8,9-tetrahydro-9-(1-methyl-1H-1,2,4-triazol-5-yl)-3H-pyrido[4,3,2-de]phthalazin-3-one
• 3H-Pyrido[4,3,2-de]phthalazin-3-one, 5-fluoro-8-(4-fluorophenyl)-2,7,8,9-tetrahydro-9-(1-methyl-1H-1,2,4-triazol-5-yl)-, (8S,9R)-
• 5-fluoro-8-(4-fluorophenyl)-2,7,8,9-tetrahydro-9-(1-methyl-1H-1,2,4-triazol-5-yl)-3H-Pyrido[4,3,2-de]phthalazin-3-one
• Bmn-673
• Bmn673
• Talazoparib
• Talzenna

Talazoparib

CAS: 1207456-01-6

• Fórmula: C₁₉H₁₄F₂N₆O
• Pureza: ≥ 97.0%
• Cor e Forma: White to off-white powder
• Peso molecular: 380.35

Talazoparib

CAS: 1207456-01-6

Talazoparib (LT-673) is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 …

• Fórmula: C₁₉H₁₄F₂N₆O
• Pureza: 98% - 99.85%
• Cor e Forma: Solid
• Peso molecular: 380.35

(8S,9R)-5-Fluoro-8-(4-fluorophenyl)-2,7,8,9-tetrahydro-9-(1-methyl-1H-1,2,4-triazol-5-yl)-3H-pyrido[4,3,2-de]phthalazine-3-one

CAS: 1207456-01-6

Talazoparib is a small-molecule inhibitor of DNA methyltransferases (DMTs) and is currently being investigated for …

• Fórmula: C₁₉H₁₄F₂N₆O
• Pureza: Min. 95%
• Cor e Forma: Off-White To Yellow Solid
• Peso molecular: 380.35 g/mol

(8S,9R)-BMN 673

CAS: 1207456-01-6

Applications (8S,9R)-BMN 673 is a potent inhibitor of poly-ADP ribose polymerase (PARP) that has potential …

• Fórmula: C₁₉H₁₄F₂N₆O
• Cor e Forma: White to Off-White Solid
• Peso molecular: 380.35